Dact1 Gene Set

Dataset InterPro Predicted Protein Domain Annotations
Category structural or functional annotations
Type protein domain
Description dishevelled-binding antagonist of beta-catenin 1|The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 51339)
External Link https://www.ebi.ac.uk/interpro/entry/IPR024848
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1 proteins predicted to have the Dact1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Symbol Name
DACT1 dishevelled-binding antagonist of beta-catenin 1