| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.209055 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137122 |
| NDRG1 | N-myc downstream regulated 1 | 0.131929 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.111196 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.1051 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0932408 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0900995 |
| STC1 | stanniocalcin 1 | 0.0865759 |
| PRELID2 | PRELI domain containing 2 | 0.0795266 |
| LOXL2 | lysyl oxidase-like 2 | 0.0791868 |
| GOLGA4 | golgin A4 | 0.077251 |
| ATP13A3 | ATPase type 13A3 | 0.0772453 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0765518 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0738541 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0694514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0657173 |
| PDE10A | phosphodiesterase 10A | 0.0613743 |
| CALR | calreticulin | 0.0604324 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0512044 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0511427 |
| CENPF | centromere protein F, 350/400kDa | 0.0501112 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0478381 |
| RPS6 | ribosomal protein S6 | 0.0474564 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.046881 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.045998 |
| MKI67 | marker of proliferation Ki-67 | 0.0454539 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0450967 |
| ENO1 | enolase 1, (alpha) | 0.0449646 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.044782 |
| ASPH | aspartate beta-hydroxylase | 0.0443202 |
| PTMA | prothymosin, alpha | 0.0438298 |
| TMF1 | TATA element modulatory factor 1 | 0.0436891 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0436447 |
| TPR | translocated promoter region, nuclear basket protein | 0.0432742 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0431472 |
| ARRDC3 | arrestin domain containing 3 | 0.0430135 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0429436 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0417658 |
| RRBP1 | ribosome binding protein 1 | 0.040939 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0408089 |
| NAV2 | neuron navigator 2 | 0.0403967 |
| INHBA | inhibin, beta A | 0.0400977 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389375 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0389117 |
| DST | dystonin | 0.0382034 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0371356 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.037025 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0367149 |
| HSPA8 | heat shock 70kDa protein 8 | 0.035952 |
| FAM219A | family with sequence similarity 219, member A | 0.0358022 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0357374 |
| SBF2 | SET binding factor 2 | 0.0353093 |
| APP | amyloid beta (A4) precursor protein | 0.0352308 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0346692 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0342627 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0341115 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0339398 |
| FMNL2 | formin-like 2 | 0.03384 |
| UBC | ubiquitin C | 0.033745 |
| RPS2 | ribosomal protein S2 | 0.033663 |
| RBM39 | RNA binding motif protein 39 | 0.0335958 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0335602 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331615 |
| SMAD3 | SMAD family member 3 | 0.0329213 |
| ANTXR2 | anthrax toxin receptor 2 | 0.032728 |
| COG5 | component of oligomeric golgi complex 5 | 0.0325496 |
| H1-4 | H1.4 linker histone, cluster member | 0.0321721 |
| RPS3 | ribosomal protein S3 | 0.0315396 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0313981 |
| FLNB | filamin B, beta | 0.0311694 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0304853 |
| CENPE | centromere protein E, 312kDa | 0.0303952 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0302712 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0301094 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0297673 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0290079 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.028963 |
| ANLN | anillin, actin binding protein | 0.028848 |
| RPL37A | ribosomal protein L37a | 0.0288386 |
| RND3 | Rho family GTPase 3 | 0.0286263 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0286245 |
| ANO6 | anoctamin 6 | 0.0283703 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0283301 |
| MTSS1 | metastasis suppressor 1 | 0.0282161 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0281098 |
| PTK2 | protein tyrosine kinase 2 | 0.0278817 |
| GOLT1B | golgi transport 1B | 0.0276558 |
| RAI14 | retinoic acid induced 14 | 0.0274042 |
| ATF4 | activating transcription factor 4 | 0.0273958 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0273223 |
| RPS8 | ribosomal protein S8 | 0.027245 |
| YEATS2 | YEATS domain containing 2 | 0.0269281 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.0268297 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.026753 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267244 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0267184 |
| COL3A1 | collagen, type III, alpha 1 | 0.0262073 |
| NUMB | numb homolog (Drosophila) | 0.0261636 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0261613 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0260693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.189414 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128972 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.122566 |
| CADM1 | cell adhesion molecule 1 | -0.10603 |
| FN1 | fibronectin 1 | -0.078719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0759748 |
| MT2A | metallothionein 2A | -0.0758375 |
| VIM | vimentin | -0.0752236 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0742084 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0708048 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0701342 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0684271 |
| FBN1 | fibrillin 1 | -0.0627529 |
| CDH13 | cadherin 13 | -0.0627388 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0616154 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0587331 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0553851 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0532457 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0517691 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0500807 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0483665 |
| IER3 | immediate early response 3 | -0.0470472 |
| EGR1 | early growth response 1 | -0.046051 |
| POTEF | POTE ankyrin domain family, member F | -0.0459048 |
| MT1X | metallothionein 1X | -0.0448168 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0446257 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0424572 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0419441 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0415983 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0394061 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0393582 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0385502 |
| PALLD | palladin, cytoskeletal associated protein | -0.038181 |
| TMSB10 | thymosin beta 10 | -0.0378406 |
| CCND1 | cyclin D1 | -0.0373881 |
| IL6ST | interleukin 6 signal transducer | -0.0368816 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0364363 |
| HMGA1 | high mobility group AT-hook 1 | -0.0354996 |
| ACTG1 | actin gamma 1 | -0.0354422 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0353124 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.034869 |
| EGFR | epidermal growth factor receptor | -0.0345737 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0342897 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0338874 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0323771 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0323275 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0320706 |
| NREP | neuronal regeneration related protein | -0.03166 |
| FTL | ferritin, light polypeptide | -0.0308235 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0306126 |
| NABP1 | nucleic acid binding protein 1 | -0.0304772 |
| LOX | lysyl oxidase | -0.0304452 |
| TAPBP | TAP binding protein (tapasin) | -0.0300958 |
| NEK10 | NIMA-related kinase 10 | -0.0299397 |
| RYBP | RING1 and YY1 binding protein | -0.029701 |
| PDLIM5 | PDZ and LIM domain 5 | -0.029695 |
| CNTN5 | contactin 5 | -0.029565 |
| FLNA | filamin A, alpha | -0.0295622 |
| CALD1 | caldesmon 1 | -0.0291845 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0291193 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290945 |
| TRAM1 | translocation associated membrane protein 1 | -0.0289777 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028891 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0288005 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0285193 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0282119 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0281069 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0280071 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0279972 |
| DGKI | diacylglycerol kinase, iota | -0.0279771 |
| MYO10 | myosin X | -0.0278936 |
| S100A10 | S100 calcium binding protein A10 | -0.0278692 |
| QKI | QKI, KH domain containing, RNA binding | -0.0271768 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0265886 |
| AGRN | agrin | -0.0265095 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0264429 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0257261 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0256291 |
| PFN1 | profilin 1 | -0.024996 |
| AHR | aryl hydrocarbon receptor | -0.0248738 |
| FOXP1 | forkhead box P1 | -0.0248215 |
| VCL | vinculin | -0.0247756 |
| MAP1B | microtubule-associated protein 1B | -0.02451 |
| ZNF644 | zinc finger protein 644 | -0.0244818 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.024098 |
| TPM1 | tropomyosin 1 (alpha) | -0.0240054 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0239363 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0237366 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0237021 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0234594 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0229462 |
| NOTCH2 | notch 2 | -0.0225459 |
| SQSTM1 | sequestosome 1 | -0.0224009 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0223017 |
| RPL35A | ribosomal protein L35a | -0.0222842 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0221533 |
| BSG | basigin (Ok blood group) | -0.0211902 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0211862 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0210381 |
| RPL28 | ribosomal protein L28 | -0.0209671 |
