| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daidzin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.228196 |
| VEGFA | vascular endothelial growth factor A | 0.205133 |
| FNDC3B | fibronectin type III domain containing 3B | 0.129333 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.11853 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.102983 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.09887 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0922236 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0898191 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0830867 |
| AFDN | afadin, adherens junction formation factor | 0.0826803 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0741745 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0717114 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0713315 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0689232 |
| DSPP | dentin sialophosphoprotein | 0.0687085 |
| APOA2 | apolipoprotein A-II | 0.0684519 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0636335 |
| PRELID2 | PRELI domain containing 2 | 0.0593136 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0585899 |
| MT2A | metallothionein 2A | 0.0556736 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.051307 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0491066 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0490849 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0488584 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0468833 |
| TNS1 | tensin 1 | 0.0465478 |
| TMSB10 | thymosin beta 10 | 0.0462063 |
| KIAA1217 | KIAA1217 | 0.0459381 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0456388 |
| C3 | complement component 3 | 0.045402 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.044542 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0439541 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0438478 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.0413211 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.040348 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0401445 |
| INSIG2 | insulin induced gene 2 | 0.0397248 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387129 |
| TMEM45B | transmembrane protein 45B | 0.0383729 |
| FRMD5 | FERM domain containing 5 | 0.03733 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0372558 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0369686 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0368533 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0350822 |
| LDHA | lactate dehydrogenase A | 0.0348312 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0338606 |
| OPTN | optineurin | 0.0337804 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.033649 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0336126 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0335105 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.032776 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0318698 |
| PEG3 | paternally expressed 3 | 0.0318163 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0317729 |
| ZNF292 | zinc finger protein 292 | 0.0316421 |
| KIZ | kizuna centrosomal protein | 0.0311475 |
| KIF1B | kinesin family member 1B | 0.0310704 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310378 |
| FNIP1 | folliculin interacting protein 1 | 0.0306677 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0306651 |
| MALT1 | MALT1 paracaspase | 0.0305148 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.030265 |
| CDK19 | cyclin-dependent kinase 19 | 0.0294947 |
| SBF2 | SET binding factor 2 | 0.0290398 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0290326 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.028926 |
| NDRG1 | N-myc downstream regulated 1 | 0.0288236 |
| MKI67 | marker of proliferation Ki-67 | 0.0286863 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0286583 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0283459 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0273405 |
| CRLS1 | cardiolipin synthase 1 | 0.0272989 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.027273 |
| ARFGEF3 | ARFGEF family member 3 | 0.0271796 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0271696 |
| HELZ | helicase with zinc finger | 0.027077 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0270558 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0270064 |
| HLA-A | major histocompatibility complex, class I, A | 0.0268898 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0268257 |
| ENO1 | enolase 1, (alpha) | 0.0268109 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0267392 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0266786 |
| TPD52 | tumor protein D52 | 0.0265227 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.026508 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0259871 |
| PDE8A | phosphodiesterase 8A | 0.0258377 |
| VIM | vimentin | 0.025773 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0256119 |
| VCAN | versican | 0.0253526 |
| RPL37A | ribosomal protein L37a | 0.0250978 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0250964 |
| PTK2 | protein tyrosine kinase 2 | 0.0250299 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0249005 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0248565 |
| MATR3 | matrin 3 | 0.0245295 |
| YAP1 | Yes-associated protein 1 | 0.0245127 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0244574 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0243897 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0242719 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.179738 |
| IGF2 | insulin-like growth factor 2 | -0.123674 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.109452 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.102991 |
| GPC6 | glypican 6 | -0.0784067 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0733928 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0703295 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0671755 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0660205 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0655481 |
| RPS24 | ribosomal protein S24 | -0.0624635 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0620514 |
| FOXP1 | forkhead box P1 | -0.0619065 |
| INTS6 | integrator complex subunit 6 | -0.0601238 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0577654 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0563367 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0542477 |
| CANX | calnexin | -0.0526341 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0522803 |
| FAM107B | family with sequence similarity 107, member B | -0.0519839 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.051702 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0513793 |
| GPC3 | glypican 3 | -0.0508535 |
| FN1 | fibronectin 1 | -0.050216 |
| EHBP1 | EH domain binding protein 1 | -0.0491582 |
| CP | ceruloplasmin (ferroxidase) | -0.0488647 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0445438 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0436649 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0433252 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0430388 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0426078 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0419455 |
| SMAD3 | SMAD family member 3 | -0.0412321 |
| SELENOP | selenoprotein P | -0.0411173 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0411071 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0406702 |
| RPS27A | ribosomal protein S27a | -0.0403844 |
| LOC112694756 | uncharaterized LOC112694756 | -0.040337 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0395843 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0391066 |
| SVIL | supervillin | -0.0387813 |
| PTCHD4 | patched domain containing 4 | -0.0387128 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0376363 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.037248 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0366469 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0363729 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0358437 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0354367 |
| UBC | ubiquitin C | -0.0350149 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0349428 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0346082 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.03346 |
| GOLGB1 | golgin B1 | -0.033445 |
| MCU | mitochondrial calcium uniporter | -0.0333171 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0321533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0317483 |
| CLTC | clathrin, heavy chain (Hc) | -0.031735 |
| RPS8 | ribosomal protein S8 | -0.0317242 |
| USP34 | ubiquitin specific peptidase 34 | -0.0316877 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0316263 |
| HDLBP | high density lipoprotein binding protein | -0.0316068 |
| ACYP2 | acylphosphatase 2, muscle type | -0.0312982 |
| GK | glycerol kinase | -0.0310562 |
| PCBP2 | poly(rC) binding protein 2 | -0.0307751 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0307107 |
| LMO7 | LIM domain 7 | -0.0305732 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0303118 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0301671 |
| ASPH | aspartate beta-hydroxylase | -0.0300499 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0296714 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0295962 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0295334 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.029446 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0291837 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0291379 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290452 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0286051 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0285923 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0283386 |
| RPS13 | ribosomal protein S13 | -0.0282652 |
| RBM39 | RNA binding motif protein 39 | -0.0282566 |
| CDK13 | cyclin-dependent kinase 13 | -0.027945 |
| RPS2 | ribosomal protein S2 | -0.0277557 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276266 |
| NABP1 | nucleic acid binding protein 1 | -0.0275977 |
| TXNRD1 | thioredoxin reductase 1 | -0.0275026 |
| GPHN | gephyrin | -0.0274251 |
| EXOC6B | exocyst complex component 6B | -0.0273973 |
| PHF14 | PHD finger protein 14 | -0.0272994 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0269547 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267671 |
| BCL2L1 | BCL2-like 1 | -0.0266211 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0264692 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0264618 |
| FTL | ferritin, light polypeptide | -0.0264589 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0263996 |
| ITGA1 | integrin, alpha 1 | -0.0261465 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0261435 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0260911 |
| RPL5 | ribosomal protein L5 | -0.0259556 |
