| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.129761 |
| MT2A | metallothionein 2A | 0.0889651 |
| ARRDC3 | arrestin domain containing 3 | 0.0678374 |
| PDE8A | phosphodiesterase 8A | 0.0670483 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0658231 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0656702 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0616978 |
| MKI67 | marker of proliferation Ki-67 | 0.0586257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0578268 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0543707 |
| LAMC2 | laminin, gamma 2 | 0.0523099 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0498194 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.04879 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0459927 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0454246 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0453482 |
| NGLY1 | N-glycanase 1 | 0.0446641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0444255 |
| LMO7 | LIM domain 7 | 0.0435853 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0432879 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0424136 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0419853 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0407704 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0396088 |
| CD163L1 | CD163 molecule-like 1 | 0.0379259 |
| GOLGA4 | golgin A4 | 0.0377675 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0375485 |
| SLMAP | sarcolemma associated protein | 0.0374142 |
| MT1X | metallothionein 1X | 0.0373925 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0366039 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365434 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0361951 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0359148 |
| RAB27B | RAB27B, member RAS oncogene family | 0.034777 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0347365 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0339749 |
| TPD52 | tumor protein D52 | 0.0333654 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0326929 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.03237 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0318211 |
| RPS6 | ribosomal protein S6 | 0.031178 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0310951 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0310854 |
| SETD5 | SET domain containing 5 | 0.0309315 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0305021 |
| MED13L | mediator complex subunit 13-like | 0.0290189 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0285517 |
| HELZ | helicase with zinc finger | 0.0284515 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.027772 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270714 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0265233 |
| STC1 | stanniocalcin 1 | 0.0263947 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0263206 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0260802 |
| OGA | O-GlcNAcase | 0.0257849 |
| RPS8 | ribosomal protein S8 | 0.0257753 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0257621 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0256338 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0251761 |
| USP47 | ubiquitin specific peptidase 47 | 0.0250126 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0249561 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248219 |
| ATP13A3 | ATPase type 13A3 | 0.0245844 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.02444 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0243338 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0242326 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0236781 |
| RPL12 | ribosomal protein L12 | 0.0236135 |
| SERF2 | small EDRK-rich factor 2 | 0.0233747 |
| MSN | moesin | 0.0232795 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0230738 |
| TPM3 | tropomyosin 3 | 0.0227978 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0223752 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.022366 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0220794 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0220608 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0219367 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0219058 |
| RPS2 | ribosomal protein S2 | 0.0217956 |
| S100A9 | S100 calcium binding protein A9 | 0.0217203 |
| RNF145 | ring finger protein 145 | 0.0215022 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0213815 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0213546 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0213403 |
| PHF21A | PHD finger protein 21A | 0.0212935 |
| PTK2 | protein tyrosine kinase 2 | 0.0212284 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0211567 |
| SEC61G | Sec61 gamma subunit | 0.0210858 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0209408 |
| ANO6 | anoctamin 6 | 0.0208415 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0207847 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0205837 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.020582 |
| KRT18 | keratin 18, type I | 0.0205142 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0204652 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0203504 |
| S100A6 | S100 calcium binding protein A6 | 0.0203136 |
| TMEM167A | transmembrane protein 167A | 0.0202822 |
| NPTN | neuroplastin | 0.0201685 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0201607 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.252504 |
| EGFR | epidermal growth factor receptor | -0.21367 |
| TXNRD1 | thioredoxin reductase 1 | -0.168361 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153906 |
| LOC112694756 | uncharaterized LOC112694756 | -0.144108 |
| PKM | pyruvate kinase, muscle | -0.0927441 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0841002 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0812339 |
| UBC | ubiquitin C | -0.0796406 |
| INTS6 | integrator complex subunit 6 | -0.0790072 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0783217 |
| LDHA | lactate dehydrogenase A | -0.0762863 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0710209 |
| EGR1 | early growth response 1 | -0.0702703 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0677376 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0645371 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0640127 |
| FTL | ferritin, light polypeptide | -0.0637802 |
| HDLBP | high density lipoprotein binding protein | -0.0614705 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0609689 |
| RPS24 | ribosomal protein S24 | -0.0555279 |
| RPLP1 | ribosomal protein, large, P1 | -0.0552187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0548997 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0544096 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0538077 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0533268 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.051712 |
| TMSB10 | thymosin beta 10 | -0.0514344 |
| ACTG1 | actin gamma 1 | -0.0503286 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.049328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.045773 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0454366 |
| ARF1 | ADP-ribosylation factor 1 | -0.0454127 |
| USP34 | ubiquitin specific peptidase 34 | -0.0421457 |
| RPL31 | ribosomal protein L31 | -0.041753 |
| NABP1 | nucleic acid binding protein 1 | -0.0412531 |
| CANX | calnexin | -0.0401741 |
| RPL4 | ribosomal protein L4 | -0.0399552 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0393504 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0376526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0368862 |
| RPS25 | ribosomal protein S25 | -0.0360152 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0359792 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0348383 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0348296 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0343182 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0342707 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0340907 |
| TES | testin LIM domain protein | -0.0338929 |
| ABLIM1 | actin binding LIM protein 1 | -0.033466 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0330085 |
| ANXA2 | annexin A2 | -0.0329477 |
| HOMER1 | homer scaffolding protein 1 | -0.0327134 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0321362 |
| CST3 | cystatin C | -0.0316428 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.031635 |
| MYOF | myoferlin | -0.0314364 |
| AGR2 | anterior gradient 2 | -0.0304952 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0304511 |
| MORF4L2 | mortality factor 4 like 2 | -0.0295912 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0291299 |
| SRPRA | SRP receptor subunit alpha | -0.0282262 |
| GM2A | GM2 ganglioside activator | -0.0280573 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.027817 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0278062 |
| SP100 | SP100 nuclear antigen | -0.0277643 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0275855 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0267424 |
| MYO1E | myosin IE | -0.0266576 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.026447 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263319 |
| TKT | transketolase | -0.0262996 |
| PCBP2 | poly(rC) binding protein 2 | -0.0262721 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0259381 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0257072 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0256756 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.025514 |
| RNF213 | ring finger protein 213 | -0.0249063 |
| PGK1 | phosphoglycerate kinase 1 | -0.0247271 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0238846 |
| MCL1 | myeloid cell leukemia 1 | -0.0237321 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0236749 |
| HYOU1 | hypoxia up-regulated 1 | -0.0236582 |
| CDCP1 | CUB domain containing protein 1 | -0.0235444 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0234608 |
| ENO1 | enolase 1, (alpha) | -0.0231157 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0221512 |
| ZNF207 | zinc finger protein 207 | -0.0220542 |
| TMEM165 | transmembrane protein 165 | -0.0219651 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0219446 |
| GRAMD1B | GRAM domain containing 1B | -0.0217316 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0217066 |
| CCND1 | cyclin D1 | -0.0216998 |
| CSNK1E | casein kinase 1, epsilon | -0.0216392 |
| HMGA1 | high mobility group AT-hook 1 | -0.0214409 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.021388 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.021351 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0213143 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0213011 |
| SCFD1 | sec1 family domain containing 1 | -0.0212295 |
