| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daidzin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.186743 |
| SMAD3 | SMAD family member 3 | 0.0951556 |
| VEGFA | vascular endothelial growth factor A | 0.0929771 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0883485 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0718719 |
| GOLGA4 | golgin A4 | 0.0687565 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0686215 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0681645 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0657573 |
| NDRG1 | N-myc downstream regulated 1 | 0.0640326 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0620946 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0620477 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0604438 |
| OPTN | optineurin | 0.0573049 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0565238 |
| FAM13A | family with sequence similarity 13, member A | 0.0559408 |
| NAV2 | neuron navigator 2 | 0.0555002 |
| RUNX1 | runt-related transcription factor 1 | 0.0484003 |
| ARRDC3 | arrestin domain containing 3 | 0.0478852 |
| FLNB | filamin B, beta | 0.0472945 |
| OSMR | oncostatin M receptor | 0.0472745 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0464524 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0442425 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0441437 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0436782 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0409454 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0401652 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0397752 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0394723 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0385684 |
| DOCK5 | dedicator of cytokinesis 5 | 0.038147 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.037708 |
| SIK3 | SIK family kinase 3 | 0.0357672 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0356772 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0355377 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0346189 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.03439 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0340919 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340128 |
| FAM107B | family with sequence similarity 107, member B | 0.0328998 |
| CA12 | carbonic anhydrase XII | 0.0327511 |
| RNF24 | ring finger protein 24 | 0.0325062 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0322731 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.032043 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0319763 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0317021 |
| RPS2 | ribosomal protein S2 | 0.0316961 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0315521 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0313644 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0312018 |
| FOXO3 | forkhead box O3 | 0.0311651 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0306791 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303489 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0302114 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0300148 |
| ANO6 | anoctamin 6 | 0.029679 |
| SFTPA2 | surfactant protein A2 | 0.0295633 |
| RUNX2 | runt-related transcription factor 2 | 0.0295461 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292346 |
| ADM | adrenomedullin | 0.0289894 |
| LOXL2 | lysyl oxidase-like 2 | 0.0288772 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0283694 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0283545 |
| TGM2 | transglutaminase 2 | 0.0283451 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.028088 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0280319 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0269208 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0266188 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0264836 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.026335 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.026276 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0262019 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0260935 |
| SLTM | SAFB-like, transcription modulator | 0.0255831 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0253822 |
| YEATS2 | YEATS domain containing 2 | 0.0252498 |
| NGLY1 | N-glycanase 1 | 0.0250189 |
| LRRC49 | leucine rich repeat containing 49 | 0.0249224 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0247764 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0246142 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245628 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0245262 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0241785 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0238877 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0236241 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0234688 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0233023 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0232108 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0230771 |
| IL1R1 | interleukin 1 receptor, type I | 0.0228973 |
| ADD3 | adducin 3 (gamma) | 0.0228832 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0227322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0225064 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0224082 |
| CENPF | centromere protein F, 350/400kDa | 0.0223404 |
| EEA1 | early endosome antigen 1 | 0.0223011 |
| ZNF292 | zinc finger protein 292 | 0.022295 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0222901 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0221517 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0221437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.227897 |
| FTL | ferritin, light polypeptide | -0.138212 |
| CDH13 | cadherin 13 | -0.106054 |
| TMSB10 | thymosin beta 10 | -0.105736 |
| VIM | vimentin | -0.104959 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.101139 |
| NRG1 | neuregulin 1 | -0.0857884 |
| PCBP2 | poly(rC) binding protein 2 | -0.0818169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0817069 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.07564 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.069976 |
| RPS24 | ribosomal protein S24 | -0.0667733 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0667506 |
| PTMA | prothymosin, alpha | -0.0618613 |
| RPLP1 | ribosomal protein, large, P1 | -0.0587143 |
| MTSS1 | metastasis suppressor 1 | -0.0548766 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.052229 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.052173 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0520371 |
| GLCCI1 | glucocorticoid induced 1 | -0.0515191 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0514713 |
| RPL35A | ribosomal protein L35a | -0.0511926 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0507269 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0498462 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0489103 |
| RPLP0 | ribosomal protein, large, P0 | -0.0478447 |
| HMGA1 | high mobility group AT-hook 1 | -0.0474134 |
| FN1 | fibronectin 1 | -0.0459702 |
| HMGA2 | high mobility group AT-hook 2 | -0.0452021 |
| IER3 | immediate early response 3 | -0.0447478 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0447091 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0439131 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0433339 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.043066 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0427619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0420303 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0418673 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0410447 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0402415 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0389982 |
| PTK2 | protein tyrosine kinase 2 | -0.0387785 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0374564 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0374093 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0373517 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0369895 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0356728 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0354737 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0352803 |
| MECOM | MDS1 and EVI1 complex locus | -0.0348682 |
| CANX | calnexin | -0.0346053 |
| IFI44L | interferon-induced protein 44-like | -0.0344486 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0339739 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0335687 |
| TXNRD1 | thioredoxin reductase 1 | -0.0335069 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332846 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0332607 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.033128 |
| POTEF | POTE ankyrin domain family, member F | -0.0330984 |
| TMEM165 | transmembrane protein 165 | -0.0328959 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0326203 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0320424 |
| AADAC | arylacetamide deacetylase | -0.0317978 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0317843 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0314726 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0311627 |
| CLIC4 | chloride intracellular channel 4 | -0.0310446 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.03091 |
| RPS11 | ribosomal protein S11 | -0.0303753 |
| PARD3 | par-3 family cell polarity regulator | -0.0303122 |
| EGR1 | early growth response 1 | -0.0301108 |
| RPL4 | ribosomal protein L4 | -0.0298495 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0297255 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0293587 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0293102 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0292674 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0291707 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0289189 |
| RPS25 | ribosomal protein S25 | -0.0286895 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0286617 |
| PGK1 | phosphoglycerate kinase 1 | -0.0286431 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0284291 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0283616 |
| NAV3 | neuron navigator 3 | -0.0281505 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0280693 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0280478 |
| INTS6 | integrator complex subunit 6 | -0.0279341 |
| FBXO11 | F-box protein 11 | -0.027618 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0276112 |
| WLS | wntless Wnt ligand secretion mediator | -0.0275231 |
| TJP1 | tight junction protein 1 | -0.0274618 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0273719 |
| SP100 | SP100 nuclear antigen | -0.0273166 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0272568 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0271624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0271025 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0270183 |
| ANXA10 | annexin A10 | -0.0270078 |
| AHNAK | AHNAK nucleoprotein | -0.0268738 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0268114 |
| S100A6 | S100 calcium binding protein A6 | -0.026686 |
