| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.112704 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.10109 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0763014 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0633965 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.062715 |
| FMNL2 | formin-like 2 | 0.0588594 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0558253 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0555178 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0553454 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0539434 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0524401 |
| TPD52 | tumor protein D52 | 0.0515434 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0497006 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0487341 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0484831 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0472732 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0469127 |
| FLNB | filamin B, beta | 0.0464845 |
| DST | dystonin | 0.0437873 |
| TPM3 | tropomyosin 3 | 0.0429767 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0416788 |
| RPL37A | ribosomal protein L37a | 0.0413061 |
| MKI67 | marker of proliferation Ki-67 | 0.0395657 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0371415 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0369722 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0346821 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339183 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0327208 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0326779 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0322098 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0315986 |
| VEGFA | vascular endothelial growth factor A | 0.0313623 |
| YTHDC1 | YTH domain containing 1 | 0.031046 |
| SPAG5 | sperm associated antigen 5 | 0.0310187 |
| SFTPA2 | surfactant protein A2 | 0.0307682 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.03066 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0305876 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0303575 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0301584 |
| RPL3 | ribosomal protein L3 | 0.0295403 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0294589 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0293433 |
| CALR | calreticulin | 0.0292329 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0292062 |
| SNX14 | sorting nexin 14 | 0.0290671 |
| RPS2 | ribosomal protein S2 | 0.0288576 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0282996 |
| MSN | moesin | 0.0282279 |
| GOLGA4 | golgin A4 | 0.0281829 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0281389 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.027971 |
| CASC3 | cancer susceptibility candidate 3 | 0.0279074 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0275397 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0275084 |
| RPS18 | ribosomal protein S18 | 0.0273192 |
| LAMB1 | laminin, beta 1 | 0.0266349 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0266197 |
| SMAD3 | SMAD family member 3 | 0.0266109 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0262976 |
| PNN | pinin, desmosome associated protein | 0.0261687 |
| SBF2 | SET binding factor 2 | 0.0261637 |
| WAC | WW domain containing adaptor with coiled-coil | 0.026106 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0260258 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0257635 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.025706 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0240011 |
| DNMBP | dynamin binding protein | 0.0238463 |
| UBC | ubiquitin C | 0.0237634 |
| FDPS | farnesyl diphosphate synthase | 0.0237269 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0235545 |
| PTMA | prothymosin, alpha | 0.0234087 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0234028 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0231362 |
| CCNY | cyclin Y | 0.0228349 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0227815 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.022545 |
| KIAA0319 | KIAA0319 | 0.0224706 |
| CTTN | cortactin | 0.0221954 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0219999 |
| CFDP1 | craniofacial development protein 1 | 0.0219768 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0219379 |
| RCOR1 | REST corepressor 1 | 0.0218397 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0217948 |
| APP | amyloid beta (A4) precursor protein | 0.0217217 |
| RPS3 | ribosomal protein S3 | 0.021363 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0213267 |
| RPS6 | ribosomal protein S6 | 0.0210124 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0208943 |
| MEAK7 | MTOR associated protein, eak-7 homolog | 0.0208109 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0207902 |
| ANXA1 | annexin A1 | 0.0206461 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0204476 |
| CMIP | c-Maf inducing protein | 0.0203446 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0202886 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0202594 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0201622 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0199083 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0197915 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0197466 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0196098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.201672 |
| FTL | ferritin, light polypeptide | -0.198365 |
| VIM | vimentin | -0.182354 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.140118 |
| TXNRD1 | thioredoxin reductase 1 | -0.132911 |
| PM20D1 | peptidase M20 domain containing 1 | -0.126938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.098547 |
| RPL4 | ribosomal protein L4 | -0.0849273 |
| RPLP1 | ribosomal protein, large, P1 | -0.0792704 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0766509 |
| POTEF | POTE ankyrin domain family, member F | -0.0717452 |
| EGR1 | early growth response 1 | -0.0676048 |
| HDAC9 | histone deacetylase 9 | -0.065937 |
| IER3 | immediate early response 3 | -0.0655963 |
| OSMR | oncostatin M receptor | -0.0654177 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0640942 |
| RPL19 | ribosomal protein L19 | -0.0639499 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.062253 |
| RPS24 | ribosomal protein S24 | -0.0607564 |
| RPL35A | ribosomal protein L35a | -0.0600995 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0599979 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0585573 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0578746 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0562296 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.055752 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0555054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0549251 |
| MORF4L2 | mortality factor 4 like 2 | -0.0539184 |
| S100A6 | S100 calcium binding protein A6 | -0.0524741 |
| RHOA | ras homolog family member A | -0.0500455 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0490317 |
| ACTG1 | actin gamma 1 | -0.0485117 |
| RPS20 | ribosomal protein S20 | -0.048157 |
| MT2A | metallothionein 2A | -0.0462294 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0453539 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.044487 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0431246 |
| RBM39 | RNA binding motif protein 39 | -0.0429884 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0427964 |
| PCBP2 | poly(rC) binding protein 2 | -0.0427763 |
| SDC4 | syndecan 4 | -0.0415527 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0415105 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0396888 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0391691 |
| RPLP0 | ribosomal protein, large, P0 | -0.0388082 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0387954 |
| ZNF207 | zinc finger protein 207 | -0.0386599 |
| CAVIN1 | caveolae associated protein 1 | -0.0384973 |
| LDHA | lactate dehydrogenase A | -0.0383443 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0380124 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0379584 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0376092 |
| MORF4L1 | mortality factor 4 like 1 | -0.0374526 |
| ANXA2 | annexin A2 | -0.0374478 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0374022 |
| BICC1 | BicC family RNA binding protein 1 | -0.0373788 |
| DENND4A | DENN/MADD domain containing 4A | -0.0364036 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0362904 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0358058 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.035773 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0356565 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0352763 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0351484 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0346145 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0338152 |
| USP3 | ubiquitin specific peptidase 3 | -0.0338096 |
| GNAS | GNAS complex locus | -0.0335421 |
| RPS5 | ribosomal protein S5 | -0.0331465 |
| PKM | pyruvate kinase, muscle | -0.0331053 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0328372 |
| RPL23 | ribosomal protein L23 | -0.0324809 |
| TPM4 | tropomyosin 4 | -0.032124 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0319791 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0316895 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0313658 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0313616 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0310774 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0303094 |
| ERBIN | erbb2 interacting protein | -0.0296263 |
| RPS16 | ribosomal protein S16 | -0.0290588 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0289194 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0285282 |
| NABP1 | nucleic acid binding protein 1 | -0.0284394 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0281576 |
| WWOX | WW domain containing oxidoreductase | -0.0281255 |
| OLA1 | Obg-like ATPase 1 | -0.028123 |
| NPR2 | natriuretic peptide receptor 2 | -0.027851 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0278395 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0276675 |
| NOP58 | NOP58 ribonucleoprotein | -0.0271625 |
| ZNF804A | zinc finger protein 804A | -0.0271106 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0270361 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0269282 |
| YBX3 | Y box binding protein 3 | -0.0267825 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0267723 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0265997 |
| PERP | PERP, TP53 apoptosis effector | -0.0265407 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0263777 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0262817 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0262615 |
