| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.116336 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.107936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0912997 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0877553 |
| GOLGA4 | golgin A4 | 0.0876933 |
| INHBA | inhibin, beta A | 0.078105 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.076894 |
| FAM13A | family with sequence similarity 13, member A | 0.0764928 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0759244 |
| OGA | O-GlcNAcase | 0.0722232 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0696709 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0694317 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0676746 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0673516 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0672879 |
| STC1 | stanniocalcin 1 | 0.0671559 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0657026 |
| CCNY | cyclin Y | 0.0642322 |
| VEGFA | vascular endothelial growth factor A | 0.0637265 |
| FNBP1L | formin binding protein 1-like | 0.0601357 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0585044 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0580674 |
| DST | dystonin | 0.0569674 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0563491 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0553721 |
| SBF2 | SET binding factor 2 | 0.0552638 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0542575 |
| RORA | RAR-related orphan receptor A | 0.0539495 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0523213 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0517309 |
| YTHDC1 | YTH domain containing 1 | 0.0516009 |
| NGLY1 | N-glycanase 1 | 0.0492105 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0490395 |
| ATP13A3 | ATPase type 13A3 | 0.0489465 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0482417 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0470646 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0463189 |
| RPS3 | ribosomal protein S3 | 0.0456317 |
| ZNF654 | zinc finger protein 654 | 0.0453197 |
| GPHN | gephyrin | 0.045201 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0449753 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0449537 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0436624 |
| HLA-B | major histocompatibility complex, class I, B | 0.0430737 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0426141 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0425493 |
| DTNA | dystrobrevin, alpha | 0.0425257 |
| MYO1B | myosin IB | 0.042478 |
| RLF | rearranged L-myc fusion | 0.0422477 |
| NDRG1 | N-myc downstream regulated 1 | 0.042124 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0418681 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0417657 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0416929 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0416285 |
| VGLL4 | vestigial-like family member 4 | 0.0416084 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0414235 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0409893 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0409129 |
| USP3 | ubiquitin specific peptidase 3 | 0.0408094 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0405017 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0403823 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0402516 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0401876 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.039954 |
| SMAD3 | SMAD family member 3 | 0.0399503 |
| SETD5 | SET domain containing 5 | 0.0391279 |
| MEMO1 | mediator of cell motility 1 | 0.038781 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0383607 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0383534 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0380352 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0379651 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.037577 |
| XPO1 | exportin 1 | 0.0375224 |
| NAV1 | neuron navigator 1 | 0.0373723 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.037284 |
| STAG2 | stromal antigen 2 | 0.0369023 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0366757 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0365837 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0365003 |
| CERT1 | ceramide transporter 1 | 0.0362017 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0361599 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0361189 |
| PRKCA | protein kinase C, alpha | 0.0350544 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0350179 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.034554 |
| TTBK2 | tau tubulin kinase 2 | 0.0345179 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0342168 |
| NCKAP1 | NCK-associated protein 1 | 0.0341668 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0340736 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0338942 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0338709 |
| NPAS2 | neuronal PAS domain protein 2 | 0.033658 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0335505 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0335052 |
| PTEN | phosphatase and tensin homolog | 0.0331126 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0330919 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0330315 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0327915 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0327505 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0326202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13014 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128787 |
| FTL | ferritin, light polypeptide | -0.117976 |
| LMO7 | LIM domain 7 | -0.117614 |
| MYO1E | myosin IE | -0.109574 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0969202 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0933576 |
| S100A9 | S100 calcium binding protein A9 | -0.0819918 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0804327 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0796213 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0782095 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0730316 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0662288 |
| MUC16 | mucin 16, cell surface associated | -0.0648892 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0646281 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.064416 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0644043 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0636547 |
| KYNU | kynureninase | -0.0616349 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0597043 |
| KRT17 | keratin 17, type I | -0.0594571 |
| SQSTM1 | sequestosome 1 | -0.0586184 |
| VIM | vimentin | -0.0573518 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0571126 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0566278 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0564466 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0554442 |
| POTEF | POTE ankyrin domain family, member F | -0.0549913 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0538811 |
| ABHD17C | abhydrolase domain containing 17C | -0.0535674 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0531784 |
| ATOSA | atos homolog A | -0.0516912 |
| ANXA1 | annexin A1 | -0.0507434 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0500901 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0494387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0493415 |
| KPNB1 | karyopherin (importin) beta 1 | -0.048032 |
| ANXA2 | annexin A2 | -0.0477688 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0474516 |
| EGR1 | early growth response 1 | -0.0470383 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.045774 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.045625 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0447835 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0445774 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0444095 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0437962 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0437824 |
| STK17A | serine/threonine kinase 17a | -0.0436389 |
| ACTG1 | actin gamma 1 | -0.0434081 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0431478 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0429371 |
| UBC | ubiquitin C | -0.0427819 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0424811 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0418059 |
| SP100 | SP100 nuclear antigen | -0.041342 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0407276 |
| EZR | ezrin | -0.0404014 |
| PLAUR | plasminogen activator, urokinase receptor | -0.039178 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0389755 |
| KIF13B | kinesin family member 13B | -0.0388475 |
| LAMC2 | laminin, gamma 2 | -0.0387457 |
| CYTH1 | cytohesin 1 | -0.0386525 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0385623 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0383453 |
| S100A10 | S100 calcium binding protein A10 | -0.0380587 |
| RPS19 | ribosomal protein S19 | -0.0379942 |
| RIGI | RNA sensor RIG-I | -0.0376983 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0371582 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0368521 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0367751 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0367238 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0366487 |
| ANTXR2 | anthrax toxin receptor 2 | -0.035827 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0357987 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.03578 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0357781 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.035697 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0356853 |
| MED13 | mediator complex subunit 13 | -0.0356512 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0355111 |
| CLINT1 | clathrin interactor 1 | -0.0354833 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0353406 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0351203 |
| MFSD14A | major facilitator superfamily domain containing 14A | -0.0348101 |
| SLMAP | sarcolemma associated protein | -0.0346746 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0346392 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0343569 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0342933 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0341281 |
| RPL23 | ribosomal protein L23 | -0.0338364 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0338226 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337554 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0337531 |
| ZNF609 | zinc finger protein 609 | -0.0336804 |
| CCDC6 | coiled-coil domain containing 6 | -0.0336604 |
| FHIT | fragile histidine triad | -0.0333919 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0333107 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0330542 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0329362 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0324909 |
