| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.267575 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.139953 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.131556 |
| FNDC3B | fibronectin type III domain containing 3B | 0.118483 |
| VEGFA | vascular endothelial growth factor A | 0.117947 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104719 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0912318 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0803527 |
| ARRDC3 | arrestin domain containing 3 | 0.0800428 |
| TPM3 | tropomyosin 3 | 0.0794012 |
| GOLGA4 | golgin A4 | 0.0783293 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0740079 |
| HSPA8 | heat shock 70kDa protein 8 | 0.073627 |
| LAMC2 | laminin, gamma 2 | 0.0730046 |
| FAM13A | family with sequence similarity 13, member A | 0.0723107 |
| RPS6 | ribosomal protein S6 | 0.0680762 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0677516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.067193 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0665672 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0653043 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0648681 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0618356 |
| RPS3 | ribosomal protein S3 | 0.0615999 |
| ASPH | aspartate beta-hydroxylase | 0.0614286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0613218 |
| RPS8 | ribosomal protein S8 | 0.0612168 |
| NAV2 | neuron navigator 2 | 0.0572571 |
| SQSTM1 | sequestosome 1 | 0.0570816 |
| RPS12 | ribosomal protein S12 | 0.0569812 |
| G0S2 | G0/G1 switch 2 | 0.0560278 |
| CALR | calreticulin | 0.0533769 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.053259 |
| LAMB3 | laminin, beta 3 | 0.0506692 |
| DSPP | dentin sialophosphoprotein | 0.0492927 |
| MSN | moesin | 0.0480724 |
| RPS2 | ribosomal protein S2 | 0.0478576 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0478552 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0464731 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0464047 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.046332 |
| PTMA | prothymosin, alpha | 0.0460281 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0447871 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0445242 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0437327 |
| FLNB | filamin B, beta | 0.0436984 |
| KRT18 | keratin 18, type I | 0.043445 |
| TMF1 | TATA element modulatory factor 1 | 0.0433057 |
| RPL8 | ribosomal protein L8 | 0.0430121 |
| RPS13 | ribosomal protein S13 | 0.0426013 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.04252 |
| PTK2 | protein tyrosine kinase 2 | 0.0421045 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0420947 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0412165 |
| ZNF292 | zinc finger protein 292 | 0.0405547 |
| FHIT | fragile histidine triad | 0.0396119 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0389961 |
| RPL37A | ribosomal protein L37a | 0.0389891 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0389559 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0389296 |
| RPS29 | ribosomal protein S29 | 0.0383712 |
| RPL7 | ribosomal protein L7 | 0.0379386 |
| MKI67 | marker of proliferation Ki-67 | 0.03791 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.037595 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0370797 |
| OGA | O-GlcNAcase | 0.0368163 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.036723 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0367012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0365684 |
| FBXO32 | F-box protein 32 | 0.0361976 |
| HDGF | hepatoma-derived growth factor | 0.0358669 |
| ADAR | adenosine deaminase, RNA-specific | 0.0358564 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0358236 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0356881 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0349718 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0345057 |
| CENPF | centromere protein F, 350/400kDa | 0.0343521 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0340837 |
| UPP1 | uridine phosphorylase 1 | 0.0340248 |
| CTTN | cortactin | 0.0337555 |
| PLEC | plectin | 0.0329742 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0329165 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0328104 |
| CCNY | cyclin Y | 0.0325381 |
| RPL9 | ribosomal protein L9 | 0.0319477 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0318356 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0308802 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0305272 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0302248 |
| NCKAP1 | NCK-associated protein 1 | 0.0301182 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0300904 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0300604 |
| DST | dystonin | 0.0299957 |
| ENO1 | enolase 1, (alpha) | 0.0294681 |
| MXD1 | MAX dimerization protein 1 | 0.0292655 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0291959 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0291576 |
| YBX1 | Y box binding protein 1 | 0.0291423 |
| RPLP2 | ribosomal protein, large, P2 | 0.0291198 |
| PDE8A | phosphodiesterase 8A | 0.0289486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149481 |
| FTL | ferritin, light polypeptide | -0.139836 |
| TMSB10 | thymosin beta 10 | -0.110817 |
| LMO7 | LIM domain 7 | -0.0860873 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.07796 |
| FN1 | fibronectin 1 | -0.0719666 |
| RPLP1 | ribosomal protein, large, P1 | -0.0614569 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0603339 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0563817 |
| POTEF | POTE ankyrin domain family, member F | -0.0559656 |
| ERBIN | erbb2 interacting protein | -0.0529831 |
| CCND1 | cyclin D1 | -0.0482994 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0466587 |
| ARF1 | ADP-ribosylation factor 1 | -0.0453068 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0412037 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0406997 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0394847 |
| S100A6 | S100 calcium binding protein A6 | -0.0381199 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0375252 |
| ACTG1 | actin gamma 1 | -0.0360224 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0358532 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0358376 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0345807 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0344787 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336413 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0319766 |
| RPS24 | ribosomal protein S24 | -0.0311068 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0306876 |
| RPL27A | ribosomal protein L27a | -0.0302228 |
| RASAL2 | RAS protein activator like 2 | -0.030222 |
| RPL4 | ribosomal protein L4 | -0.0299205 |
| OSMR | oncostatin M receptor | -0.0297214 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0295038 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0291733 |
| EGFR | epidermal growth factor receptor | -0.0287797 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0269786 |
| RHOA | ras homolog family member A | -0.0268064 |
| TMEM165 | transmembrane protein 165 | -0.0266633 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0259181 |
| TPM4 | tropomyosin 4 | -0.0258114 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0246818 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0243605 |
| MGLL | monoglyceride lipase | -0.0242801 |
| EGR1 | early growth response 1 | -0.0241664 |
| NRP1 | neuropilin 1 | -0.0234928 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0228876 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0227487 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0226793 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0225774 |
| GNAS | GNAS complex locus | -0.0222858 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0222 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.022038 |
| REEP3 | receptor accessory protein 3 | -0.0219793 |
| CTSD | cathepsin D | -0.0217885 |
| TJP1 | tight junction protein 1 | -0.0217678 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0217384 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0217132 |
| FAM3C | family with sequence similarity 3, member C | -0.0213224 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0206706 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0206675 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0204861 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0203125 |
| RPL35A | ribosomal protein L35a | -0.0201764 |
| ZNF207 | zinc finger protein 207 | -0.0200927 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.020027 |
| USP15 | ubiquitin specific peptidase 15 | -0.0198588 |
| FBXO11 | F-box protein 11 | -0.0194961 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0194308 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0193489 |
| CEP350 | centrosomal protein 350kDa | -0.0192379 |
| SP100 | SP100 nuclear antigen | -0.0192241 |
| UBAP1 | ubiquitin associated protein 1 | -0.0191731 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0189696 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0189289 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.018848 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0185735 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0185389 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0185236 |
| OCLN | occludin | -0.0180942 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0179058 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0178862 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0174204 |
| COPA | coatomer protein complex, subunit alpha | -0.0171974 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0171908 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0164677 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0164306 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0163283 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0162765 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0162209 |
| CAVIN1 | caveolae associated protein 1 | -0.0160745 |
| ANXA2 | annexin A2 | -0.0159695 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0158752 |
| VIM | vimentin | -0.0158559 |
| NEMF | nuclear export mediator factor | -0.0158431 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0156647 |
| HDLBP | high density lipoprotein binding protein | -0.0156642 |
| S100A10 | S100 calcium binding protein A10 | -0.0156236 |
| TOP1 | topoisomerase (DNA) I | -0.0156077 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0155965 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0155384 |
