| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0917481 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.076771 |
| DST | dystonin | 0.0722813 |
| RPS6 | ribosomal protein S6 | 0.0604669 |
| FAM13A | family with sequence similarity 13, member A | 0.0592349 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0571968 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0528164 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0526582 |
| TBXT | T-box transcription factor T | 0.0447975 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0446242 |
| MKI67 | marker of proliferation Ki-67 | 0.0418193 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0410912 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0410495 |
| FLNB | filamin B, beta | 0.0408932 |
| ARRDC3 | arrestin domain containing 3 | 0.0380686 |
| MSN | moesin | 0.037081 |
| PRELID2 | PRELI domain containing 2 | 0.0367999 |
| NDRG1 | N-myc downstream regulated 1 | 0.0362638 |
| RPS2 | ribosomal protein S2 | 0.0343537 |
| GPC6 | glypican 6 | 0.033905 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0338948 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0330922 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0326924 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0320934 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0320845 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0319707 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308064 |
| PHF21A | PHD finger protein 21A | 0.0308004 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0304208 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0303863 |
| CENPF | centromere protein F, 350/400kDa | 0.0303031 |
| MFF | mitochondrial fission factor | 0.0300758 |
| LAMB1 | laminin, beta 1 | 0.0300296 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0294234 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0291365 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0288956 |
| GOLGA4 | golgin A4 | 0.0287773 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0287434 |
| AUTS2 | autism susceptibility candidate 2 | 0.028429 |
| CTSL | cathepsin L | 0.0279021 |
| TPM3 | tropomyosin 3 | 0.0275541 |
| ZNF292 | zinc finger protein 292 | 0.0271404 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271266 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0270701 |
| HELZ | helicase with zinc finger | 0.0269941 |
| OGA | O-GlcNAcase | 0.0266749 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.026429 |
| RPS19 | ribosomal protein S19 | 0.0260951 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0258614 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0257635 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.025424 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0251045 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0248431 |
| VEGFA | vascular endothelial growth factor A | 0.0248384 |
| PTMA | prothymosin, alpha | 0.0244516 |
| SLK | STE20-like kinase | 0.0242615 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0238596 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0238146 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0236003 |
| RGS2 | regulator of G-protein signaling 2 | 0.0234474 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0231472 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0229797 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0229032 |
| PRKD3 | protein kinase D3 | 0.0228139 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0227786 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0226699 |
| CRLF2 | cytokine receptor-like factor 2 | 0.022546 |
| RNF145 | ring finger protein 145 | 0.0225005 |
| SRPK2 | SRSF protein kinase 2 | 0.0222709 |
| SFTPA2 | surfactant protein A2 | 0.0222497 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0222057 |
| TMF1 | TATA element modulatory factor 1 | 0.0217338 |
| CTBP2 | C-terminal binding protein 2 | 0.0215829 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0215773 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0215723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0215037 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0214271 |
| RPL3 | ribosomal protein L3 | 0.0213485 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0210913 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0209553 |
| SETD5 | SET domain containing 5 | 0.0207042 |
| CEP170 | centrosomal protein 170kDa | 0.0206137 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0206067 |
| PCBP3 | poly(rC) binding protein 3 | 0.0205787 |
| FAM219A | family with sequence similarity 219, member A | 0.0204523 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0203422 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0202647 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.020217 |
| ITGA6 | integrin, alpha 6 | 0.0201757 |
| VMP1 | vacuole membrane protein 1 | 0.0201709 |
| RBM39 | RNA binding motif protein 39 | 0.0200198 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0199598 |
| NBAS | neuroblastoma amplified sequence | 0.019936 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0197621 |
| TXNIP | thioredoxin interacting protein | 0.0197574 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0196645 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0196413 |
| H1-4 | H1.4 linker histone, cluster member | 0.0195836 |
| TENM3 | teneurin transmembrane protein 3 | 0.0194676 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0194006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.337427 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.189936 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.160322 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.1254 |
| GDA | guanine deaminase | -0.108229 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0920229 |
| VIM | vimentin | -0.0919799 |
| TXNRD1 | thioredoxin reductase 1 | -0.0869209 |
| CANX | calnexin | -0.0825968 |
| RPS24 | ribosomal protein S24 | -0.0796517 |
| KYNU | kynureninase | -0.0773576 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0773098 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0727444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0704335 |
| ASPH | aspartate beta-hydroxylase | -0.0672906 |
| COL5A2 | collagen, type V, alpha 2 | -0.0647727 |
| LDHA | lactate dehydrogenase A | -0.0646644 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0638091 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0604515 |
| FN1 | fibronectin 1 | -0.0595394 |
| PDE10A | phosphodiesterase 10A | -0.0586563 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0585714 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0578172 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.057744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0560801 |
| PGK1 | phosphoglycerate kinase 1 | -0.0560526 |
| MYOF | myoferlin | -0.0540057 |
| RPL4 | ribosomal protein L4 | -0.0522641 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0509658 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0508159 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0504187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0493706 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0490978 |
| ACTG1 | actin gamma 1 | -0.0490779 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.048036 |
| VCL | vinculin | -0.0474291 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0469647 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0463478 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0462363 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0457817 |
| RPL35A | ribosomal protein L35a | -0.0449221 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0446433 |
| MORF4L2 | mortality factor 4 like 2 | -0.0445872 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0443005 |
| RPLP0 | ribosomal protein, large, P0 | -0.0435881 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.041887 |
| RPLP1 | ribosomal protein, large, P1 | -0.0417268 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0417018 |
| ANTXR1 | anthrax toxin receptor 1 | -0.040806 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0400117 |
| SMYD3 | SET and MYND domain containing 3 | -0.0393489 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0391714 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0385948 |
| FTL | ferritin, light polypeptide | -0.0384975 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0381902 |
| SQSTM1 | sequestosome 1 | -0.0381633 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0381055 |
| ARF1 | ADP-ribosylation factor 1 | -0.0367594 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0359473 |
| TNPO1 | transportin 1 | -0.0356262 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0351292 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0347469 |
| CDH13 | cadherin 13 | -0.034224 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.033738 |
| ENO1 | enolase 1, (alpha) | -0.0320938 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0317069 |
| RPL12 | ribosomal protein L12 | -0.0315394 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0311237 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0306927 |
| TKT | transketolase | -0.0306855 |
| PCBP2 | poly(rC) binding protein 2 | -0.0298905 |
| HDLBP | high density lipoprotein binding protein | -0.0298029 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0296282 |
| LAMA1 | laminin, alpha 1 | -0.0296234 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0296112 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0291837 |
| PLCB4 | phospholipase C, beta 4 | -0.0289677 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.028916 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0289026 |
| RHOB | ras homolog family member B | -0.0280715 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0279999 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0279537 |
| RPL39 | ribosomal protein L39 | -0.0279443 |
| GNAS | GNAS complex locus | -0.0278904 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275018 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273189 |
| SMAD2 | SMAD family member 2 | -0.0267183 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0266211 |
| ANXA2 | annexin A2 | -0.0260285 |
| S100A6 | S100 calcium binding protein A6 | -0.0258472 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0256462 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0255981 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0254945 |
| RPS20 | ribosomal protein S20 | -0.0253325 |
| ENAH | enabled homolog (Drosophila) | -0.0252354 |
| EGR1 | early growth response 1 | -0.0250747 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0250713 |
| SPAG9 | sperm associated antigen 9 | -0.0249835 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0244118 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0242626 |
