| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.100369 |
| NTM | neurotrimin | 0.0849433 |
| PTMA | prothymosin, alpha | 0.0727624 |
| CALR | calreticulin | 0.0658588 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.060563 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.057858 |
| NCKAP1 | NCK-associated protein 1 | 0.057765 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0570056 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.056681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0564642 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0558999 |
| MKI67 | marker of proliferation Ki-67 | 0.0549752 |
| RPS12 | ribosomal protein S12 | 0.0525395 |
| PHIP | pleckstrin homology domain interacting protein | 0.0523703 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0510641 |
| H1-4 | H1.4 linker histone, cluster member | 0.0500588 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0495447 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0488923 |
| USP53 | ubiquitin specific peptidase 53 | 0.0479682 |
| MB21D2 | Mab-21 domain containing 2 | 0.0452958 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.045177 |
| TPR | translocated promoter region, nuclear basket protein | 0.0447952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0447934 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.042649 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.042374 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0418091 |
| ANXA1 | annexin A1 | 0.0411144 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0404357 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0393855 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0393553 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.039149 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0386878 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378217 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0367834 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0365287 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0362526 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0361818 |
| PDS5A | PDS5 cohesin associated factor A | 0.0361127 |
| FUS | FUS RNA binding protein | 0.03528 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0344983 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0344243 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336049 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0334446 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331374 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.032586 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0325668 |
| SPAG5 | sperm associated antigen 5 | 0.0324919 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0319056 |
| APP | amyloid beta (A4) precursor protein | 0.0314724 |
| TPM3 | tropomyosin 3 | 0.0308177 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0303259 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0299691 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0298744 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0297866 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0296161 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.029518 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0294321 |
| POU2F1 | POU class 2 homeobox 1 | 0.0292062 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0291363 |
| MYO10 | myosin X | 0.0286688 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0285894 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0285137 |
| RPS2 | ribosomal protein S2 | 0.0285108 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0282355 |
| CRY1 | cryptochrome circadian clock 1 | 0.0280266 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0279852 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0279549 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0278143 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0276857 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0275739 |
| MEF2A | myocyte enhancer factor 2A | 0.0273254 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0272875 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 0.0270812 |
| PDE8A | phosphodiesterase 8A | 0.0270651 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0269056 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0268783 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0267923 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0266119 |
| SLK | STE20-like kinase | 0.0266115 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0264078 |
| STMN1 | stathmin 1 | 0.0262113 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0260409 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0260055 |
| MCL1 | myeloid cell leukemia 1 | 0.0259329 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0257887 |
| ZNF292 | zinc finger protein 292 | 0.0257485 |
| NUP153 | nucleoporin 153kDa | 0.0256756 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0255999 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0255261 |
| SFTPA2 | surfactant protein A2 | 0.0253563 |
| DST | dystonin | 0.0253336 |
| FMNL2 | formin-like 2 | 0.0253292 |
| RPS3 | ribosomal protein S3 | 0.0253124 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.0253007 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0252847 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0252571 |
| RPL10A | ribosomal protein L10a | 0.0251733 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0251061 |
| SPAG9 | sperm associated antigen 9 | 0.0249499 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0248883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.224775 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0897495 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0831627 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0824052 |
| CADM2 | cell adhesion molecule 2 | -0.0809648 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.078182 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0755496 |
| POTEF | POTE ankyrin domain family, member F | -0.0720991 |
| PEG10 | paternally expressed 10 | -0.0715735 |
| RPLP1 | ribosomal protein, large, P1 | -0.071121 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0673269 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0658124 |
| TENM3 | teneurin transmembrane protein 3 | -0.0657948 |
| ACTG1 | actin gamma 1 | -0.0652001 |
| TMSB10 | thymosin beta 10 | -0.0592982 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0584374 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0573459 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0551193 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0528437 |
| TXNRD1 | thioredoxin reductase 1 | -0.0483288 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0468987 |
| FTL | ferritin, light polypeptide | -0.0463444 |
| RPL35A | ribosomal protein L35a | -0.0455849 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0454512 |
| LDHA | lactate dehydrogenase A | -0.0447086 |
| PCBP2 | poly(rC) binding protein 2 | -0.0443294 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.04326 |
| HMGA2 | high mobility group AT-hook 2 | -0.0426017 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0406483 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0404553 |
| LMAN1 | lectin, mannose-binding, 1 | -0.040287 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0402322 |
| AHNAK | AHNAK nucleoprotein | -0.0401742 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0401731 |
| HMGA1 | high mobility group AT-hook 1 | -0.0400064 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397768 |
| DEK | DEK proto-oncogene | -0.039601 |
| COL5A2 | collagen, type V, alpha 2 | -0.0390569 |
| NF1 | neurofibromin 1 | -0.0388068 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0386259 |
| ENO1 | enolase 1, (alpha) | -0.0385345 |
| RPL23 | ribosomal protein L23 | -0.0381728 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0369263 |
| SYT1 | synaptotagmin I | -0.0367677 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361203 |
| ABI2 | abl-interactor 2 | -0.0360053 |
| RPS24 | ribosomal protein S24 | -0.0355894 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0354966 |
| H1-0 | H1.0 linker histone | -0.0352772 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0351144 |
| TUBA1B | tubulin, alpha 1b | -0.0348924 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.034484 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0343262 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0342539 |
| RPLP0 | ribosomal protein, large, P0 | -0.0340631 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0340478 |
| GPC3 | glypican 3 | -0.033576 |
| DSTN | destrin (actin depolymerizing factor) | -0.033542 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0335285 |
| TMEM165 | transmembrane protein 165 | -0.0334271 |
| HMGB1 | high mobility group box 1 | -0.0327871 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0324844 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0324819 |
| RPL31 | ribosomal protein L31 | -0.0324641 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0322051 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0319442 |
| MAP1B | microtubule-associated protein 1B | -0.0319003 |
| IPO7 | importin 7 | -0.0318543 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0317667 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0315935 |
| GNAS | GNAS complex locus | -0.0314578 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0312727 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0311579 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0309029 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0308722 |
| FOXP2 | forkhead box P2 | -0.0308632 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.030306 |
| FN1 | fibronectin 1 | -0.0302854 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0302208 |
| RAB31 | RAB31, member RAS oncogene family | -0.0300569 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.029815 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.029614 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0292859 |
| LYPLA1 | lysophospholipase I | -0.0292418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0291887 |
| MED13L | mediator complex subunit 13-like | -0.0291546 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0289455 |
| SGO2 | shugoshin 2 | -0.0286075 |
| FIGN | fidgetin | -0.0285685 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0285645 |
| JMJD1C | jumonji domain containing 1C | -0.0284683 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028448 |
| NUP155 | nucleoporin 155kDa | -0.02829 |
| B2M | beta-2-microglobulin | -0.0282264 |
| USP34 | ubiquitin specific peptidase 34 | -0.0280755 |
| PHF6 | PHD finger protein 6 | -0.0277608 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0276266 |
| RHOA | ras homolog family member A | -0.0275745 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.02746 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0270436 |
