Daidzin_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Daidzin perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Daidzin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.155081
EZR ezrin 0.114844
FLNB filamin B, beta 0.104013
PDE4D phosphodiesterase 4D, cAMP-specific 0.0994768
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0908016
EEF2 eukaryotic translation elongation factor 2 0.0713417
RPL3 ribosomal protein L3 0.0682066
TXNRD1 thioredoxin reductase 1 0.064657
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0640044
HDAC9 histone deacetylase 9 0.061582
SOX6 SRY (sex determining region Y)-box 6 0.0613825
ENO2 enolase 2 (gamma, neuronal) 0.0601195
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0592143
CENPF centromere protein F, 350/400kDa 0.0510751
ADAM10 ADAM metallopeptidase domain 10 0.0507036
LPP LIM domain containing preferred translocation partner in lipoma 0.0490073
AKAP9 A kinase (PRKA) anchor protein 9 0.047922
SRRM2 serine/arginine repetitive matrix 2 0.0475231
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0472016
ANXA1 annexin A1 0.0463682
GOLGA4 golgin A4 0.0457733
RPS2 ribosomal protein S2 0.0452975
EEF1G eukaryotic translation elongation factor 1 gamma 0.0450873
PICALM phosphatidylinositol binding clathrin assembly protein 0.0449928
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0436693
SBF2 SET binding factor 2 0.0419448
PCBP2 poly(rC) binding protein 2 0.0410759
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0399922
RPS12 ribosomal protein S12 0.0396763
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0390049
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0387285
NBAS neuroblastoma amplified sequence 0.0377683
VEGFA vascular endothelial growth factor A 0.0367651
PKM pyruvate kinase, muscle 0.0359016
ZNF608 zinc finger protein 608 0.0358134
SFPQ splicing factor proline/glutamine-rich 0.0357455
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0355632
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0352655
RPS6 ribosomal protein S6 0.0346239
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0346158
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0345405
N4BP2L2 NEDD4 binding protein 2-like 2 0.0338959
DSCAM Down syndrome cell adhesion molecule 0.0335102
TMF1 TATA element modulatory factor 1 0.0332249
FAT1 FAT atypical cadherin 1 0.0330284
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0326318
MACF1 microtubule-actin crosslinking factor 1 0.0323072
SMYD3 SET and MYND domain containing 3 0.0322525
EIF4B eukaryotic translation initiation factor 4B 0.0321684
ANKRD36 ankyrin repeat domain 36 0.0320631
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0320425
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.0319894
SETD5 SET domain containing 5 0.0319213
PRRC2C proline-rich coiled-coil 2C 0.0315799
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0313681
GOLGB1 golgin B1 0.0309753
KTN1 kinectin 1 (kinesin receptor) 0.0307531
EGFR epidermal growth factor receptor 0.0306533
ECPAS Ecm29 proteasome adaptor and scaffold 0.0305978
SLC38A2 solute carrier family 38, member 2 0.0302816
ASPH aspartate beta-hydroxylase 0.0301516
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0297521
PRELID2 PRELI domain containing 2 0.0296511
FNIP1 folliculin interacting protein 1 0.0293022
VMP1 vacuole membrane protein 1 0.0292878
PLXNA1 plexin A1 0.0291762
RPL37A ribosomal protein L37a 0.0290281
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0288596
YAP1 Yes-associated protein 1 0.0288252
PDGFC platelet derived growth factor C 0.0287762
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.0284587
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0280312
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0276794
NPAS2 neuronal PAS domain protein 2 0.027369
POTEF POTE ankyrin domain family, member F 0.0272634
BIRC6 baculoviral IAP repeat containing 6 0.0272101
FNDC3B fibronectin type III domain containing 3B 0.0271724
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0271501
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0267168
DLG1 discs, large homolog 1 (Drosophila) 0.0267099
CCNY cyclin Y 0.0266166
SAMD4A sterile alpha motif domain containing 4A 0.0264628
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.026417
SUCO SUN domain containing ossification factor 0.0262961
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0262782
RAD23B RAD23 homolog B (S. cerevisiae) 0.0262513
GSE1 Gse1 coiled-coil protein 0.0260785
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.025674
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.025602
RPL21 ribosomal protein L21 0.0253602
SET SET nuclear proto-oncogene 0.0251076
KMT2D lysine (K)-specific methyltransferase 2D 0.0250653
GYS1 glycogen synthase 1 (muscle) 0.0250521
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0250465
AMOTL2 angiomotin like 2 0.0249323
TBC1D22A TBC1 domain family, member 22A 0.0247589
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0246467
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0245047
RPL11 ribosomal protein L11 0.0244746
PDE4B phosphodiesterase 4B, cAMP-specific 0.0244437

decreased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.265326
TPT1 tumor protein, translationally-controlled 1 -0.101738
AHNAK AHNAK nucleoprotein -0.0916483
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0649656
TMSB4X thymosin beta 4, X-linked -0.0571668
S100A6 S100 calcium binding protein A6 -0.0564782
SSBP2 single-stranded DNA binding protein 2 -0.0488309
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0473701
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0463925
BMP10 bone morphogenetic protein 10 -0.0463747
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0442555
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0440914
PTMA prothymosin, alpha -0.0435592
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0430611
RPL35A ribosomal protein L35a -0.0409389
ACTG1 actin gamma 1 -0.0383945
RPS24 ribosomal protein S24 -0.0380895
GARS1 glycyl-tRNA synthetase 1 -0.0373081
RPLP1 ribosomal protein, large, P1 -0.0353763
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0352475
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0350466
LOC112694756 uncharaterized LOC112694756 -0.0328736
EIF4A2 eukaryotic translation initiation factor 4A2 -0.0315826
IFI16 interferon, gamma-inducible protein 16 -0.0310977
S100A4 S100 calcium binding protein A4 -0.0310394
CCNI cyclin I -0.0306945
NAP1L1 nucleosome assembly protein 1-like 1 -0.0306527
HSPH1 heat shock 105kDa/110kDa protein 1 -0.029645
CANX calnexin -0.0295271
VDAC1 voltage-dependent anion channel 1 -0.028334
FTL ferritin, light polypeptide -0.0274801
STAU1 staufen double-stranded RNA binding protein 1 -0.0271665
RPL13A ribosomal protein L13a -0.0270672
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0268357
ABI1 abl-interactor 1 -0.0267746
EML4 echinoderm microtubule associated protein like 4 -0.0266617
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0253489
NSD3 nuclear receptor binding SET domain protein 3 -0.0252399
RSL1D1 ribosomal L1 domain containing 1 -0.024959
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0248422
RBM39 RNA binding motif protein 39 -0.0247237
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0245783
IFI6 interferon, alpha-inducible protein 6 -0.0243297
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0241456
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0238105
RPL32 ribosomal protein L32 -0.0235078
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0232972
ZFAND3 zinc finger, AN1-type domain 3 -0.0230493
WSB1 WD repeat and SOCS box containing 1 -0.0229271
MZT1 mitotic spindle organizing protein 1 -0.0228292
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.0227568
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0227041
FOXP1 forkhead box P1 -0.0225774
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0224343
LMAN1 lectin, mannose-binding, 1 -0.0223053
MIPOL1 mirror-image polydactyly 1 -0.0221664
RPLP0 ribosomal protein, large, P0 -0.0220133
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0219745
RPS27A ribosomal protein S27a -0.0219378
H3-3B H3.3 histone B -0.0217906
SRP72 signal recognition particle 72kDa -0.0216857
RAB1A RAB1A, member RAS oncogene family -0.0213554
ZMYND8 zinc finger, MYND-type containing 8 -0.0213038
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0212984
RHEB Ras homolog enriched in brain -0.0210424
EIF1 eukaryotic translation initiation factor 1 -0.0209553
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0207373
ARF1 ADP-ribosylation factor 1 -0.0207368
CENATAC centrosomal AT-AC splicing factor -0.0206547
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0205349
SDCBP syndecan binding protein (syntenin) -0.0204917
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0203106
LCORL ligand dependent nuclear receptor corepressor-like -0.0198907
ANKRD10 ankyrin repeat domain 10 -0.0198104
TUBB tubulin, beta class I -0.0195515
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0194895
RIGI RNA sensor RIG-I -0.0194042
B2M beta-2-microglobulin -0.0193781
NAV2 neuron navigator 2 -0.0192721
DUSP6 dual specificity phosphatase 6 -0.0191691
CAMKMT calmodulin-lysine N-methyltransferase -0.0190006
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0189602
BCOR BCL6 corepressor -0.0187853
RRBP1 ribosome binding protein 1 -0.018707
ANTXR1 anthrax toxin receptor 1 -0.018514
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0184931
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0184917
RPL4 ribosomal protein L4 -0.0184859
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.018427
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0183844
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.0183296
PIAS1 protein inhibitor of activated STAT, 1 -0.0181633
ANKRD17 ankyrin repeat domain 17 -0.0180998
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0177953
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0177568
HSPB1 heat shock 27kDa protein 1 -0.0177084
HDLBP high density lipoprotein binding protein -0.0175236
IARS1 isoleucyl-tRNA synthetase 1 -0.0174948
RSRC1 arginine/serine-rich coiled-coil 1 -0.0174903
PDIA4 protein disulfide isomerase family A, member 4 -0.0174877