| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daidzin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daidzin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.11391 |
| VEGFA | vascular endothelial growth factor A | 0.0855376 |
| NDRG1 | N-myc downstream regulated 1 | 0.0851868 |
| TXNIP | thioredoxin interacting protein | 0.0712684 |
| SFTPA2 | surfactant protein A2 | 0.0660363 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0604377 |
| FAM13A | family with sequence similarity 13, member A | 0.0556937 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.055323 |
| GOLGA4 | golgin A4 | 0.0525221 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0523381 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0504976 |
| TPR | translocated promoter region, nuclear basket protein | 0.05048 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0498372 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0493617 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0492385 |
| MKI67 | marker of proliferation Ki-67 | 0.0464684 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0459887 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0458887 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0444271 |
| TMF1 | TATA element modulatory factor 1 | 0.0423797 |
| SUCO | SUN domain containing ossification factor | 0.0407385 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0407251 |
| PRELID2 | PRELI domain containing 2 | 0.0403529 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0400492 |
| PTMA | prothymosin, alpha | 0.0391173 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0386154 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.036881 |
| STC2 | stanniocalcin 2 | 0.0363085 |
| B2M | beta-2-microglobulin | 0.0361557 |
| CD109 | CD109 molecule | 0.0357694 |
| VEGFC | vascular endothelial growth factor C | 0.0354645 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0347118 |
| DST | dystonin | 0.0347037 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0343311 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0340719 |
| ZNF292 | zinc finger protein 292 | 0.0339311 |
| HDGF | hepatoma-derived growth factor | 0.0336459 |
| OGA | O-GlcNAcase | 0.0322922 |
| RPS27 | ribosomal protein S27 | 0.0315333 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0313603 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0313301 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.030392 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0303657 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0303415 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0300809 |
| RPL11 | ribosomal protein L11 | 0.0300761 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0300326 |
| ARRDC3 | arrestin domain containing 3 | 0.0299507 |
| RPS6 | ribosomal protein S6 | 0.0297429 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0295264 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0294171 |
| GOLT1B | golgi transport 1B | 0.0292375 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.029195 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0289329 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0288052 |
| CUL3 | cullin 3 | 0.0286186 |
| CDC73 | cell division cycle 73 | 0.027818 |
| RPL3 | ribosomal protein L3 | 0.0276643 |
| CENPF | centromere protein F, 350/400kDa | 0.0276413 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0275525 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0268458 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0264299 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0261216 |
| PNN | pinin, desmosome associated protein | 0.0258612 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0257836 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0257302 |
| ZNF146 | zinc finger protein 146 | 0.0256918 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0256897 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0253673 |
| FNBP1 | formin binding protein 1 | 0.0253606 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0252653 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.024758 |
| TMSB10 | thymosin beta 10 | 0.0247326 |
| CAB39 | calcium binding protein 39 | 0.0246211 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.023784 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0235431 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0234851 |
| RBM25 | RNA binding motif protein 25 | 0.023341 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0230845 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0229209 |
| ZNF160 | zinc finger protein 160 | 0.0229106 |
| SDE2 | SDE2 telomere maintenance homolog (S. pombe) | 0.0228892 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0227685 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0226206 |
| HMGB3 | high mobility group box 3 | 0.0222701 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0222545 |
| SQSTM1 | sequestosome 1 | 0.0221143 |
| RNF115 | ring finger protein 115 | 0.0220159 |
| RPS29 | ribosomal protein S29 | 0.0219058 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0217587 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0215595 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0214326 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213003 |
| S100A9 | S100 calcium binding protein A9 | 0.021286 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0211657 |
| FLNB | filamin B, beta | 0.0209466 |
| RPS21 | ribosomal protein S21 | 0.0209192 |
| MSN | moesin | 0.0208556 |
| RPL37A | ribosomal protein L37a | 0.0208097 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.020658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.283669 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.16129 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.144525 |
| FN1 | fibronectin 1 | -0.14018 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111904 |
| HMGA2 | high mobility group AT-hook 2 | -0.111337 |
| NRG1 | neuregulin 1 | -0.102205 |
| VIM | vimentin | -0.0925651 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0775902 |
| CANX | calnexin | -0.0702324 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.057261 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0565377 |
| INTS6 | integrator complex subunit 6 | -0.0555475 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0524042 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0497567 |
| RPS24 | ribosomal protein S24 | -0.0478851 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0469021 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0463773 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0441332 |
| ARF1 | ADP-ribosylation factor 1 | -0.0430969 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0420913 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0416903 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041549 |
| SEPTIN7 | septin 7 | -0.0415099 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0411389 |
| IL6ST | interleukin 6 signal transducer | -0.0407039 |
| PCBP2 | poly(rC) binding protein 2 | -0.0398929 |
| IER3 | immediate early response 3 | -0.0377755 |
| HMGA1 | high mobility group AT-hook 1 | -0.0376329 |
| EFNA5 | ephrin-A5 | -0.0373854 |
| AHR | aryl hydrocarbon receptor | -0.0369831 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356296 |
| WDR45B | WD repeat domain 45B | -0.0354546 |
| LRRC23 | leucine rich repeat containing 23 | -0.0353203 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0352915 |
| RPLP0 | ribosomal protein, large, P0 | -0.0351299 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0343326 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0341542 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0340453 |
| PALLD | palladin, cytoskeletal associated protein | -0.0340295 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0330844 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0327641 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0325779 |
| ACTG1 | actin gamma 1 | -0.0319104 |
| CADM1 | cell adhesion molecule 1 | -0.0318591 |
| TMEM165 | transmembrane protein 165 | -0.0316862 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0315551 |
| RPS25 | ribosomal protein S25 | -0.031455 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.031153 |
| SDCBP | syndecan binding protein (syntenin) | -0.0309826 |
| GNAS | GNAS complex locus | -0.0308799 |
| DSTN | destrin (actin depolymerizing factor) | -0.0305132 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0298302 |
| TFG | TRK-fused gene | -0.0290196 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0287138 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0284465 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0280101 |
| RHOA | ras homolog family member A | -0.027983 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0274784 |
| RPS16 | ribosomal protein S16 | -0.0270855 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.027074 |
| IL6 | interleukin 6 | -0.0265846 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.026393 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0263733 |
| BSG | basigin (Ok blood group) | -0.0261931 |
| PARD3 | par-3 family cell polarity regulator | -0.0259742 |
| POTEF | POTE ankyrin domain family, member F | -0.0259226 |
| TPM4 | tropomyosin 4 | -0.0254792 |
| NUP58 | nucleoporin 58 | -0.025272 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0250976 |
| RPL35A | ribosomal protein L35a | -0.0248544 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0248146 |
| ODR4 | odr-4 GPCR localization factor homolog | -0.0247467 |
| FLNA | filamin A, alpha | -0.0246302 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0246102 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0237812 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.023553 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.023522 |
| RPL12 | ribosomal protein L12 | -0.0231591 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0231197 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0230124 |
| MTSS1 | metastasis suppressor 1 | -0.0228698 |
| AEBP2 | AE binding protein 2 | -0.0227156 |
| GLIS3 | GLIS family zinc finger 3 | -0.0226983 |
| RYBP | RING1 and YY1 binding protein | -0.0224592 |
| PTK2 | protein tyrosine kinase 2 | -0.0224251 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0222901 |
| ATP11B | ATPase, class VI, type 11B | -0.0222442 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0220416 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0219703 |
| USP34 | ubiquitin specific peptidase 34 | -0.0219096 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0218839 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0215779 |
| TMEM131 | transmembrane protein 131 | -0.0215624 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0215249 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0214143 |
| TMEM123 | transmembrane protein 123 | -0.0213493 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0213311 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0213245 |