| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.123411 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0729911 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0636755 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.063377 |
| MED13L | mediator complex subunit 13-like | 0.0455645 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0447053 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0446859 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0416385 |
| RNF130 | ring finger protein 130 | 0.040365 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0401754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0393568 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0375078 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.037095 |
| RAD51B | RAD51 paralog B | 0.0367751 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0359949 |
| DENND1A | DENN/MADD domain containing 1A | 0.0356421 |
| RPS18 | ribosomal protein S18 | 0.034252 |
| PTK2 | protein tyrosine kinase 2 | 0.0329132 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0327711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321888 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0319968 |
| APP | amyloid beta (A4) precursor protein | 0.0315103 |
| MGP | matrix Gla protein | 0.0314417 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0312732 |
| AHNAK | AHNAK nucleoprotein | 0.0311571 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0311316 |
| TFG | TRK-fused gene | 0.0303171 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0302328 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.030095 |
| KIF1A | kinesin family member 1A | 0.0295368 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0289134 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0288605 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0286062 |
| CCNY | cyclin Y | 0.0284468 |
| QKI | QKI, KH domain containing, RNA binding | 0.0282446 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.028072 |
| LOXL2 | lysyl oxidase-like 2 | 0.0278758 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0275512 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0273203 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272798 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0270816 |
| HSPB1 | heat shock 27kDa protein 1 | 0.026914 |
| COL1A2 | collagen, type I, alpha 2 | 0.0267229 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0265808 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0264472 |
| MSRA | methionine sulfoxide reductase A | 0.0264154 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0258912 |
| CD164 | CD164 molecule, sialomucin | 0.0258659 |
| MYOF | myoferlin | 0.0258148 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.025656 |
| FN1 | fibronectin 1 | 0.025215 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0251847 |
| CASC3 | cancer susceptibility candidate 3 | 0.0251794 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0251113 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0248758 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.024821 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0247458 |
| MEMO1 | mediator of cell motility 1 | 0.0240769 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0238011 |
| CREBRF | CREB3 regulatory factor | 0.0234718 |
| FMNL2 | formin-like 2 | 0.0234592 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0233335 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0230835 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0230531 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0230181 |
| RNF145 | ring finger protein 145 | 0.0223738 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0223181 |
| XPO6 | exportin 6 | 0.0221146 |
| SGMS1 | sphingomyelin synthase 1 | 0.0220844 |
| RBM26 | RNA binding motif protein 26 | 0.0220731 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0220428 |
| GSE1 | Gse1 coiled-coil protein | 0.0219814 |
| CCNL1 | cyclin L1 | 0.0219305 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0218834 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0218653 |
| PLS3 | plastin 3 | 0.021766 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0217038 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0217018 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0216698 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0216524 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0215384 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0214881 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0214074 |
| RPL3 | ribosomal protein L3 | 0.0213537 |
| ADD1 | adducin 1 (alpha) | 0.0211987 |
| ERI3 | ERI1 exoribonuclease family member 3 | 0.0211564 |
| RREB1 | ras responsive element binding protein 1 | 0.0209732 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0208426 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0208345 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0205417 |
| ABI1 | abl-interactor 1 | 0.0205151 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0204984 |
| INHBA | inhibin, beta A | 0.0202998 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0201003 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0200734 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0200561 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0199975 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0199866 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0199708 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0199592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16649 |
| MEST | mesoderm specific transcript | -0.165309 |
| VIM | vimentin | -0.158486 |
| MT2A | metallothionein 2A | -0.111266 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.103537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0833175 |
| RPS2 | ribosomal protein S2 | -0.082505 |
| RPS6 | ribosomal protein S6 | -0.0823104 |
| CENPF | centromere protein F, 350/400kDa | -0.0807763 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0642389 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0634124 |
| SBF2 | SET binding factor 2 | -0.0633468 |
| PTMA | prothymosin, alpha | -0.0608881 |
| HMGB2 | high mobility group box 2 | -0.0587145 |
| MKI67 | marker of proliferation Ki-67 | -0.058321 |
| CENPE | centromere protein E, 312kDa | -0.0569106 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0524795 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0520259 |
| RPS8 | ribosomal protein S8 | -0.0510725 |
| ACTG1 | actin gamma 1 | -0.0509204 |
| PHIP | pleckstrin homology domain interacting protein | -0.0505761 |
| RPLP1 | ribosomal protein, large, P1 | -0.0497995 |
| PCM1 | pericentriolar material 1 | -0.049626 |
| RPL7 | ribosomal protein L7 | -0.0495693 |
| RBM25 | RNA binding motif protein 25 | -0.0490025 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0440779 |
| TAOK1 | TAO kinase 1 | -0.0432832 |
| RPS23 | ribosomal protein S23 | -0.043262 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -0.0430626 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0416443 |
| IER3 | immediate early response 3 | -0.0416085 |
| RPS19 | ribosomal protein S19 | -0.0409622 |
| RPL34 | ribosomal protein L34 | -0.0399112 |
| RPLP2 | ribosomal protein, large, P2 | -0.0398003 |
| RPS3 | ribosomal protein S3 | -0.0396303 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0394872 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0391698 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0390547 |
| RPL11 | ribosomal protein L11 | -0.0386027 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0384411 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377124 |
| RACK1 | receptor for activated C kinase 1 | -0.0376728 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0375474 |
| BPTF | bromodomain PHD finger transcription factor | -0.0367876 |
| SEPTIN11 | septin 11 | -0.0364577 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0361894 |
| ANKRD17 | ankyrin repeat domain 17 | -0.035926 |
| RPL36 | ribosomal protein L36 | -0.0354635 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0350101 |
| RPS12 | ribosomal protein S12 | -0.0344395 |
| RPL7A | ribosomal protein L7a | -0.0342427 |
| PAPOLA | poly(A) polymerase alpha | -0.0340869 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0337695 |
| SEPTIN7 | septin 7 | -0.0336673 |
| RPLP0 | ribosomal protein, large, P0 | -0.0336406 |
| VCL | vinculin | -0.0336303 |
| SMAP1 | small ArfGAP 1 | -0.0335285 |
| FTL | ferritin, light polypeptide | -0.0335233 |
| BCOR | BCL6 corepressor | -0.0332052 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0331771 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.032794 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0322598 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0321482 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0319926 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0316108 |
| S100A9 | S100 calcium binding protein A9 | -0.0315306 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0312341 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.031207 |
| RPL19 | ribosomal protein L19 | -0.0311535 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0310409 |
| MAP1B | microtubule-associated protein 1B | -0.0302933 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0294703 |
| PCDH7 | protocadherin 7 | -0.0290881 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0289877 |
| RPL37 | ribosomal protein L37 | -0.0289742 |
| SMC3 | structural maintenance of chromosomes 3 | -0.028938 |
| CCNI | cyclin I | -0.0287883 |
| CLTC | clathrin, heavy chain (Hc) | -0.0287844 |
| RPS15 | ribosomal protein S15 | -0.0287315 |
| USP34 | ubiquitin specific peptidase 34 | -0.0285274 |
| CANX | calnexin | -0.028255 |
| RPL8 | ribosomal protein L8 | -0.0281369 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0281097 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0279614 |
| RPL28 | ribosomal protein L28 | -0.0278871 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0276364 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0276264 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0275458 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0275063 |
| DCP2 | decapping mRNA 2 | -0.0273451 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0272607 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0272069 |
| CEP192 | centrosomal protein 192kDa | -0.0270742 |
| RPS24 | ribosomal protein S24 | -0.0270493 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0269531 |
| OGA | O-GlcNAcase | -0.0268475 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0267428 |
| RPL13A | ribosomal protein L13a | -0.0265354 |
| TMSB10 | thymosin beta 10 | -0.0264671 |
