| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.338987 |
| COL3A1 | collagen, type III, alpha 1 | 0.078075 |
| FAM13A | family with sequence similarity 13, member A | 0.0779154 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0750222 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0708931 |
| MSI2 | musashi RNA-binding protein 2 | 0.0666768 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0658245 |
| SEPTIN9 | septin 9 | 0.064881 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0612757 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0603872 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0600297 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0533149 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0532796 |
| PKM | pyruvate kinase, muscle | 0.0517385 |
| PCBP2 | poly(rC) binding protein 2 | 0.0509904 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0499183 |
| MEF2A | myocyte enhancer factor 2A | 0.0480177 |
| CADM1 | cell adhesion molecule 1 | 0.0473979 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0468751 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0435621 |
| WAC | WW domain containing adaptor with coiled-coil | 0.042465 |
| VIM | vimentin | 0.0405495 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0402658 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.040157 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0392752 |
| HELZ | helicase with zinc finger | 0.0392738 |
| NDRG1 | N-myc downstream regulated 1 | 0.038675 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0371298 |
| SETD5 | SET domain containing 5 | 0.0370717 |
| SQSTM1 | sequestosome 1 | 0.0364996 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0359365 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0359253 |
| RPL3 | ribosomal protein L3 | 0.0356507 |
| SMAD3 | SMAD family member 3 | 0.0352421 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0345371 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0343784 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.034097 |
| XPO1 | exportin 1 | 0.0329624 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0324441 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0315039 |
| WDR45B | WD repeat domain 45B | 0.0308396 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0307131 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0302323 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0300345 |
| ENO1 | enolase 1, (alpha) | 0.0296926 |
| ANXA2 | annexin A2 | 0.0290115 |
| RNF145 | ring finger protein 145 | 0.0288096 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0287889 |
| FAM168A | family with sequence similarity 168, member A | 0.0287881 |
| TOP1 | topoisomerase (DNA) I | 0.028706 |
| COL4A5 | collagen, type IV, alpha 5 | 0.028104 |
| GPHN | gephyrin | 0.0276565 |
| VCAN | versican | 0.0275073 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0268845 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0267822 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0264602 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0263896 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0261245 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260084 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0259915 |
| ZFP36 | ZFP36 ring finger protein | 0.0259482 |
| FDXR | ferredoxin reductase | 0.0252745 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.025056 |
| TMEM123 | transmembrane protein 123 | 0.0250046 |
| PTMA | prothymosin, alpha | 0.0248871 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0248373 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245859 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.024517 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0244834 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0242834 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0242151 |
| ARMC9 | armadillo repeat containing 9 | 0.0241196 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0240438 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0238921 |
| RPL35A | ribosomal protein L35a | 0.0238918 |
| APP | amyloid beta (A4) precursor protein | 0.0238525 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.023807 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0236611 |
| NUP58 | nucleoporin 58 | 0.0232433 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0232131 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.023009 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0229304 |
| EXT1 | exostosin glycosyltransferase 1 | 0.02276 |
| ZNF148 | zinc finger protein 148 | 0.0227344 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0226822 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0225423 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0225246 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0225132 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0224653 |
| FCHO2 | FCH domain only 2 | 0.02228 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0221607 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0219945 |
| POTEF | POTE ankyrin domain family, member F | 0.0218171 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0216974 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0216444 |
| ADAR | adenosine deaminase, RNA-specific | 0.0216153 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0215336 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0215295 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0213024 |
| TRIB2 | tribbles pseudokinase 2 | 0.0212974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.198454 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120524 |
| TLE4 | transducin-like enhancer of split 4 | -0.0959641 |
| SYT1 | synaptotagmin I | -0.0654177 |
| NRG1 | neuregulin 1 | -0.0623385 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0587066 |
| BPTF | bromodomain PHD finger transcription factor | -0.0568363 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0566518 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0537868 |
| VMP1 | vacuole membrane protein 1 | -0.0461627 |
| NCAM2 | neural cell adhesion molecule 2 | -0.04465 |
| MBTD1 | mbt domain containing 1 | -0.0442559 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0437703 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0437323 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0409363 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0405375 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0396432 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0394522 |
| JMJD1C | jumonji domain containing 1C | -0.036518 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0362293 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0361088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0344515 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.033344 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0331913 |
| SMYD3 | SET and MYND domain containing 3 | -0.032959 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0326024 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0325641 |
| GPATCH8 | G patch domain containing 8 | -0.0323638 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0318454 |
| DPH6 | diphthamine biosynthesis 6 | -0.0312551 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.030859 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0304448 |
| FMN1 | formin 1 | -0.0303288 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0299577 |
| CLTC | clathrin, heavy chain (Hc) | -0.0299461 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0298673 |
| PRKCA | protein kinase C, alpha | -0.0297198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0287806 |
| ZNF207 | zinc finger protein 207 | -0.0283936 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0281838 |
| RPS2 | ribosomal protein S2 | -0.0281614 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0280918 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0279603 |
| ANO6 | anoctamin 6 | -0.0279531 |
| EP300 | E1A binding protein p300 | -0.0279322 |
| SLC38A2 | solute carrier family 38, member 2 | -0.027889 |
| HMBOX1 | homeobox containing 1 | -0.0276976 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0274784 |
| KLHL13 | kelch-like family member 13 | -0.0274122 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0274 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0272922 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0270034 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0268555 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0266936 |
| ANGPT1 | angiopoietin 1 | -0.0264766 |
| FAM193A | family with sequence similarity 193, member A | -0.0262832 |
| TMF1 | TATA element modulatory factor 1 | -0.0261861 |
| MEIS2 | Meis homeobox 2 | -0.0258054 |
| ZNF804A | zinc finger protein 804A | -0.0255508 |
| CEP170 | centrosomal protein 170kDa | -0.0254137 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0250892 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0247651 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0245524 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0243047 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0240648 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0238899 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0238889 |
| LPIN1 | lipin 1 | -0.0234638 |
| EXOC4 | exocyst complex component 4 | -0.0234026 |
| THBS1 | thrombospondin 1 | -0.0233018 |
| ACTG1 | actin gamma 1 | -0.023288 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0232579 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0232471 |
| HMGA2 | high mobility group AT-hook 2 | -0.0232367 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0228974 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0227294 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0226923 |
| CEP95 | centrosomal protein 95kDa | -0.0225984 |
| DUSP10 | dual specificity phosphatase 10 | -0.0225863 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224615 |
| MAP1B | microtubule-associated protein 1B | -0.0224063 |
| RPL38 | ribosomal protein L38 | -0.0223746 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0221953 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0219088 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.0218376 |
| RPS6 | ribosomal protein S6 | -0.0217585 |
| GOLGB1 | golgin B1 | -0.0216743 |
| NME7 | NME/NM23 family member 7 | -0.0214756 |
| ATRNL1 | attractin-like 1 | -0.0214635 |
| PCTP | phosphatidylcholine transfer protein | -0.0214292 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0213849 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0213208 |
| RPL7 | ribosomal protein L7 | -0.0212435 |
| PARD3 | par-3 family cell polarity regulator | -0.0210974 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0208295 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0208274 |
| MYO9A | myosin IXA | -0.0207797 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0207661 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0207112 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0206928 |
