| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.183098 |
| FLNB | filamin B, beta | 0.170719 |
| SLC35F3 | solute carrier family 35, member F3 | 0.124078 |
| PLEC | plectin | 0.121017 |
| MTSS1 | metastasis suppressor 1 | 0.118815 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.117289 |
| GRB10 | growth factor receptor-bound protein 10 | 0.117096 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.111334 |
| LMO7 | LIM domain 7 | 0.0928134 |
| MEF2A | myocyte enhancer factor 2A | 0.0887959 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0784028 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0783251 |
| PODXL | podocalyxin-like | 0.0780811 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0754094 |
| KRT6A | keratin 6A, type II | 0.072142 |
| SULF1 | sulfatase 1 | 0.0714909 |
| MEGF6 | multiple EGF-like-domains 6 | 0.069425 |
| LAMA5 | laminin, alpha 5 | 0.069411 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0658891 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0639455 |
| RAI14 | retinoic acid induced 14 | 0.0637093 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.062992 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0625963 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0623872 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0618618 |
| PCBP2 | poly(rC) binding protein 2 | 0.0611866 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0603804 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0585673 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.056494 |
| EZR | ezrin | 0.0556659 |
| NCOR2 | nuclear receptor corepressor 2 | 0.05507 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0543012 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0523521 |
| KIAA1671 | KIAA1671 | 0.0522514 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0519889 |
| ENO1 | enolase 1, (alpha) | 0.0498003 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0480824 |
| MYO10 | myosin X | 0.0480154 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0477117 |
| NRCAM | neuronal cell adhesion molecule | 0.0464714 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0464002 |
| LAMC2 | laminin, gamma 2 | 0.0461575 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0461225 |
| FOXO1 | forkhead box O1 | 0.0459811 |
| DHFR | dihydrofolate reductase | 0.0450019 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0448121 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0447297 |
| PGK1 | phosphoglycerate kinase 1 | 0.0446308 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0426225 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0416575 |
| ITGB4 | integrin, beta 4 | 0.0413948 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0413437 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0412705 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0410234 |
| RPL3 | ribosomal protein L3 | 0.0405459 |
| MCL1 | myeloid cell leukemia 1 | 0.040189 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0396644 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0391821 |
| PLEKHG5 | pleckstrin homology domain containing, family G (with RhoGef domain) member 5 | 0.0389205 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0387204 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0381044 |
| SULF2 | sulfatase 2 | 0.0380619 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0378377 |
| AHNAK | AHNAK nucleoprotein | 0.0374096 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.037246 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0369817 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0369657 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0365238 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0364844 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0364157 |
| AMOTL1 | angiomotin like 1 | 0.0362832 |
| APP | amyloid beta (A4) precursor protein | 0.0357795 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0353325 |
| NAV2 | neuron navigator 2 | 0.0344145 |
| TPM4 | tropomyosin 4 | 0.0320663 |
| KRT5 | keratin 5, type II | 0.0320548 |
| WNT7B | wingless-type MMTV integration site family, member 7B | 0.0319068 |
| TNS3 | tensin 3 | 0.0315765 |
| RPS18 | ribosomal protein S18 | 0.031259 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0312545 |
| KRT17 | keratin 17, type I | 0.030863 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0308508 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0305863 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0304075 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0302994 |
| SYNJ2 | synaptojanin 2 | 0.0299436 |
| POTEF | POTE ankyrin domain family, member F | 0.029734 |
| MXRA5 | matrix-remodelling associated 5 | 0.0293686 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0292184 |
| ECE1 | endothelin converting enzyme 1 | 0.029207 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.028692 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0284575 |
| KRT14 | keratin 14, type I | 0.0284561 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.028411 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283928 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0283061 |
| ANXA11 | annexin A11 | 0.0281564 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0280101 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0277407 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0269233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221309 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0898397 |
| RPS6 | ribosomal protein S6 | -0.0817843 |
| RPS21 | ribosomal protein S21 | -0.0810866 |
| CLU | clusterin | -0.0778402 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0778334 |
| NDRG1 | N-myc downstream regulated 1 | -0.0773586 |
| TMSB4X | thymosin beta 4, X-linked | -0.0614605 |
| RPLP2 | ribosomal protein, large, P2 | -0.0563019 |
| RPS2 | ribosomal protein S2 | -0.051599 |
| IGF2 | insulin-like growth factor 2 | -0.0514557 |
| RPS8 | ribosomal protein S8 | -0.0501097 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0500609 |
| OSMR | oncostatin M receptor | -0.0467185 |
| CANX | calnexin | -0.0461827 |
| ASPH | aspartate beta-hydroxylase | -0.0461286 |
| MT2A | metallothionein 2A | -0.0453906 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0438664 |
| FN1 | fibronectin 1 | -0.0432408 |
| RBM39 | RNA binding motif protein 39 | -0.0428988 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0424936 |
| RPL8 | ribosomal protein L8 | -0.0420912 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0401477 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0397476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0394183 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0391069 |
| MYO9A | myosin IXA | -0.0390136 |
| RIN2 | Ras and Rab interactor 2 | -0.0384273 |
| ANLN | anillin, actin binding protein | -0.0383092 |
| GOLGA4 | golgin A4 | -0.0376843 |
| ARRDC3 | arrestin domain containing 3 | -0.0373386 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0373312 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0371214 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0366402 |
| RPS24 | ribosomal protein S24 | -0.0365312 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0355323 |
| RPL7 | ribosomal protein L7 | -0.0354567 |
| RPS13 | ribosomal protein S13 | -0.0340668 |
| RPL11 | ribosomal protein L11 | -0.0338067 |
| RPL7A | ribosomal protein L7a | -0.0331617 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0329562 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0329382 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0326518 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0313983 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0311879 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0306445 |
| JMJD1C | jumonji domain containing 1C | -0.0305005 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0304417 |
| RPS25 | ribosomal protein S25 | -0.0301246 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0299504 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0297251 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0293511 |
| GOLGB1 | golgin B1 | -0.0288907 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0287846 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0282717 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0278971 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0278205 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0276532 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0273706 |
| IL6ST | interleukin 6 signal transducer | -0.0273552 |
| S100A9 | S100 calcium binding protein A9 | -0.0272664 |
| CUL4B | cullin 4B | -0.0268302 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0268122 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0267142 |
| DSTN | destrin (actin depolymerizing factor) | -0.0266892 |
| HM13 | histocompatibility (minor) 13 | -0.0266614 |
| S100A10 | S100 calcium binding protein A10 | -0.02661 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0265967 |
| SERINC3 | serine incorporator 3 | -0.0265083 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0264457 |
| PRELID2 | PRELI domain containing 2 | -0.0264358 |
| MTPN | myotrophin | -0.0263985 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0261683 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0260886 |
| RPL37A | ribosomal protein L37a | -0.025898 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0258709 |
| VMP1 | vacuole membrane protein 1 | -0.0258166 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0257106 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0254594 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0253978 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0253454 |
| RPS27A | ribosomal protein S27a | -0.0252923 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0251562 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0248411 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0244908 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0244869 |
| RPL27A | ribosomal protein L27a | -0.0242045 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0240338 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239459 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0234244 |
| RB1 | retinoblastoma 1 | -0.0234195 |
| HIP1 | huntingtin interacting protein 1 | -0.0232338 |
| CLTC | clathrin, heavy chain (Hc) | -0.0232287 |
| RPL26 | ribosomal protein L26 | -0.0232225 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0230075 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0228435 |
| RPLP0 | ribosomal protein, large, P0 | -0.0227173 |
| TPX2 | TPX2, microtubule-associated | -0.0227073 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0226785 |
| METTL15 | methyltransferase like 15 | -0.0226404 |
