| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.163101 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11694 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.116793 |
| HYOU1 | hypoxia up-regulated 1 | 0.102665 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0875403 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0732837 |
| PCBP2 | poly(rC) binding protein 2 | 0.0722914 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0713061 |
| POTEF | POTE ankyrin domain family, member F | 0.0696613 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0695681 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0692575 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0661271 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0658509 |
| MYOF | myoferlin | 0.0653788 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0625196 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0615081 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0602651 |
| GOLGA4 | golgin A4 | 0.0592267 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0585398 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0567767 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0559579 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0547695 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0538912 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0536968 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0521935 |
| DSPP | dentin sialophosphoprotein | 0.0511465 |
| KLHL29 | kelch-like family member 29 | 0.0504678 |
| CALR | calreticulin | 0.0495924 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0489867 |
| EZR | ezrin | 0.0489227 |
| SETD5 | SET domain containing 5 | 0.0488957 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0488676 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.047722 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0469015 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0462377 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0455645 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0448888 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0444884 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0438416 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0420746 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0411609 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0409505 |
| TES | testin LIM domain protein | 0.0397301 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0387215 |
| PLEC | plectin | 0.0375002 |
| B2M | beta-2-microglobulin | 0.037311 |
| S100A6 | S100 calcium binding protein A6 | 0.0370918 |
| ANXA11 | annexin A11 | 0.0366377 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0364359 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.035965 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.035933 |
| XPO1 | exportin 1 | 0.0359234 |
| ATP11A | ATPase, class VI, type 11A | 0.035746 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0356853 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0355914 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0352553 |
| DSTN | destrin (actin depolymerizing factor) | 0.0350836 |
| CMIP | c-Maf inducing protein | 0.0349195 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0347682 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0347633 |
| TPM3 | tropomyosin 3 | 0.0346966 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0345754 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0345362 |
| AREG | amphiregulin | 0.0343086 |
| SEPTIN9 | septin 9 | 0.0342253 |
| KRT18 | keratin 18, type I | 0.0341663 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0335747 |
| OGA | O-GlcNAcase | 0.0334198 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0333998 |
| ITGB4 | integrin, beta 4 | 0.0332596 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0330732 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0329548 |
| CTBP2 | C-terminal binding protein 2 | 0.0329363 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0328722 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0324091 |
| COG5 | component of oligomeric golgi complex 5 | 0.0321696 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0321368 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0319664 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0318642 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0317404 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.03154 |
| SMAD3 | SMAD family member 3 | 0.0313179 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0306873 |
| MB21D2 | Mab-21 domain containing 2 | 0.0305504 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0305344 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0305313 |
| SPAG9 | sperm associated antigen 9 | 0.0305229 |
| MORF4L2 | mortality factor 4 like 2 | 0.0304063 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0301425 |
| RPS18 | ribosomal protein S18 | 0.0300399 |
| STK24 | serine/threonine kinase 24 | 0.0296161 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0294063 |
| ARCN1 | archain 1 | 0.0293181 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0289059 |
| ANXA2 | annexin A2 | 0.0278948 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0278905 |
| RBM39 | RNA binding motif protein 39 | 0.0276791 |
| GAN | gigaxonin | 0.0276706 |
| AFDN | afadin, adherens junction formation factor | 0.0272902 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0272662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.123788 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0768618 |
| TMSB10 | thymosin beta 10 | -0.0462587 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0397428 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0378442 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0371511 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0329922 |
| POF1B | premature ovarian failure, 1B | -0.0314796 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0300827 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0299225 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.029229 |
| PHF14 | PHD finger protein 14 | -0.0288505 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0278696 |
| PLSCR1 | phospholipid scramblase 1 | -0.0276759 |
| RUNX1 | runt-related transcription factor 1 | -0.0275411 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.027132 |
| ASPH | aspartate beta-hydroxylase | -0.0267101 |
| PCDH7 | protocadherin 7 | -0.0257362 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0256756 |
| RNF213 | ring finger protein 213 | -0.0246136 |
| NDRG1 | N-myc downstream regulated 1 | -0.0237253 |
| EFNA5 | ephrin-A5 | -0.0229836 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0226963 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0224806 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0220643 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0220451 |
| AUTS2 | autism susceptibility candidate 2 | -0.0219309 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0218668 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0216965 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0216886 |
| EXOC4 | exocyst complex component 4 | -0.0216684 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0208864 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0203672 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0203379 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.020195 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0201747 |
| ETV6 | ets variant 6 | -0.0198595 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0197529 |
| PGK1 | phosphoglycerate kinase 1 | -0.0197083 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0195597 |
| CDK6 | cyclin-dependent kinase 6 | -0.0195067 |
| MX1 | MX dynamin-like GTPase 1 | -0.0195018 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0193763 |
| INTS6 | integrator complex subunit 6 | -0.0193322 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0192433 |
| LMO7 | LIM domain 7 | -0.0191926 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0189239 |
| MECOM | MDS1 and EVI1 complex locus | -0.0188956 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0188308 |
| MCU | mitochondrial calcium uniporter | -0.0186781 |
| EHBP1 | EH domain binding protein 1 | -0.0183194 |
| TFRC | transferrin receptor | -0.0183032 |
| TMC5 | transmembrane channel-like 5 | -0.0182568 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0181006 |
| PKP4 | plakophilin 4 | -0.0178332 |
| CCND1 | cyclin D1 | -0.0178229 |
| DIAPH2 | diaphanous-related formin 2 | -0.0174001 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.01737 |
| DGKH | diacylglycerol kinase, eta | -0.0172948 |
| ATM | ATM serine/threonine kinase | -0.0170942 |
| TCF12 | transcription factor 12 | -0.01705 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0168841 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0166568 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0164841 |
| RIGI | RNA sensor RIG-I | -0.0163314 |
| ONECUT3 | one cut homeobox 3 | -0.0161703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.015991 |
| THADA | thyroid adenoma associated | -0.0158544 |
| RRBP1 | ribosome binding protein 1 | -0.0157471 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0155378 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0153329 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0152536 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0151701 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0150793 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0150729 |
| MUC13 | mucin 13, cell surface associated | -0.0149336 |
| MTAP | methylthioadenosine phosphorylase | -0.0148196 |
| RESF1 | retroelement silencing factor 1 | -0.0144898 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0144763 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0144679 |
| SCFD2 | sec1 family domain containing 2 | -0.0144197 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0144194 |
| SP100 | SP100 nuclear antigen | -0.0143826 |
| AHR | aryl hydrocarbon receptor | -0.0143757 |
| PRKCA | protein kinase C, alpha | -0.0143675 |
| AEBP2 | AE binding protein 2 | -0.0143633 |
| PIWIL4 | piwi-like RNA-mediated gene silencing 4 | -0.0143509 |
| TMSB4X | thymosin beta 4, X-linked | -0.0143219 |
| EPCAM | epithelial cell adhesion molecule | -0.0140834 |
| PRELID2 | PRELI domain containing 2 | -0.0139673 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0138488 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | -0.0137508 |
| ACTG1 | actin gamma 1 | -0.0136805 |
| EXPH5 | exophilin 5 | -0.013436 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0134217 |
| HMGB1 | high mobility group box 1 | -0.0134183 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0132319 |
| SH3D19 | SH3 domain containing 19 | -0.0132291 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0132088 |
| CCDC146 | coiled-coil domain containing 146 | -0.0131678 |
