| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS18 | ribosomal protein S18 | 0.0954581 |
| PCBP2 | poly(rC) binding protein 2 | 0.0788215 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0741105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0687843 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0682187 |
| LSAMP | limbic system-associated membrane protein | 0.0634597 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.057851 |
| CD109 | CD109 molecule | 0.0571953 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0510164 |
| PGK1 | phosphoglycerate kinase 1 | 0.0508365 |
| APP | amyloid beta (A4) precursor protein | 0.050369 |
| ATP13A3 | ATPase type 13A3 | 0.0497105 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0496238 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.049045 |
| RPL3 | ribosomal protein L3 | 0.0487773 |
| SMAD3 | SMAD family member 3 | 0.047051 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0464733 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.046469 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0446628 |
| NUP58 | nucleoporin 58 | 0.044144 |
| FN1 | fibronectin 1 | 0.0392977 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0387995 |
| RPS3 | ribosomal protein S3 | 0.0366802 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0352952 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0351864 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.03391 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0334322 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0312301 |
| RPS12 | ribosomal protein S12 | 0.0306971 |
| PLEC | plectin | 0.0288116 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0284809 |
| FRMD6 | FERM domain containing 6 | 0.027816 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026664 |
| HMGA1 | high mobility group AT-hook 1 | 0.0260114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0259753 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0256452 |
| TPM3 | tropomyosin 3 | 0.0255766 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0252318 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0249032 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0248947 |
| RPL12 | ribosomal protein L12 | 0.0247475 |
| RPS2 | ribosomal protein S2 | 0.024545 |
| FLNA | filamin A, alpha | 0.0244462 |
| MYO10 | myosin X | 0.0244367 |
| RPS7 | ribosomal protein S7 | 0.0241933 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0241847 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0236583 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0232285 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0229754 |
| PRRC2C | proline-rich coiled-coil 2C | 0.022599 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0224528 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0224419 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0223817 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.022371 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0219227 |
| VCL | vinculin | 0.0217634 |
| ACTN1 | actinin, alpha 1 | 0.0216947 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0215169 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0214554 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0210898 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0207985 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0206952 |
| AHNAK | AHNAK nucleoprotein | 0.0194561 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0192323 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0191834 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0191202 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0189918 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0186819 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0186454 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0183917 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0182647 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0181171 |
| CD59 | CD59 molecule, complement regulatory protein | 0.017803 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0177767 |
| LOXL2 | lysyl oxidase-like 2 | 0.0175728 |
| RYBP | RING1 and YY1 binding protein | 0.0175341 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0173058 |
| ADM | adrenomedullin | 0.0173035 |
| SERINC1 | serine incorporator 1 | 0.0170038 |
| RBM4 | RNA binding motif protein 4 | 0.0168296 |
| BAG6 | BCL2-associated athanogene 6 | 0.0168082 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0167406 |
| MYO6 | myosin VI | 0.0165706 |
| CDK17 | cyclin-dependent kinase 17 | 0.0163598 |
| DHFR | dihydrofolate reductase | 0.0163325 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0161933 |
| USP22 | ubiquitin specific peptidase 22 | 0.0159814 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0159168 |
| CALR | calreticulin | 0.015752 |
| RPS15A | ribosomal protein S15a | 0.0157515 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0157316 |
| NRP2 | neuropilin 2 | 0.0152417 |
| FAT1 | FAT atypical cadherin 1 | 0.0152397 |
| RNF145 | ring finger protein 145 | 0.0151222 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0151165 |
| FMNL2 | formin-like 2 | 0.0148725 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0148263 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0148219 |
| RBM39 | RNA binding motif protein 39 | 0.0147269 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0147088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.434835 |
| VIM | vimentin | -0.201524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.12675 |
| DTNA | dystrobrevin, alpha | -0.0896448 |
| EFNA5 | ephrin-A5 | -0.0845197 |
| ACTG1 | actin gamma 1 | -0.0733159 |
| RPS6 | ribosomal protein S6 | -0.0690076 |
| MMP12 | matrix metallopeptidase 12 | -0.0668152 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0630232 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0546371 |
| JMJD1C | jumonji domain containing 1C | -0.0544707 |
| DST | dystonin | -0.0503852 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0483755 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.047175 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0425903 |
| BPTF | bromodomain PHD finger transcription factor | -0.0408242 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.040434 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0401739 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0391267 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0373792 |
| USP34 | ubiquitin specific peptidase 34 | -0.0373653 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0372258 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0369228 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0355295 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0353892 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0350867 |
| EGR1 | early growth response 1 | -0.0346991 |
| ERBIN | erbb2 interacting protein | -0.0346414 |
| FTL | ferritin, light polypeptide | -0.0341858 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0341481 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0340815 |
| CALD1 | caldesmon 1 | -0.0333304 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0333053 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0331 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0312532 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0310808 |
| RPL35A | ribosomal protein L35a | -0.0310294 |
| GPC6 | glypican 6 | -0.030799 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0297593 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0297101 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0287896 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0284614 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282089 |
| SSH2 | slingshot protein phosphatase 2 | -0.0281212 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0281165 |
| NABP1 | nucleic acid binding protein 1 | -0.0281061 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0277633 |
| NF1 | neurofibromin 1 | -0.0271953 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0271748 |
| RFX7 | regulatory factor X, 7 | -0.0271548 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0271499 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0268909 |
| PFN1 | profilin 1 | -0.0268234 |
| HMGA2 | high mobility group AT-hook 2 | -0.0263841 |
| SBF2 | SET binding factor 2 | -0.026173 |
| RPL8 | ribosomal protein L8 | -0.0261441 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0257575 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0255367 |
| MSR1 | macrophage scavenger receptor 1 | -0.0255088 |
| NBEAL1 | neurobeachin-like 1 | -0.0252084 |
| ZNF638 | zinc finger protein 638 | -0.0251685 |
| PTCHD4 | patched domain containing 4 | -0.0251116 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0250135 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0249523 |
| RPS25 | ribosomal protein S25 | -0.0247917 |
| PARD3 | par-3 family cell polarity regulator | -0.0245441 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0245262 |
| FBXO11 | F-box protein 11 | -0.0243854 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0242001 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0240952 |
| PTK2 | protein tyrosine kinase 2 | -0.0240195 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0238808 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0238695 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0238245 |
| RPS24 | ribosomal protein S24 | -0.0237496 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0235359 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0234403 |
| RTN4 | reticulon 4 | -0.0233725 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0230982 |
| TMSB10 | thymosin beta 10 | -0.0229536 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0227294 |
| RAB10 | RAB10, member RAS oncogene family | -0.0225893 |
| RPLP2 | ribosomal protein, large, P2 | -0.0225447 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0224727 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0224085 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.022274 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0222015 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0221348 |
| GPHN | gephyrin | -0.0221079 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0219471 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0216041 |
| ZNF207 | zinc finger protein 207 | -0.0215709 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.021534 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0214301 |
| TMEM87A | transmembrane protein 87A | -0.0214078 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0213948 |
| INTS6 | integrator complex subunit 6 | -0.0211934 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211187 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0210458 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0206772 |
