| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.162053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.140692 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.13153 |
| EREG | epiregulin | 0.105562 |
| TXNIP | thioredoxin interacting protein | 0.105334 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.078099 |
| RNF145 | ring finger protein 145 | 0.0752961 |
| PCBP2 | poly(rC) binding protein 2 | 0.0724019 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0646506 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0644268 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0611045 |
| MED13L | mediator complex subunit 13-like | 0.0601556 |
| CALR | calreticulin | 0.0595682 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0582614 |
| RREB1 | ras responsive element binding protein 1 | 0.057737 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0576261 |
| PIGR | polymeric immunoglobulin receptor | 0.057062 |
| RPS18 | ribosomal protein S18 | 0.0568105 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0563274 |
| RPL3 | ribosomal protein L3 | 0.0542105 |
| KRT8 | keratin 8, type II | 0.0527894 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0512716 |
| TPM4 | tropomyosin 4 | 0.0499192 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0493395 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0488837 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0482826 |
| KRT18 | keratin 18, type I | 0.047302 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0468925 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.045848 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0451289 |
| EZR | ezrin | 0.0449531 |
| FNBP1L | formin binding protein 1-like | 0.0443523 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0428061 |
| PTMA | prothymosin, alpha | 0.0418059 |
| CTBP2 | C-terminal binding protein 2 | 0.0402255 |
| TFG | TRK-fused gene | 0.0397561 |
| VEGFA | vascular endothelial growth factor A | 0.0386426 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0375565 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0374685 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0369395 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0368566 |
| ABHD17C | abhydrolase domain containing 17C | 0.0368164 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0367571 |
| EHF | ets homologous factor | 0.0366884 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0363397 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0358366 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0357105 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.034522 |
| CCNL1 | cyclin L1 | 0.0345007 |
| TNS4 | tensin 4 | 0.0343297 |
| ANXA11 | annexin A11 | 0.0340676 |
| TPM3 | tropomyosin 3 | 0.0340166 |
| XPO1 | exportin 1 | 0.0338793 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338619 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0336354 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0336208 |
| MYO5B | myosin VB | 0.0333735 |
| ITGB4 | integrin, beta 4 | 0.0322989 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0322126 |
| SETD5 | SET domain containing 5 | 0.0321617 |
| TJP2 | tight junction protein 2 | 0.031641 |
| RPS12 | ribosomal protein S12 | 0.030873 |
| ENO1 | enolase 1, (alpha) | 0.0308255 |
| CUL3 | cullin 3 | 0.0307358 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0305527 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0302753 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0301774 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0300458 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0299048 |
| RBM39 | RNA binding motif protein 39 | 0.0298261 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0292391 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0291284 |
| H2AC6 | H2A clustered histone 6 | 0.0290839 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0290085 |
| FLNB | filamin B, beta | 0.0286109 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0286013 |
| DNM2 | dynamin 2 | 0.0285358 |
| HYOU1 | hypoxia up-regulated 1 | 0.0284282 |
| FAT1 | FAT atypical cadherin 1 | 0.0282634 |
| FOSL1 | FOS-like antigen 1 | 0.0282416 |
| ABHD2 | abhydrolase domain containing 2 | 0.0280075 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0279946 |
| PLEC | plectin | 0.0278307 |
| AFDN | afadin, adherens junction formation factor | 0.0277723 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0277535 |
| B2M | beta-2-microglobulin | 0.0275807 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0275571 |
| ZNF148 | zinc finger protein 148 | 0.0275249 |
| APP | amyloid beta (A4) precursor protein | 0.0275063 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0272322 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0270557 |
| COPA | coatomer protein complex, subunit alpha | 0.0269297 |
| GAN | gigaxonin | 0.0268144 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0267115 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.026587 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0265156 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0264033 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0263305 |
| S100A6 | S100 calcium binding protein A6 | 0.0262974 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0262535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2432 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.126622 |
| NPSR1 | neuropeptide S receptor 1 | -0.0834153 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0663666 |
| TMSB10 | thymosin beta 10 | -0.0641034 |
| MYO1E | myosin IE | -0.0625594 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0601528 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0561794 |
| CADPS | Ca++-dependent secretion activator | -0.055763 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0549533 |
| GPHN | gephyrin | -0.0534267 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0524077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0492437 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0491471 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0470473 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0444433 |
| POF1B | premature ovarian failure, 1B | -0.0407608 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0388683 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0387796 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0386205 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0379199 |
| CD44 | CD44 molecule (Indian blood group) | -0.037657 |
| RPL35A | ribosomal protein L35a | -0.0368963 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0368753 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0346828 |
| MUC13 | mucin 13, cell surface associated | -0.0344835 |
| LOC112694756 | uncharaterized LOC112694756 | -0.033915 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.032703 |
| ACTG1 | actin gamma 1 | -0.0320813 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0319546 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0313692 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0303134 |
| RPS6 | ribosomal protein S6 | -0.0302761 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0302305 |
| ANXA1 | annexin A1 | -0.030172 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0299904 |
| RPL34 | ribosomal protein L34 | -0.0295164 |
| PRELID2 | PRELI domain containing 2 | -0.0290434 |
| ATXN1 | ataxin 1 | -0.0289701 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0287389 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282574 |
| EHBP1 | EH domain binding protein 1 | -0.0274835 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0274187 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0273894 |
| SBF2 | SET binding factor 2 | -0.0267621 |
| ARFGEF3 | ARFGEF family member 3 | -0.0266451 |
| SVIL | supervillin | -0.0265047 |
| SMYD3 | SET and MYND domain containing 3 | -0.0264419 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0263709 |
| VCL | vinculin | -0.026306 |
| GDF15 | growth differentiation factor 15 | -0.0259622 |
| LAMA4 | laminin, alpha 4 | -0.0257857 |
| H1-0 | H1.0 linker histone | -0.0251151 |
| MYO1D | myosin ID | -0.0244726 |
| RPS8 | ribosomal protein S8 | -0.024278 |
| RPL8 | ribosomal protein L8 | -0.0233286 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0232367 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0227132 |
| RPLP2 | ribosomal protein, large, P2 | -0.0224061 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0220548 |
| RPS19 | ribosomal protein S19 | -0.0220063 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0219046 |
| RNF217 | ring finger protein 217 | -0.0217654 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0217189 |
| EXPH5 | exophilin 5 | -0.0217188 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.02122 |
| FRMD5 | FERM domain containing 5 | -0.0211816 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0209018 |
| RPL32 | ribosomal protein L32 | -0.020889 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0207668 |
| RRBP1 | ribosome binding protein 1 | -0.0206966 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0205659 |
| RPS24 | ribosomal protein S24 | -0.0204884 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0201603 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0200707 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.019879 |
| RND3 | Rho family GTPase 3 | -0.0198657 |
| S100A10 | S100 calcium binding protein A10 | -0.0198302 |
| EMP1 | epithelial membrane protein 1 | -0.0196598 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0196559 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0196431 |
| TBCA | tubulin folding cofactor A | -0.0196234 |
| ARF1 | ADP-ribosylation factor 1 | -0.0196018 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0194922 |
| DENND1A | DENN/MADD domain containing 1A | -0.0194729 |
| AGR2 | anterior gradient 2 | -0.019291 |
| KIAA1217 | KIAA1217 | -0.0192623 |
| RPS20 | ribosomal protein S20 | -0.0192601 |
| STK17A | serine/threonine kinase 17a | -0.0192381 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0191684 |
| EPHB2 | EPH receptor B2 | -0.0190053 |
| AEBP2 | AE binding protein 2 | -0.0189568 |
| HMGB1 | high mobility group box 1 | -0.0187949 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0187252 |
| RIN2 | Ras and Rab interactor 2 | -0.0187244 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0186181 |
| CUX1 | cut-like homeobox 1 | -0.0185993 |
| PALLD | palladin, cytoskeletal associated protein | -0.0185967 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0184717 |
| NBEAL1 | neurobeachin-like 1 | -0.0184257 |
