| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.122319 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114691 |
| COL11A1 | collagen, type XI, alpha 1 | 0.103065 |
| THBS1 | thrombospondin 1 | 0.0972872 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0972214 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0911096 |
| PHIP | pleckstrin homology domain interacting protein | 0.0840404 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0826649 |
| GPC3 | glypican 3 | 0.0772362 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0762646 |
| COL5A2 | collagen, type V, alpha 2 | 0.0723761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.07007 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0691114 |
| COL3A1 | collagen, type III, alpha 1 | 0.0649723 |
| CALR | calreticulin | 0.0643654 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0636459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0630149 |
| APP | amyloid beta (A4) precursor protein | 0.0614328 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.061108 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0602967 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0600146 |
| PCBP2 | poly(rC) binding protein 2 | 0.0572243 |
| POTEF | POTE ankyrin domain family, member F | 0.0563761 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0544609 |
| RHEB | Ras homolog enriched in brain | 0.0442782 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0436862 |
| DMD | dystrophin | 0.0435664 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0434195 |
| PLPP1 | phospholipid phosphatase 1 | 0.0433464 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0431326 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0431186 |
| CALU | calumenin | 0.0429607 |
| WDR43 | WD repeat domain 43 | 0.0423504 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0422528 |
| STAG2 | stromal antigen 2 | 0.0421448 |
| USP3 | ubiquitin specific peptidase 3 | 0.0421191 |
| RAD21 | RAD21 homolog (S. pombe) | 0.041931 |
| ITGAV | integrin, alpha V | 0.0419264 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0418492 |
| SRP54 | signal recognition particle 54kDa | 0.041421 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0413834 |
| TMSB4X | thymosin beta 4, X-linked | 0.0409396 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.039452 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.038754 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0385422 |
| ANLN | anillin, actin binding protein | 0.0383034 |
| XPO1 | exportin 1 | 0.0380342 |
| ZNF292 | zinc finger protein 292 | 0.0379223 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0379125 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0372703 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0370024 |
| TPX2 | TPX2, microtubule-associated | 0.0367676 |
| OLA1 | Obg-like ATPase 1 | 0.0363664 |
| ECT2 | epithelial cell transforming 2 | 0.0361509 |
| MKI67 | marker of proliferation Ki-67 | 0.0357863 |
| FOXG1 | forkhead box G1 | 0.0354904 |
| RAI1 | retinoic acid induced 1 | 0.0354454 |
| ENAH | enabled homolog (Drosophila) | 0.0347149 |
| RASAL2 | RAS protein activator like 2 | 0.0345022 |
| NEK7 | NIMA-related kinase 7 | 0.0342117 |
| LYPLA1 | lysophospholipase I | 0.0339931 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0338348 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0331576 |
| ANXA5 | annexin A5 | 0.0329935 |
| MEMO1 | mediator of cell motility 1 | 0.0329768 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0327047 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0325038 |
| SRPK2 | SRSF protein kinase 2 | 0.0325035 |
| NCKAP1 | NCK-associated protein 1 | 0.0322693 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0319953 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0318837 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0318521 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0316205 |
| YBX1 | Y box binding protein 1 | 0.0315308 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0312757 |
| CANX | calnexin | 0.031198 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0311697 |
| CENPF | centromere protein F, 350/400kDa | 0.0308417 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0306461 |
| COL1A2 | collagen, type I, alpha 2 | 0.0305558 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.030259 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.030228 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0301645 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.030108 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0300627 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0299824 |
| PHF21A | PHD finger protein 21A | 0.0298484 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0298113 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.029747 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0297272 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0296826 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0293894 |
| DST | dystonin | 0.0293677 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0293102 |
| LDHA | lactate dehydrogenase A | 0.0292267 |
| CERT1 | ceramide transporter 1 | 0.029054 |
| PGK1 | phosphoglycerate kinase 1 | 0.0287899 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0287832 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0286714 |
| PCDH9 | protocadherin 9 | 0.0284202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0958747 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0529738 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0490169 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455329 |
| RPL23 | ribosomal protein L23 | -0.0449508 |
| RPS12 | ribosomal protein S12 | -0.0445275 |
| RPL37A | ribosomal protein L37a | -0.0432543 |
| CADM2 | cell adhesion molecule 2 | -0.0425135 |
| RPL26 | ribosomal protein L26 | -0.0384061 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0379742 |
| RPLP2 | ribosomal protein, large, P2 | -0.0374971 |
| RPL37 | ribosomal protein L37 | -0.0355712 |
| RPS19 | ribosomal protein S19 | -0.0353709 |
| RPL35A | ribosomal protein L35a | -0.034632 |
| RPL30 | ribosomal protein L30 | -0.0345725 |
| RPS6 | ribosomal protein S6 | -0.0338397 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.031787 |
| MT2A | metallothionein 2A | -0.030584 |
| RPS21 | ribosomal protein S21 | -0.0303479 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0300542 |
| RPS16 | ribosomal protein S16 | -0.0299391 |
| RPL5 | ribosomal protein L5 | -0.0298053 |
| RPS3 | ribosomal protein S3 | -0.0297008 |
| HMGB1 | high mobility group box 1 | -0.0285972 |
| PFN1 | profilin 1 | -0.0279987 |
| RPL28 | ribosomal protein L28 | -0.0277415 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0275729 |
| RPL11 | ribosomal protein L11 | -0.0274639 |
| RPS17 | ribosomal protein S17 | -0.0271754 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0260503 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0258152 |
| RPS4X | ribosomal protein S4, X-linked | -0.0252972 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0251724 |
| RPL36 | ribosomal protein L36 | -0.0244887 |
| NXN | nucleoredoxin | -0.0242157 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0238151 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0237161 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0235502 |
| RPS13 | ribosomal protein S13 | -0.0229814 |
| RPL12 | ribosomal protein L12 | -0.0228571 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0227481 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225884 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0222936 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0221681 |
| BPTF | bromodomain PHD finger transcription factor | -0.0220635 |
| RPS27 | ribosomal protein S27 | -0.0217241 |
| CUX1 | cut-like homeobox 1 | -0.0214858 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0214711 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0213586 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0212976 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0212463 |
| PDCD5 | programmed cell death 5 | -0.0211786 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0209982 |
| RPS8 | ribosomal protein S8 | -0.0208094 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0206277 |
| FTL | ferritin, light polypeptide | -0.0205962 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0205283 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0200706 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0199892 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.019736 |
| RPL13A | ribosomal protein L13a | -0.019679 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0195429 |
| RPL31 | ribosomal protein L31 | -0.0194252 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0192014 |
| RPS27A | ribosomal protein S27a | -0.0190506 |
| FRYL | FRY-like | -0.0189499 |
| TRIM2 | tripartite motif containing 2 | -0.0187118 |
| FOXO1 | forkhead box O1 | -0.0185931 |
| PTMA | prothymosin, alpha | -0.0183047 |
| ROMO1 | reactive oxygen species modulator 1 | -0.0182732 |
| RPL27A | ribosomal protein L27a | -0.0182495 |
| S100A9 | S100 calcium binding protein A9 | -0.018155 |
| CBX3 | chromobox homolog 3 | -0.0181085 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0180209 |
| RPS23 | ribosomal protein S23 | -0.0179862 |
| MYADM | myeloid-associated differentiation marker | -0.0179484 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0178753 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0178053 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0177725 |
| RPS10 | ribosomal protein S10 | -0.0177708 |
| RBM25 | RNA binding motif protein 25 | -0.0177181 |
| RPL18 | ribosomal protein L18 | -0.0177178 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0176166 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0172561 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -0.0172556 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0171472 |
| RPL34 | ribosomal protein L34 | -0.0170583 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | -0.0168916 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0167786 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.0166691 |
| ZNF638 | zinc finger protein 638 | -0.0166574 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0166506 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0165948 |
| S100A10 | S100 calcium binding protein A10 | -0.0165249 |
| TENM3 | teneurin transmembrane protein 3 | -0.0164741 |
| RBM20 | RNA binding motif protein 20 | -0.0164292 |
| MYO9A | myosin IXA | -0.0163059 |
| FN1 | fibronectin 1 | -0.0161911 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0159495 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0158226 |
