| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.280388 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.18304 |
| CADM1 | cell adhesion molecule 1 | 0.180465 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.17521 |
| FNDC3B | fibronectin type III domain containing 3B | 0.154678 |
| NAV2 | neuron navigator 2 | 0.150014 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.116561 |
| PDE10A | phosphodiesterase 10A | 0.115093 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0995845 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0990479 |
| PCBP2 | poly(rC) binding protein 2 | 0.0928549 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.091933 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0871197 |
| ADM | adrenomedullin | 0.0860673 |
| VEGFA | vascular endothelial growth factor A | 0.0840685 |
| NDRG1 | N-myc downstream regulated 1 | 0.0838377 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0827748 |
| MYOF | myoferlin | 0.0793035 |
| FMNL2 | formin-like 2 | 0.0756291 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0741016 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0720912 |
| FNIP1 | folliculin interacting protein 1 | 0.0712444 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0692924 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0687085 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0678032 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0648951 |
| MSN | moesin | 0.0640413 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0612353 |
| ZNF292 | zinc finger protein 292 | 0.0607848 |
| C3 | complement component 3 | 0.054067 |
| SPAG9 | sperm associated antigen 9 | 0.0537928 |
| ENO1 | enolase 1, (alpha) | 0.0531047 |
| GOLGA4 | golgin A4 | 0.0527641 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0527373 |
| PRELID2 | PRELI domain containing 2 | 0.0526728 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0523971 |
| PLIN2 | perilipin 2 | 0.0522524 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0508311 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0492313 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0487219 |
| APP | amyloid beta (A4) precursor protein | 0.048357 |
| FLNB | filamin B, beta | 0.0478777 |
| HELZ | helicase with zinc finger | 0.0478613 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0478505 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0475451 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0474791 |
| FRMD4A | FERM domain containing 4A | 0.0472553 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0470541 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0468685 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0461779 |
| PGK1 | phosphoglycerate kinase 1 | 0.0439232 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0438852 |
| STC2 | stanniocalcin 2 | 0.0436149 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0433555 |
| CDH13 | cadherin 13 | 0.0431187 |
| PFKP | phosphofructokinase, platelet | 0.0430884 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0423785 |
| RPS18 | ribosomal protein S18 | 0.0418953 |
| LOXL2 | lysyl oxidase-like 2 | 0.0415939 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0408707 |
| HMGA1 | high mobility group AT-hook 1 | 0.0404885 |
| DST | dystonin | 0.0404445 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0402819 |
| SQSTM1 | sequestosome 1 | 0.0392614 |
| TNS3 | tensin 3 | 0.0391033 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0390428 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.038909 |
| ATP13A3 | ATPase type 13A3 | 0.0387538 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.038064 |
| FLOT1 | flotillin 1 | 0.0379047 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0378252 |
| WTAP | Wilms tumor 1 associated protein | 0.0372875 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0369871 |
| SEPTIN9 | septin 9 | 0.0369404 |
| CD109 | CD109 molecule | 0.0367755 |
| RPL3 | ribosomal protein L3 | 0.0354268 |
| PKM | pyruvate kinase, muscle | 0.0351315 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0351307 |
| RND3 | Rho family GTPase 3 | 0.0349696 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0348395 |
| LDHA | lactate dehydrogenase A | 0.0345691 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0342924 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0342133 |
| AFDN | afadin, adherens junction formation factor | 0.0337214 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0330176 |
| MMP12 | matrix metallopeptidase 12 | 0.0329229 |
| MCL1 | myeloid cell leukemia 1 | 0.0326919 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0324457 |
| ATXN1 | ataxin 1 | 0.031868 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0317987 |
| RPS12 | ribosomal protein S12 | 0.031785 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.031735 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0313991 |
| PHF21A | PHD finger protein 21A | 0.0313591 |
| NOTCH2 | notch 2 | 0.0313558 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0313264 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0310649 |
| DTNA | dystrobrevin, alpha | 0.0310601 |
| CEP250 | centrosomal protein 250kDa | 0.0309083 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0308594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.129507 |
| GLIS3 | GLIS family zinc finger 3 | -0.110705 |
| BICC1 | BicC family RNA binding protein 1 | -0.105434 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.105218 |
| VCL | vinculin | -0.0746678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0681361 |
| HLA-B | major histocompatibility complex, class I, B | -0.0639914 |
| SLC38A2 | solute carrier family 38, member 2 | -0.048723 |
| CD44 | CD44 molecule (Indian blood group) | -0.0481576 |
| TMSB10 | thymosin beta 10 | -0.0480348 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0465706 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0361978 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0358281 |
| THBS1 | thrombospondin 1 | -0.0357275 |
| NABP1 | nucleic acid binding protein 1 | -0.0351941 |
| RIGI | RNA sensor RIG-I | -0.0351209 |
| HMGA2 | high mobility group AT-hook 2 | -0.033725 |
| EHBP1 | EH domain binding protein 1 | -0.033459 |
| AHNAK | AHNAK nucleoprotein | -0.0325545 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.032357 |
| OSMR | oncostatin M receptor | -0.0313796 |
| TMSB4X | thymosin beta 4, X-linked | -0.0309593 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0288445 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0277595 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0277484 |
| PALLD | palladin, cytoskeletal associated protein | -0.0277024 |
| RPLP1 | ribosomal protein, large, P1 | -0.0264665 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0261604 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0260289 |
| RRBP1 | ribosome binding protein 1 | -0.0259504 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0254483 |
| NRP1 | neuropilin 1 | -0.0240527 |
| FTL | ferritin, light polypeptide | -0.0239394 |
| BPTF | bromodomain PHD finger transcription factor | -0.0234165 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0229683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0223369 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0223054 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222952 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0217087 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0213957 |
| ANXA2 | annexin A2 | -0.0213904 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0212045 |
| XAF1 | XIAP associated factor 1 | -0.0211993 |
| COL1A1 | collagen, type I, alpha 1 | -0.0209465 |
| CAVIN1 | caveolae associated protein 1 | -0.0204498 |
| NF1 | neurofibromin 1 | -0.0200625 |
| RPL36A | ribosomal protein L36a | -0.0198491 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0197959 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0196796 |
| RPS24 | ribosomal protein S24 | -0.0195853 |
| MAP1B | microtubule-associated protein 1B | -0.0192394 |
| ACTG1 | actin gamma 1 | -0.0191313 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0190882 |
| HDAC8 | histone deacetylase 8 | -0.0190546 |
| CNTN6 | contactin 6 | -0.0186697 |
| PMP22 | peripheral myelin protein 22 | -0.0185932 |
| CTSD | cathepsin D | -0.0184043 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0183807 |
| NTN4 | netrin 4 | -0.0181956 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0179865 |
| GPC6 | glypican 6 | -0.0179036 |
| TRIM56 | tripartite motif containing 56 | -0.0179004 |
| CEP112 | centrosomal protein 112kDa | -0.0177649 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0176936 |
| CDK17 | cyclin-dependent kinase 17 | -0.0176811 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0175165 |
| RPL12 | ribosomal protein L12 | -0.0174722 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0174437 |
| TNNC1 | troponin C type 1 (slow) | -0.0174019 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0171084 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0170119 |
| RPL6 | ribosomal protein L6 | -0.0167357 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0166851 |
| TUT7 | terminal uridylyl transferase 7 | -0.0166151 |
| ASTN2 | astrotactin 2 | -0.0165772 |
| MKI67 | marker of proliferation Ki-67 | -0.0164683 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0163713 |
| EGR1 | early growth response 1 | -0.0163136 |
| RPS19 | ribosomal protein S19 | -0.0160534 |
| ETV6 | ets variant 6 | -0.015987 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0158012 |
| RPL32 | ribosomal protein L32 | -0.0157925 |
| PRR11 | proline rich 11 | -0.0157854 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0156684 |
| RPL34 | ribosomal protein L34 | -0.0156619 |
| RPL36 | ribosomal protein L36 | -0.0154927 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0154835 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0154693 |
| CDK12 | cyclin-dependent kinase 12 | -0.0153355 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0153213 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0153126 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.015289 |
| CDCP1 | CUB domain containing protein 1 | -0.0151251 |
| RPLP0 | ribosomal protein, large, P0 | -0.0150624 |
| IER3 | immediate early response 3 | -0.0148645 |
| FOXP1 | forkhead box P1 | -0.0147049 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0146898 |
| TCF12 | transcription factor 12 | -0.0146566 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0146041 |
| TRIM55 | tripartite motif containing 55 | -0.014537 |
