| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WAC | WW domain containing adaptor with coiled-coil | 0.0995792 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0816367 |
| SETD5 | SET domain containing 5 | 0.0783792 |
| TXNRD1 | thioredoxin reductase 1 | 0.0773002 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0726025 |
| TMEM123 | transmembrane protein 123 | 0.0699845 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0693922 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0664659 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0647704 |
| MATR3 | matrin 3 | 0.0646661 |
| RBM39 | RNA binding motif protein 39 | 0.0577131 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0538035 |
| ATP13A3 | ATPase type 13A3 | 0.0537783 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0531322 |
| RNF145 | ring finger protein 145 | 0.0503892 |
| TFG | TRK-fused gene | 0.0497597 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0474591 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0472249 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0465954 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0458652 |
| OLA1 | Obg-like ATPase 1 | 0.0450273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0439843 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0437701 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0430485 |
| TXNIP | thioredoxin interacting protein | 0.041629 |
| ECT2 | epithelial cell transforming 2 | 0.0409112 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0407685 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0395977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0391055 |
| COG5 | component of oligomeric golgi complex 5 | 0.0377161 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0375012 |
| SRP54 | signal recognition particle 54kDa | 0.0373704 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0370435 |
| KIF5B | kinesin family member 5B | 0.0363663 |
| NBAS | neuroblastoma amplified sequence | 0.0359756 |
| ZNF292 | zinc finger protein 292 | 0.0357045 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.03545 |
| FAM13A | family with sequence similarity 13, member A | 0.035182 |
| SGO2 | shugoshin 2 | 0.0345025 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.034382 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0343192 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0337775 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0335774 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0332275 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0330332 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0329168 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.032913 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0327654 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.032753 |
| PHF20 | PHD finger protein 20 | 0.0323319 |
| HBS1L | HBS1-like translational GTPase | 0.032325 |
| NUP58 | nucleoporin 58 | 0.0316821 |
| DIAPH1 | diaphanous-related formin 1 | 0.0314905 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0313768 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0310978 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0309466 |
| DNER | delta/notch-like EGF repeat containing | 0.0308582 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0306318 |
| SPNS1 | spinster homolog 1 (Drosophila) | 0.0305897 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0300356 |
| TPX2 | TPX2, microtubule-associated | 0.0300332 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0299163 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0298381 |
| SPAG9 | sperm associated antigen 9 | 0.0296659 |
| PDS5A | PDS5 cohesin associated factor A | 0.0295241 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0295188 |
| SVIL | supervillin | 0.0294463 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0294249 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0293809 |
| NEMF | nuclear export mediator factor | 0.0289812 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0288993 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0282681 |
| JMJD1C | jumonji domain containing 1C | 0.0281158 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0279359 |
| MORF4L1 | mortality factor 4 like 1 | 0.027915 |
| AXL | AXL receptor tyrosine kinase | 0.0278344 |
| CCNC | cyclin C | 0.0276679 |
| SNX9 | sorting nexin 9 | 0.0276082 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0271768 |
| QKI | QKI, KH domain containing, RNA binding | 0.0269554 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0267273 |
| FAM168A | family with sequence similarity 168, member A | 0.0267139 |
| CAPRIN2 | caprin family member 2 | 0.0265674 |
| TNPO1 | transportin 1 | 0.0265233 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0264435 |
| TPM3 | tropomyosin 3 | 0.0263856 |
| MSN | moesin | 0.0262712 |
| ANXA5 | annexin A5 | 0.0262062 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026175 |
| TUBB | tubulin, beta class I | 0.0261379 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0259441 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0259061 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.025656 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0256419 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0255949 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0255237 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0255201 |
| EXOC5 | exocyst complex component 5 | 0.0255052 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0254986 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0254755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.172481 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134011 |
| TMSB10 | thymosin beta 10 | -0.0981358 |
| INTS6 | integrator complex subunit 6 | -0.0831423 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0826664 |
| HMGA2 | high mobility group AT-hook 2 | -0.0739175 |
| RIGI | RNA sensor RIG-I | -0.0698252 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0671005 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0633099 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0618438 |
| EGR1 | early growth response 1 | -0.0584901 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0555937 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0555338 |
| ATXN1 | ataxin 1 | -0.0513065 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0512536 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0508281 |
| UBC | ubiquitin C | -0.0504238 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0500959 |
| HDAC9 | histone deacetylase 9 | -0.0488342 |
| DST | dystonin | -0.0486913 |
| PRKCA | protein kinase C, alpha | -0.0479601 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.045039 |
| ATM | ATM serine/threonine kinase | -0.0449791 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0446059 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.042482 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0424096 |
| GNAS | GNAS complex locus | -0.0401148 |
| TOP1 | topoisomerase (DNA) I | -0.0398877 |
| RPS27A | ribosomal protein S27a | -0.0398383 |
| FNIP1 | folliculin interacting protein 1 | -0.0396237 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0392414 |
| S100A9 | S100 calcium binding protein A9 | -0.0384426 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0383189 |
| TBCA | tubulin folding cofactor A | -0.0383151 |
| PTMA | prothymosin, alpha | -0.0382745 |
| COL5A1 | collagen, type V, alpha 1 | -0.038035 |
| RPL37 | ribosomal protein L37 | -0.0377376 |
| ATG7 | autophagy related 7 | -0.0370467 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0368585 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0357733 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0356727 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0355913 |
| AEBP2 | AE binding protein 2 | -0.034942 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0348207 |
| GOLGB1 | golgin B1 | -0.0346303 |
| SMYD3 | SET and MYND domain containing 3 | -0.0338098 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0336823 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0334714 |
| FOXO3 | forkhead box O3 | -0.0334709 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0332538 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0331062 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0330877 |
| USP53 | ubiquitin specific peptidase 53 | -0.032671 |
| SQSTM1 | sequestosome 1 | -0.0326268 |
| VCL | vinculin | -0.0320544 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0318562 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0318524 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0317585 |
| FUS | FUS RNA binding protein | -0.0315956 |
| CDK12 | cyclin-dependent kinase 12 | -0.0314067 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0313466 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0310413 |
| RPL32 | ribosomal protein L32 | -0.0310088 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0307864 |
| DPYD | dihydropyrimidine dehydrogenase | -0.030642 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0305929 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0301959 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0300742 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0298291 |
| ITSN2 | intersectin 2 | -0.0292614 |
| RAI14 | retinoic acid induced 14 | -0.0289527 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0289448 |
| NABP1 | nucleic acid binding protein 1 | -0.0289243 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0288966 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0286387 |
| BRD2 | bromodomain containing 2 | -0.0286246 |
| RAB10 | RAB10, member RAS oncogene family | -0.0285017 |
| CREBRF | CREB3 regulatory factor | -0.0283776 |
| WDR70 | WD repeat domain 70 | -0.0283218 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0282003 |
| MTREX | Mtr4 exosome RNA helicase | -0.0281567 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0281454 |
| RPL27A | ribosomal protein L27a | -0.0279129 |
| RPS8 | ribosomal protein S8 | -0.0279105 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.027741 |
| AHNAK | AHNAK nucleoprotein | -0.0277111 |
| METTL16 | methyltransferase like 16 | -0.0276309 |
| LRRC49 | leucine rich repeat containing 49 | -0.027429 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.0270387 |
| VIM | vimentin | -0.0267191 |
| CREBBP | CREB binding protein | -0.0266203 |
| SNX5 | sorting nexin 5 | -0.0265068 |
| MYO10 | myosin X | -0.0264131 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0264028 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0263399 |
| SRP72 | signal recognition particle 72kDa | -0.0261351 |
| OSMR | oncostatin M receptor | -0.0260345 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0258636 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0256878 |
| SETX | senataxin | -0.025575 |
