| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.12937 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.120203 |
| PCBP2 | poly(rC) binding protein 2 | 0.116138 |
| PTMA | prothymosin, alpha | 0.11046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110449 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0953586 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0938656 |
| KRT8 | keratin 8, type II | 0.0847855 |
| KRT18 | keratin 18, type I | 0.0800495 |
| POTEF | POTE ankyrin domain family, member F | 0.0758632 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0751631 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0636294 |
| PGK1 | phosphoglycerate kinase 1 | 0.0565704 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0557067 |
| RPL3 | ribosomal protein L3 | 0.0507752 |
| FAT1 | FAT atypical cadherin 1 | 0.0490089 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0487647 |
| RPS18 | ribosomal protein S18 | 0.0475917 |
| MED13L | mediator complex subunit 13-like | 0.0470951 |
| HLA-A | major histocompatibility complex, class I, A | 0.0440266 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0437374 |
| HMGA1 | high mobility group AT-hook 1 | 0.0430296 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0427517 |
| PLEC | plectin | 0.0409348 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0406121 |
| TPM3 | tropomyosin 3 | 0.039528 |
| CALR | calreticulin | 0.0393973 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0392562 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0392451 |
| ANXA11 | annexin A11 | 0.0391973 |
| ZFP36 | ZFP36 ring finger protein | 0.0385737 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0382293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0380175 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0370534 |
| PKM | pyruvate kinase, muscle | 0.0369054 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0356419 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0349407 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0346491 |
| ADM | adrenomedullin | 0.0346322 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0336062 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0333232 |
| RPS12 | ribosomal protein S12 | 0.0324126 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0322896 |
| SQSTM1 | sequestosome 1 | 0.0319447 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0315469 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0310426 |
| MYO1B | myosin IB | 0.0306934 |
| RPS3 | ribosomal protein S3 | 0.0305202 |
| TMEM123 | transmembrane protein 123 | 0.0300757 |
| NDRG1 | N-myc downstream regulated 1 | 0.0299102 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0297202 |
| YBX1 | Y box binding protein 1 | 0.0293617 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0292723 |
| MATR3 | matrin 3 | 0.028388 |
| MYO5B | myosin VB | 0.0283053 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0282816 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0277715 |
| CTBP2 | C-terminal binding protein 2 | 0.0276065 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0274443 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0270153 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0266681 |
| TPM4 | tropomyosin 4 | 0.026645 |
| RNF149 | ring finger protein 149 | 0.0265632 |
| CCNL1 | cyclin L1 | 0.0264658 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0260252 |
| DHFR | dihydrofolate reductase | 0.0254752 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 0.0254017 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0253543 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0253481 |
| S100A6 | S100 calcium binding protein A6 | 0.0252718 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0249643 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0244965 |
| MSI2 | musashi RNA-binding protein 2 | 0.0244758 |
| B2M | beta-2-microglobulin | 0.0242701 |
| DSPP | dentin sialophosphoprotein | 0.0240341 |
| JUP | junction plakoglobin | 0.0237349 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0233897 |
| KIAA1671 | KIAA1671 | 0.0232811 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232711 |
| OGA | O-GlcNAcase | 0.0232421 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0230587 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0230211 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0228779 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0228375 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0226262 |
| ANXA2 | annexin A2 | 0.0225309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0225036 |
| GNAS | GNAS complex locus | 0.0224426 |
| AHNAK | AHNAK nucleoprotein | 0.0224192 |
| APP | amyloid beta (A4) precursor protein | 0.0223001 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0222076 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0220764 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0219148 |
| FLNA | filamin A, alpha | 0.0218589 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0218156 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0215302 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0215114 |
| ENO1 | enolase 1, (alpha) | 0.0212966 |
| TXNIP | thioredoxin interacting protein | 0.0212928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.141409 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.101768 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.095887 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0876909 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0687098 |
| GOLGB1 | golgin B1 | -0.0586959 |
| JMJD1C | jumonji domain containing 1C | -0.0483457 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0467372 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0467169 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0438995 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0427628 |
| BCL2L1 | BCL2-like 1 | -0.0424581 |
| GOLGA4 | golgin A4 | -0.0419841 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0408854 |
| ZNF207 | zinc finger protein 207 | -0.0403874 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0398722 |
| PKP4 | plakophilin 4 | -0.0395275 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0394776 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0391696 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.038666 |
| MYO1E | myosin IE | -0.0386379 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0381464 |
| EPCAM | epithelial cell adhesion molecule | -0.0357313 |
| RPS6 | ribosomal protein S6 | -0.0355577 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0354439 |
| NUP98 | nucleoporin 98kDa | -0.0353979 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0352813 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0351753 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0348198 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0347875 |
| ACTG1 | actin gamma 1 | -0.0346754 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0340373 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0339549 |
| RPS21 | ribosomal protein S21 | -0.0335082 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0333855 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0333371 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0329751 |
| NF1 | neurofibromin 1 | -0.0327154 |
| VMP1 | vacuole membrane protein 1 | -0.032611 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0323308 |
| EXOC6B | exocyst complex component 6B | -0.0323073 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0322593 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0320449 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0315632 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.031171 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0308743 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0308188 |
| BRD2 | bromodomain containing 2 | -0.03073 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0304923 |
| EHBP1 | EH domain binding protein 1 | -0.030287 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0302321 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0301915 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.030108 |
| CDK13 | cyclin-dependent kinase 13 | -0.0295624 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0293257 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0291552 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0290338 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287541 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0286744 |
| CENPE | centromere protein E, 312kDa | -0.0285355 |
| CEP350 | centrosomal protein 350kDa | -0.0283629 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0282993 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0282494 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0281481 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0281248 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0277498 |
| GPATCH8 | G patch domain containing 8 | -0.0276333 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0274689 |
| NEBL | nebulette | -0.0273614 |
| RPL7A | ribosomal protein L7a | -0.0272721 |
| BPTF | bromodomain PHD finger transcription factor | -0.0269878 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0268755 |
| WWC1 | WW and C2 domain containing 1 | -0.0260648 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0260403 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.025822 |
| HM13 | histocompatibility (minor) 13 | -0.025623 |
| TAOK3 | TAO kinase 3 | -0.0253884 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0253508 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0253036 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0252017 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.025138 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0251249 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0251143 |
| SVIL | supervillin | -0.0248975 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0248533 |
| WDR70 | WD repeat domain 70 | -0.0248525 |
| SETD2 | SET domain containing 2 | -0.0246363 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0244123 |
| STK4 | serine/threonine kinase 4 | -0.0242854 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0242206 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.023568 |
| OXR1 | oxidation resistance 1 | -0.0235065 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0233432 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0233335 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0231651 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0230649 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | -0.023021 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0229871 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0228256 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0227686 |
