| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.12615 |
| RPL3 | ribosomal protein L3 | 0.0946433 |
| RPS18 | ribosomal protein S18 | 0.0835872 |
| PCBP2 | poly(rC) binding protein 2 | 0.0822129 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0721408 |
| EREG | epiregulin | 0.0612902 |
| CPOX | coproporphyrinogen oxidase | 0.0572782 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0564667 |
| FLOT1 | flotillin 1 | 0.0551039 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0538639 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0535892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0531592 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0504054 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0494116 |
| LMO7 | LIM domain 7 | 0.0492537 |
| NUP58 | nucleoporin 58 | 0.0467824 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.046515 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.044448 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0440631 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0437506 |
| DIAPH1 | diaphanous-related formin 1 | 0.0413394 |
| RPS12 | ribosomal protein S12 | 0.0412425 |
| NDRG1 | N-myc downstream regulated 1 | 0.0405677 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0388274 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0387171 |
| COPA | coatomer protein complex, subunit alpha | 0.0376796 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0375562 |
| ANXA11 | annexin A11 | 0.0371776 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0356767 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.035645 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0354147 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351072 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0350278 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0343566 |
| LDHA | lactate dehydrogenase A | 0.0336119 |
| FOSL1 | FOS-like antigen 1 | 0.0330706 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0323892 |
| LAMC2 | laminin, gamma 2 | 0.0323579 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0322884 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0319822 |
| SQSTM1 | sequestosome 1 | 0.0317729 |
| SNX9 | sorting nexin 9 | 0.0316295 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0310296 |
| ANXA1 | annexin A1 | 0.0308878 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0306443 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0304182 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.030324 |
| RREB1 | ras responsive element binding protein 1 | 0.0301682 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0298332 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.029457 |
| TPM3 | tropomyosin 3 | 0.0294163 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0291357 |
| FAT1 | FAT atypical cadherin 1 | 0.0287359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0284744 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283022 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0274008 |
| ZFP36 | ZFP36 ring finger protein | 0.027206 |
| TFRC | transferrin receptor | 0.0271116 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0270705 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.026771 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0264712 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0264615 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0263614 |
| GPR15 | G protein-coupled receptor 15 | 0.0261648 |
| RPS3 | ribosomal protein S3 | 0.0259494 |
| DSPP | dentin sialophosphoprotein | 0.0256037 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025403 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.025356 |
| CCNL1 | cyclin L1 | 0.0253549 |
| SETD5 | SET domain containing 5 | 0.0253177 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0251334 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0247945 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0246789 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0244839 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0244269 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0244093 |
| MYO5B | myosin VB | 0.0243564 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0243552 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.024212 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0240463 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.023929 |
| RNF145 | ring finger protein 145 | 0.023843 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0235402 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02354 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234538 |
| TXNIP | thioredoxin interacting protein | 0.0232706 |
| TMEM123 | transmembrane protein 123 | 0.0232344 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0231098 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0228646 |
| KRT18 | keratin 18, type I | 0.0223977 |
| CLIC4 | chloride intracellular channel 4 | 0.0221822 |
| CALR | calreticulin | 0.0221813 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0220413 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0218932 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0216559 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0215261 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.021417 |
| EPHA2 | EPH receptor A2 | 0.0213446 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0213164 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0211561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15189 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.122587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106506 |
| RPL35A | ribosomal protein L35a | -0.0824739 |
| TMSB10 | thymosin beta 10 | -0.0806042 |
| RPLP1 | ribosomal protein, large, P1 | -0.0775542 |
| OXR1 | oxidation resistance 1 | -0.0666624 |
| RPS24 | ribosomal protein S24 | -0.0551316 |
| RPS6 | ribosomal protein S6 | -0.0507802 |
| RPS8 | ribosomal protein S8 | -0.0478069 |
| RAD51B | RAD51 paralog B | -0.0431903 |
| EMP1 | epithelial membrane protein 1 | -0.0406094 |
| HMGA2 | high mobility group AT-hook 2 | -0.0404753 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401992 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0369982 |
| CDK13 | cyclin-dependent kinase 13 | -0.0362454 |
| RPL34 | ribosomal protein L34 | -0.0341619 |
| ACTG1 | actin gamma 1 | -0.0341179 |
| RPL8 | ribosomal protein L8 | -0.0340678 |
| RPL32 | ribosomal protein L32 | -0.032255 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0312924 |
| RPLP0 | ribosomal protein, large, P0 | -0.030791 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0306954 |
| RPS15 | ribosomal protein S15 | -0.0305521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304596 |
| RPL19 | ribosomal protein L19 | -0.0300727 |
| UBE3C | ubiquitin protein ligase E3C | -0.0300287 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0299967 |
| RPS28 | ribosomal protein S28 | -0.0299292 |
| RPLP2 | ribosomal protein, large, P2 | -0.0297641 |
| PHF14 | PHD finger protein 14 | -0.0297243 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0294049 |
| RPL7A | ribosomal protein L7a | -0.0293234 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0287428 |
| RPL13A | ribosomal protein L13a | -0.0287028 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.028336 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0276919 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0276411 |
| RNF43 | ring finger protein 43 | -0.0273152 |
| PDLIM5 | PDZ and LIM domain 5 | -0.027047 |
| JMJD1C | jumonji domain containing 1C | -0.0267119 |
| BPTF | bromodomain PHD finger transcription factor | -0.0265647 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0262641 |
| TNPO1 | transportin 1 | -0.0261589 |
| NF1 | neurofibromin 1 | -0.0258866 |
| THOC2 | THO complex 2 | -0.0258251 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0257026 |
| RPL4 | ribosomal protein L4 | -0.0254525 |
| ARF1 | ADP-ribosylation factor 1 | -0.0253882 |
| S100A9 | S100 calcium binding protein A9 | -0.0252163 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0251216 |
| PERP | PERP, TP53 apoptosis effector | -0.024768 |
| RPL30 | ribosomal protein L30 | -0.0246247 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0244762 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0244207 |
| RPS25 | ribosomal protein S25 | -0.024108 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0239702 |
| CCNH | cyclin H | -0.0239511 |
| RPL28 | ribosomal protein L28 | -0.0238284 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0237793 |
| TUT4 | terminal uridylyl transferase 4 | -0.0236963 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0235033 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0231627 |
| ZNF207 | zinc finger protein 207 | -0.0230228 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0230163 |
| CENPE | centromere protein E, 312kDa | -0.0228776 |
| MT1X | metallothionein 1X | -0.0222772 |
| RPS29 | ribosomal protein S29 | -0.0222757 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0222188 |
| RPL6 | ribosomal protein L6 | -0.0222037 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0220578 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0218513 |
| OGA | O-GlcNAcase | -0.0216698 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0215982 |
| IER3 | immediate early response 3 | -0.021257 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0211399 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0208342 |
| RPL5 | ribosomal protein L5 | -0.0207143 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0205957 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0205846 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0205191 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0205146 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0204653 |
| FOXN3 | forkhead box N3 | -0.0203583 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0201514 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0201437 |
| ECT2 | epithelial cell transforming 2 | -0.0200285 |
| SERINC5 | serine incorporator 5 | -0.0200068 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0199916 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0198824 |
| USP34 | ubiquitin specific peptidase 34 | -0.0198602 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0198399 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0196642 |
| CUX1 | cut-like homeobox 1 | -0.0196402 |
| TCF12 | transcription factor 12 | -0.019602 |
| NEMF | nuclear export mediator factor | -0.0195336 |
| RRBP1 | ribosome binding protein 1 | -0.0195325 |
| RNF216 | ring finger protein 216 | -0.0193696 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.019353 |
| ACTN4 | actinin, alpha 4 | -0.0190153 |
