| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.116529 |
| PCBP2 | poly(rC) binding protein 2 | 0.106215 |
| PLEC | plectin | 0.0863463 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0853379 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0810287 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0800112 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0668419 |
| RPL3 | ribosomal protein L3 | 0.0646753 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0636751 |
| RPS18 | ribosomal protein S18 | 0.059897 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0573871 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0529281 |
| SEPTIN9 | septin 9 | 0.0497941 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0489804 |
| HDAC4 | histone deacetylase 4 | 0.0487881 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433152 |
| PTMA | prothymosin, alpha | 0.0428816 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0425813 |
| HPCAL1 | hippocalcin-like 1 | 0.0422559 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0422501 |
| KRT18 | keratin 18, type I | 0.0421905 |
| RPS12 | ribosomal protein S12 | 0.0383392 |
| AHNAK | AHNAK nucleoprotein | 0.0377929 |
| FLNB | filamin B, beta | 0.0374411 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0373702 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0359162 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0357903 |
| NAV2 | neuron navigator 2 | 0.035669 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0355949 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0354172 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0353505 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0352191 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0342763 |
| ITGB4 | integrin, beta 4 | 0.0342543 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0341083 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0336801 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.033622 |
| APP | amyloid beta (A4) precursor protein | 0.0334065 |
| ENO1 | enolase 1, (alpha) | 0.0331269 |
| ANKRD10 | ankyrin repeat domain 10 | 0.033109 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0330774 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0330628 |
| ITGA6 | integrin, alpha 6 | 0.0330494 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0328249 |
| FRMD5 | FERM domain containing 5 | 0.0327458 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0325244 |
| KRT8 | keratin 8, type II | 0.0322335 |
| IPO7 | importin 7 | 0.0319919 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0319851 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0316111 |
| ATP13A3 | ATPase type 13A3 | 0.0312181 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0310875 |
| FMNL2 | formin-like 2 | 0.0308606 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0306457 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0305481 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0302349 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0299511 |
| KRT5 | keratin 5, type II | 0.0296944 |
| VCL | vinculin | 0.0295054 |
| CORO1C | coronin, actin binding protein, 1C | 0.0294233 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0294225 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0292082 |
| RPS3 | ribosomal protein S3 | 0.0291583 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0284909 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.028348 |
| ANXA11 | annexin A11 | 0.0278254 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0277739 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0272841 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0269287 |
| ACTN1 | actinin, alpha 1 | 0.0267109 |
| NONO | non-POU domain containing, octamer-binding | 0.0264702 |
| RPS7 | ribosomal protein S7 | 0.0264539 |
| RASA3 | RAS p21 protein activator 3 | 0.0263912 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0263392 |
| ASPH | aspartate beta-hydroxylase | 0.0263093 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.025801 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0257902 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0257744 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0256166 |
| MSN | moesin | 0.0255833 |
| SQSTM1 | sequestosome 1 | 0.0255261 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0254647 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0253319 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0253248 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0252292 |
| RPL37A | ribosomal protein L37a | 0.0251298 |
| MATR3 | matrin 3 | 0.0248621 |
| MED13L | mediator complex subunit 13-like | 0.0248038 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0247577 |
| FLNA | filamin A, alpha | 0.0246114 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0246039 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0243851 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.023997 |
| HMGA1 | high mobility group AT-hook 1 | 0.0238611 |
| MSI2 | musashi RNA-binding protein 2 | 0.0235774 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0234398 |
| NHSL1 | NHS-like 1 | 0.0234292 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0233314 |
| SMAD3 | SMAD family member 3 | 0.0232912 |
| DIAPH1 | diaphanous-related formin 1 | 0.0231717 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295116 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0903127 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0756545 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0704819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0645298 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0634012 |
| RPL35A | ribosomal protein L35a | -0.0483007 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0469092 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0464114 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0427543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0422308 |
| PFN1 | profilin 1 | -0.0421132 |
| EGR1 | early growth response 1 | -0.0412315 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0410718 |
| OXR1 | oxidation resistance 1 | -0.0396477 |
| RPS6 | ribosomal protein S6 | -0.0381425 |
| BPTF | bromodomain PHD finger transcription factor | -0.0376777 |
| SMC4 | structural maintenance of chromosomes 4 | -0.036888 |
| PERP | PERP, TP53 apoptosis effector | -0.0367029 |
| VIM | vimentin | -0.0347263 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0340002 |
| TUBA1B | tubulin, alpha 1b | -0.0335005 |
| CENPF | centromere protein F, 350/400kDa | -0.0334419 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0323696 |
| VDAC1 | voltage-dependent anion channel 1 | -0.030878 |
| S100A10 | S100 calcium binding protein A10 | -0.0298121 |
| MT2A | metallothionein 2A | -0.0284251 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0264513 |
| ARF4 | ADP-ribosylation factor 4 | -0.0261833 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0260831 |
| RPS8 | ribosomal protein S8 | -0.0259569 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0258728 |
| FOXP1 | forkhead box P1 | -0.025297 |
| RPL7A | ribosomal protein L7a | -0.0250704 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0244665 |
| MORF4L2 | mortality factor 4 like 2 | -0.0236079 |
| PROX1 | prospero homeobox 1 | -0.0232303 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0230466 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.02303 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0228421 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225707 |
| TMSB10 | thymosin beta 10 | -0.0224932 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0223463 |
| DIAPH3 | diaphanous-related formin 3 | -0.0223259 |
| RPL28 | ribosomal protein L28 | -0.0221516 |
| RPS15 | ribosomal protein S15 | -0.0220441 |
| GOLGB1 | golgin B1 | -0.0220121 |
| DST | dystonin | -0.0217911 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0216319 |
| RPL8 | ribosomal protein L8 | -0.0215127 |
| RPLP1 | ribosomal protein, large, P1 | -0.0210965 |
| UTRN | utrophin | -0.020972 |
| S100A9 | S100 calcium binding protein A9 | -0.0208998 |
| RPL39 | ribosomal protein L39 | -0.0208688 |
| MT1X | metallothionein 1X | -0.0206818 |
| RPS5 | ribosomal protein S5 | -0.0205262 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0204863 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.020274 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0199888 |
| INTS6 | integrator complex subunit 6 | -0.0196741 |
| PCM1 | pericentriolar material 1 | -0.0196713 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0194745 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0193069 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0192914 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0192267 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0191633 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.019152 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0188959 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0187011 |
| RPS16 | ribosomal protein S16 | -0.0186236 |
| RPL27A | ribosomal protein L27a | -0.0185321 |
| RPS24 | ribosomal protein S24 | -0.018468 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0182831 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0181889 |
| BMP5 | bone morphogenetic protein 5 | -0.0181857 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0179983 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.017991 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0179356 |
| UBXN4 | UBX domain protein 4 | -0.0178424 |
| RPL36A | ribosomal protein L36a | -0.0177529 |
| SVIL | supervillin | -0.0173094 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0173073 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0172239 |
| CBX3 | chromobox homolog 3 | -0.0172098 |
| RBMX | RNA binding motif protein, X-linked | -0.0171766 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0168816 |
| RPS21 | ribosomal protein S21 | -0.0168029 |
| EMP1 | epithelial membrane protein 1 | -0.0167898 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0167082 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0166564 |
| CCDC88A | coiled-coil domain containing 88A | -0.0166564 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0166178 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0165007 |
| KPNB1 | karyopherin (importin) beta 1 | -0.016379 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0163473 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0162191 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0161069 |
| RPS25 | ribosomal protein S25 | -0.0159981 |
| ZNF292 | zinc finger protein 292 | -0.0159178 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0157793 |
