| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dapagliflozin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0773488 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0739628 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0731642 |
| RUNX1 | runt-related transcription factor 1 | 0.0678221 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0617773 |
| ITGA6 | integrin, alpha 6 | 0.0606516 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0589042 |
| RNF43 | ring finger protein 43 | 0.0551258 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0548354 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0475557 |
| SPATA13 | spermatogenesis associated 13 | 0.0474287 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0465544 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0461011 |
| AOPEP | aminopeptidase O (putative) | 0.0436631 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0434792 |
| MECOM | MDS1 and EVI1 complex locus | 0.0426315 |
| TRIM2 | tripartite motif containing 2 | 0.0415293 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.040609 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0396708 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0393653 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0380767 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0364404 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0363009 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0361854 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0358523 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0352156 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0344794 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0344225 |
| TJP2 | tight junction protein 2 | 0.0339456 |
| DIAPH3 | diaphanous-related formin 3 | 0.0338054 |
| ETNK1 | ethanolamine kinase 1 | 0.0330581 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0329054 |
| YAP1 | Yes-associated protein 1 | 0.0327895 |
| NEBL | nebulette | 0.0327249 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0324504 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0323667 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0322397 |
| DHFR | dihydrofolate reductase | 0.0317415 |
| ATP11A | ATPase, class VI, type 11A | 0.0314924 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0312557 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0300955 |
| MSI2 | musashi RNA-binding protein 2 | 0.0298095 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0297679 |
| FOXP1 | forkhead box P1 | 0.0294791 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0293885 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0288838 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0288483 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0286312 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0285204 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0284334 |
| ATP10B | ATPase, class V, type 10B | 0.0282705 |
| PTEN | phosphatase and tensin homolog | 0.0282097 |
| UBAC2 | UBA domain containing 2 | 0.0274439 |
| ZNRF3 | zinc and ring finger 3 | 0.0273944 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0272113 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0267181 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0265902 |
| DUSP16 | dual specificity phosphatase 16 | 0.0265072 |
| ALPK1 | alpha-kinase 1 | 0.0264761 |
| IL20RA | interleukin 20 receptor, alpha | 0.0264548 |
| MEIS2 | Meis homeobox 2 | 0.0263274 |
| FNIP2 | folliculin interacting protein 2 | 0.0261279 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0260338 |
| ETV6 | ets variant 6 | 0.0256009 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0253931 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0252629 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0251519 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0249464 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0248608 |
| PRKCA | protein kinase C, alpha | 0.0247555 |
| ATXN1 | ataxin 1 | 0.024461 |
| ABHD2 | abhydrolase domain containing 2 | 0.0244063 |
| EHF | ets homologous factor | 0.0243076 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0241253 |
| STK24 | serine/threonine kinase 24 | 0.02352 |
| HDAC4 | histone deacetylase 4 | 0.0228509 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0227685 |
| MLPH | melanophilin | 0.022636 |
| COG6 | component of oligomeric golgi complex 6 | 0.0225111 |
| TMEM51 | transmembrane protein 51 | 0.022418 |
| RBM26 | RNA binding motif protein 26 | 0.0223107 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0222403 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0220771 |
| EXOC4 | exocyst complex component 4 | 0.0215017 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.021501 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0214948 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0213423 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0212235 |
| DSCAM | Down syndrome cell adhesion molecule | 0.021206 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0210239 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0209745 |
| NCKAP5 | NCK-associated protein 5 | 0.0208968 |
| AHNAK | AHNAK nucleoprotein | 0.0208546 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0208465 |
| PRELID2 | PRELI domain containing 2 | 0.020683 |
| TMEM39A | transmembrane protein 39A | 0.0206287 |
| RLIM | ring finger protein, LIM domain interacting | 0.0205795 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0205347 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0204481 |
| TMEM62 | transmembrane protein 62 | 0.0204247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.237073 |
| B2M | beta-2-microglobulin | -0.146558 |
| INTS6 | integrator complex subunit 6 | -0.131861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116707 |
| EGR1 | early growth response 1 | -0.107782 |
| PTMA | prothymosin, alpha | -0.0998336 |
| EZR | ezrin | -0.0946643 |
| VCL | vinculin | -0.0932807 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0906011 |
| ANXA2 | annexin A2 | -0.0894229 |
| HLA-B | major histocompatibility complex, class I, B | -0.0850864 |
| LCN2 | lipocalin 2 | -0.0792995 |
| PLSCR2 | phospholipid scramblase 2 | -0.0742549 |
| MUC20 | mucin 20, cell surface associated | -0.0690281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0686518 |
| SQSTM1 | sequestosome 1 | -0.0685924 |
| FTL | ferritin, light polypeptide | -0.0673229 |
| LYZ | lysozyme | -0.0643302 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0636234 |
| RPL35A | ribosomal protein L35a | -0.062232 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.06108 |
| ACTG1 | actin gamma 1 | -0.060895 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0606566 |
| UBC | ubiquitin C | -0.0604115 |
| AREG | amphiregulin | -0.0572503 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.054386 |
| PKM | pyruvate kinase, muscle | -0.0541963 |
| TMSB10 | thymosin beta 10 | -0.0541325 |
| RPL34 | ribosomal protein L34 | -0.0537666 |
| SP100 | SP100 nuclear antigen | -0.0523232 |
| XAF1 | XIAP associated factor 1 | -0.0514979 |
| MCL1 | myeloid cell leukemia 1 | -0.0509102 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0508913 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0508859 |
| RPS8 | ribosomal protein S8 | -0.0499204 |
| RPS6 | ribosomal protein S6 | -0.0497942 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0494579 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0485769 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0469433 |
| PERP | PERP, TP53 apoptosis effector | -0.0467475 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0467166 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.045696 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0451622 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0448102 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0435521 |
| PHF3 | PHD finger protein 3 | -0.0428169 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427039 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0422696 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0420977 |
| MORF4L2 | mortality factor 4 like 2 | -0.0418798 |
| RPL23 | ribosomal protein L23 | -0.0418186 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0403234 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0402907 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0380908 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0378415 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0377614 |
| RPS24 | ribosomal protein S24 | -0.0375204 |
| JUN | jun proto-oncogene | -0.0371831 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0364419 |
| EPCAM | epithelial cell adhesion molecule | -0.0364041 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0359663 |
| IRF1 | interferon regulatory factor 1 | -0.0359236 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0354665 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0349306 |
| S100A6 | S100 calcium binding protein A6 | -0.0345714 |
| RPLP0 | ribosomal protein, large, P0 | -0.0345701 |
| HM13 | histocompatibility (minor) 13 | -0.0344099 |
| LDHA | lactate dehydrogenase A | -0.0341776 |
| NDRG1 | N-myc downstream regulated 1 | -0.0341186 |
| RPL37 | ribosomal protein L37 | -0.0340882 |
| ENO1 | enolase 1, (alpha) | -0.0339726 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0336704 |
| POU2F2 | POU class 2 homeobox 2 | -0.0335655 |
| ARF1 | ADP-ribosylation factor 1 | -0.0335571 |
| RPL26 | ribosomal protein L26 | -0.0335438 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0330336 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0327619 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0325056 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0324758 |
| MT2A | metallothionein 2A | -0.0324359 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.032424 |
| RPL11 | ribosomal protein L11 | -0.0324024 |
| CSTB | cystatin B (stefin B) | -0.0323272 |
| S100A10 | S100 calcium binding protein A10 | -0.031443 |
| RPL37A | ribosomal protein L37a | -0.0313354 |
| TUFT1 | tuftelin 1 | -0.0312653 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0312108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0306932 |
| PGK1 | phosphoglycerate kinase 1 | -0.0306487 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.030636 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0306062 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0305254 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0302084 |
| UBAP2 | ubiquitin associated protein 2 | -0.0299987 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0296155 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0294946 |
| HLA-E | major histocompatibility complex, class I, E | -0.0294851 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0294534 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0294461 |
| RIGI | RNA sensor RIG-I | -0.0291522 |
