| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dapagliflozin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.159304 |
| BCL2L1 | BCL2-like 1 | 0.072126 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0698397 |
| AHNAK | AHNAK nucleoprotein | 0.0695015 |
| PLEC | plectin | 0.0690955 |
| FOXO1 | forkhead box O1 | 0.068281 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0649441 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0570612 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0519473 |
| SULF1 | sulfatase 1 | 0.0489439 |
| ITGA6 | integrin, alpha 6 | 0.0453956 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0451006 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0443027 |
| OSMR | oncostatin M receptor | 0.0430964 |
| NRG1 | neuregulin 1 | 0.0420167 |
| RIN2 | Ras and Rab interactor 2 | 0.0412725 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0388299 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0386502 |
| MSN | moesin | 0.0381383 |
| SMAD3 | SMAD family member 3 | 0.0356434 |
| MYOF | myoferlin | 0.0352403 |
| VCL | vinculin | 0.0343761 |
| PRELID2 | PRELI domain containing 2 | 0.0335926 |
| MECOM | MDS1 and EVI1 complex locus | 0.0330917 |
| FOXP1 | forkhead box P1 | 0.0327737 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0326651 |
| AOPEP | aminopeptidase O (putative) | 0.032566 |
| NEK7 | NIMA-related kinase 7 | 0.032559 |
| BLCAP | bladder cancer associated protein | 0.0317976 |
| PODXL | podocalyxin-like | 0.0315964 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.031105 |
| CAPRIN2 | caprin family member 2 | 0.0309847 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0306354 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0302456 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0300941 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0296339 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0295999 |
| SMYD3 | SET and MYND domain containing 3 | 0.0289804 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0271195 |
| PLAT | plasminogen activator, tissue | 0.0269205 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0268228 |
| CUL4B | cullin 4B | 0.0267771 |
| METTL15 | methyltransferase like 15 | 0.0266793 |
| RASAL2 | RAS protein activator like 2 | 0.0264317 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0259784 |
| SEPTIN9 | septin 9 | 0.0257751 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0251428 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0250639 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0249066 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0249041 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0248517 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0245542 |
| CDK6 | cyclin-dependent kinase 6 | 0.0245501 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244383 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0244094 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0240824 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0237943 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0237907 |
| EFNA5 | ephrin-A5 | 0.0235804 |
| LUZP1 | leucine zipper protein 1 | 0.0222136 |
| SLTM | SAFB-like, transcription modulator | 0.0221046 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0218131 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0218117 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0217266 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0213707 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0213334 |
| EXOC6B | exocyst complex component 6B | 0.0212548 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0211481 |
| TGM2 | transglutaminase 2 | 0.0209429 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0207515 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0207495 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0205976 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0203868 |
| EHBP1 | EH domain binding protein 1 | 0.0201319 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0200663 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0200364 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0199587 |
| PTK2 | protein tyrosine kinase 2 | 0.0199105 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0198945 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0198015 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0196347 |
| EXOC4 | exocyst complex component 4 | 0.0195702 |
| COG5 | component of oligomeric golgi complex 5 | 0.0193887 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0189587 |
| PALLD | palladin, cytoskeletal associated protein | 0.0189459 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0189426 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0188064 |
| MYO9A | myosin IXA | 0.018804 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0182928 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0182564 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0181402 |
| CMIP | c-Maf inducing protein | 0.0180235 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0180174 |
| ANO6 | anoctamin 6 | 0.0179421 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0178936 |
| SERINC3 | serine incorporator 3 | 0.017774 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0177646 |
| LOXL2 | lysyl oxidase-like 2 | 0.0175827 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0175728 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0175092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0763508 |
| PTMA | prothymosin, alpha | -0.0761993 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0688579 |
| ANXA1 | annexin A1 | -0.0663954 |
| RPS6 | ribosomal protein S6 | -0.0640853 |
| MT2A | metallothionein 2A | -0.0577878 |
| RPS8 | ribosomal protein S8 | -0.0546269 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0537997 |
| B2M | beta-2-microglobulin | -0.0534028 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0487653 |
| TMSB10 | thymosin beta 10 | -0.0480875 |
| RPS21 | ribosomal protein S21 | -0.0480549 |
| S100A10 | S100 calcium binding protein A10 | -0.0469472 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0460778 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0442655 |
| RPLP2 | ribosomal protein, large, P2 | -0.0440206 |
| RPLP1 | ribosomal protein, large, P1 | -0.0426457 |
| KRT17 | keratin 17, type I | -0.0412008 |
| RPS19 | ribosomal protein S19 | -0.0400559 |
| RPL11 | ribosomal protein L11 | -0.0362665 |
| SQSTM1 | sequestosome 1 | -0.033397 |
| YBX1 | Y box binding protein 1 | -0.0331375 |
| RPS12 | ribosomal protein S12 | -0.032936 |
| RPS13 | ribosomal protein S13 | -0.0328764 |
| RPL23 | ribosomal protein L23 | -0.0318034 |
| RPS3 | ribosomal protein S3 | -0.0308869 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0307117 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303233 |
| RPL8 | ribosomal protein L8 | -0.0298807 |
| RPL19 | ribosomal protein L19 | -0.0293143 |
| RPL12 | ribosomal protein L12 | -0.0292341 |
| RPL37 | ribosomal protein L37 | -0.0285168 |
| FTL | ferritin, light polypeptide | -0.0279382 |
| LMNA | lamin A/C | -0.0275187 |
| S100A6 | S100 calcium binding protein A6 | -0.0274435 |
| RPS25 | ribosomal protein S25 | -0.0274413 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0267982 |
| RPL26 | ribosomal protein L26 | -0.0257896 |
| RPL35A | ribosomal protein L35a | -0.0251978 |
| S100A9 | S100 calcium binding protein A9 | -0.0248894 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.024874 |
| RPL34 | ribosomal protein L34 | -0.0240791 |
| SQLE | squalene epoxidase | -0.023998 |
| S100A2 | S100 calcium binding protein A2 | -0.0236624 |
| RPL31 | ribosomal protein L31 | -0.0234446 |
| PLS3 | plastin 3 | -0.0232666 |
| RPL37A | ribosomal protein L37a | -0.0232175 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0230727 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0227777 |
| RPL30 | ribosomal protein L30 | -0.0226824 |
| RPS29 | ribosomal protein S29 | -0.0226344 |
| RPL27A | ribosomal protein L27a | -0.0226023 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0223073 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.022036 |
| GNAS | GNAS complex locus | -0.0216705 |
| RPS20 | ribosomal protein S20 | -0.0215835 |
| RPL13A | ribosomal protein L13a | -0.0215083 |
| RPL36 | ribosomal protein L36 | -0.0213945 |
| RPL35 | ribosomal protein L35 | -0.0211767 |
| RPS2 | ribosomal protein S2 | -0.0210347 |
| RACK1 | receptor for activated C kinase 1 | -0.0207936 |
| RPS23 | ribosomal protein S23 | -0.0204743 |
| DSTN | destrin (actin depolymerizing factor) | -0.0204688 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0204315 |
| RPS14 | ribosomal protein S14 | -0.0202899 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0202469 |
| RPS27 | ribosomal protein S27 | -0.0200584 |
| MT1X | metallothionein 1X | -0.0199047 |
| RPL5 | ribosomal protein L5 | -0.0198932 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.019355 |
| RPL28 | ribosomal protein L28 | -0.0192668 |
| LDHA | lactate dehydrogenase A | -0.0190648 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0189758 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0188176 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0187363 |
| S100A11 | S100 calcium binding protein A11 | -0.0184723 |
| RPS27A | ribosomal protein S27a | -0.0179475 |
| HMGA1 | high mobility group AT-hook 1 | -0.0179306 |
| RPS24 | ribosomal protein S24 | -0.0177579 |
| STC1 | stanniocalcin 1 | -0.0176499 |
| RPL32 | ribosomal protein L32 | -0.0176089 |
| CD44 | CD44 molecule (Indian blood group) | -0.0175751 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0174947 |
| RPL7A | ribosomal protein L7a | -0.0174531 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0173811 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0173579 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0171576 |
| HLA-A | major histocompatibility complex, class I, A | -0.0171264 |
| ADM | adrenomedullin | -0.0170221 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0168401 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0167367 |
| RPL9 | ribosomal protein L9 | -0.0167315 |
| RPS16 | ribosomal protein S16 | -0.0164936 |
| RPL39 | ribosomal protein L39 | -0.0162337 |
| RPL36A | ribosomal protein L36a | -0.016199 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0161443 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0159946 |
| RPLP0 | ribosomal protein, large, P0 | -0.0159733 |
| RPL21 | ribosomal protein L21 | -0.0158802 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0158724 |
