| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dapagliflozin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.263857 |
| FN1 | fibronectin 1 | 0.219419 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0939336 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.080163 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0776886 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0776725 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0759687 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0688954 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0616674 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0592897 |
| NAV2 | neuron navigator 2 | 0.058327 |
| JMJD1C | jumonji domain containing 1C | 0.0493202 |
| SMAD3 | SMAD family member 3 | 0.0482448 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0475282 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0452589 |
| OGA | O-GlcNAcase | 0.0452499 |
| MSN | moesin | 0.0430755 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0427397 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0412643 |
| ATXN1 | ataxin 1 | 0.0411582 |
| SFTPA2 | surfactant protein A2 | 0.04006 |
| SPAG9 | sperm associated antigen 9 | 0.0400445 |
| MYOF | myoferlin | 0.04001 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0397444 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0390735 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0389578 |
| FLNB | filamin B, beta | 0.0389335 |
| MKI67 | marker of proliferation Ki-67 | 0.0385736 |
| VCL | vinculin | 0.0384165 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0376173 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.037375 |
| DST | dystonin | 0.0372272 |
| ANLN | anillin, actin binding protein | 0.0365814 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0352987 |
| ZNF292 | zinc finger protein 292 | 0.0332695 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0326093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324933 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0322628 |
| TNS3 | tensin 3 | 0.0319365 |
| FNIP1 | folliculin interacting protein 1 | 0.0314431 |
| APP | amyloid beta (A4) precursor protein | 0.0307993 |
| FLNA | filamin A, alpha | 0.0307953 |
| HELZ | helicase with zinc finger | 0.0303655 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0295659 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0294661 |
| PDE10A | phosphodiesterase 10A | 0.029448 |
| WTAP | Wilms tumor 1 associated protein | 0.0286885 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.02831 |
| PRELID2 | PRELI domain containing 2 | 0.0281873 |
| TSC22D2 | TSC22 domain family, member 2 | 0.028163 |
| PTK2 | protein tyrosine kinase 2 | 0.0277943 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0274783 |
| FRMD5 | FERM domain containing 5 | 0.0271901 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0269826 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0264282 |
| ARRDC3 | arrestin domain containing 3 | 0.0261838 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0261346 |
| SBF2 | SET binding factor 2 | 0.0260855 |
| DIAPH3 | diaphanous-related formin 3 | 0.0252556 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0250425 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0250019 |
| RUNX1 | runt-related transcription factor 1 | 0.0249861 |
| CENPF | centromere protein F, 350/400kDa | 0.0248532 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0246279 |
| SDC4 | syndecan 4 | 0.0246071 |
| ZNF451 | zinc finger protein 451 | 0.0235474 |
| TGFB2 | transforming growth factor, beta 2 | 0.0231472 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0230164 |
| TPX2 | TPX2, microtubule-associated | 0.0228317 |
| ATP13A3 | ATPase type 13A3 | 0.0227224 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0226801 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0226711 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0226233 |
| VCAN | versican | 0.0221482 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0221278 |
| VMP1 | vacuole membrane protein 1 | 0.0220888 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0217647 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0215777 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.021367 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0212186 |
| MAP4 | microtubule-associated protein 4 | 0.0208283 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0207929 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0207261 |
| RLF | rearranged L-myc fusion | 0.0206259 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0205847 |
| AHR | aryl hydrocarbon receptor | 0.0201342 |
| RNF24 | ring finger protein 24 | 0.0200228 |
| XPO1 | exportin 1 | 0.0198982 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0196491 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0195229 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0192825 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.019279 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0191881 |
| PHIP | pleckstrin homology domain interacting protein | 0.0191656 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0191212 |
| KIF13A | kinesin family member 13A | 0.0191006 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0190683 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0189763 |
| TGM2 | transglutaminase 2 | 0.0188548 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0188523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.241017 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.108579 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.107438 |
| HLA-B | major histocompatibility complex, class I, B | -0.0938136 |
| IER3 | immediate early response 3 | -0.0845044 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0838707 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0746483 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.069294 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0605565 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0599203 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0588573 |
| FTL | ferritin, light polypeptide | -0.0582125 |
| TMSB10 | thymosin beta 10 | -0.0573684 |
| LDHA | lactate dehydrogenase A | -0.0542646 |
| RPS6 | ribosomal protein S6 | -0.0535109 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0529311 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0527263 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0521972 |
| MT2A | metallothionein 2A | -0.0497766 |
| CDH13 | cadherin 13 | -0.0488554 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0455447 |
| RPS12 | ribosomal protein S12 | -0.0453717 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0436624 |
| SQSTM1 | sequestosome 1 | -0.0411344 |
| HLA-A | major histocompatibility complex, class I, A | -0.0410702 |
| RPS8 | ribosomal protein S8 | -0.0398179 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0380882 |
| ADM | adrenomedullin | -0.037032 |
| RPL23 | ribosomal protein L23 | -0.0348161 |
| GNAS | GNAS complex locus | -0.0344865 |
| RPL35A | ribosomal protein L35a | -0.0335418 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330521 |
| RPL37A | ribosomal protein L37a | -0.0315045 |
| PTMA | prothymosin, alpha | -0.0311606 |
| EGR1 | early growth response 1 | -0.0296072 |
| RPL9 | ribosomal protein L9 | -0.0291015 |
| RPLP1 | ribosomal protein, large, P1 | -0.0288621 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0288293 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.028789 |
| RPL36A | ribosomal protein L36a | -0.0284673 |
| HMGA2 | high mobility group AT-hook 2 | -0.0281587 |
| GLIS3 | GLIS family zinc finger 3 | -0.0277414 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275414 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0270907 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.026984 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0269195 |
| RPLP2 | ribosomal protein, large, P2 | -0.0267705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267508 |
| RPL26 | ribosomal protein L26 | -0.0267372 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0262967 |
| B2M | beta-2-microglobulin | -0.025292 |
| TPM4 | tropomyosin 4 | -0.0251018 |
| EGFR | epidermal growth factor receptor | -0.0249673 |
| RAI14 | retinoic acid induced 14 | -0.0246825 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.024512 |
| RPS13 | ribosomal protein S13 | -0.0244664 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.0239717 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0236934 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0235777 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0234915 |
| RPS24 | ribosomal protein S24 | -0.0230524 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0229614 |
| ENO1 | enolase 1, (alpha) | -0.0229553 |
| PLIN2 | perilipin 2 | -0.0227583 |
| KRT19 | keratin 19, type I | -0.02241 |
| GDF15 | growth differentiation factor 15 | -0.0223953 |
| CLMP | CXADR-like membrane protein | -0.0219428 |
| LOX | lysyl oxidase | -0.0219408 |
| RND3 | Rho family GTPase 3 | -0.021491 |
| TMEM132D | transmembrane protein 132D | -0.0213754 |
| KPNB1 | karyopherin (importin) beta 1 | -0.021249 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0211239 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0208374 |
| RPS19 | ribosomal protein S19 | -0.0202796 |
| FRMD4A | FERM domain containing 4A | -0.0201627 |
| RPL37 | ribosomal protein L37 | -0.0201305 |
| CANX | calnexin | -0.0199751 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0199633 |
| RPL27A | ribosomal protein L27a | -0.0198159 |
| RPS27A | ribosomal protein S27a | -0.019757 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0197493 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0195976 |
| ATF4 | activating transcription factor 4 | -0.0194436 |
| CAVIN1 | caveolae associated protein 1 | -0.0191094 |
| JUN | jun proto-oncogene | -0.0190479 |
| RPL12 | ribosomal protein L12 | -0.0186447 |
| ACTG1 | actin gamma 1 | -0.0185826 |
| INHBA | inhibin, beta A | -0.018529 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0182391 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0181247 |
| RPL38 | ribosomal protein L38 | -0.0179821 |
| RACK1 | receptor for activated C kinase 1 | -0.0179261 |
| NRN1 | neuritin 1 | -0.0178853 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0177821 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0177713 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0177422 |
| RPL31 | ribosomal protein L31 | -0.0177393 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0172573 |
| RRBP1 | ribosome binding protein 1 | -0.0170658 |
| CD44 | CD44 molecule (Indian blood group) | -0.0168919 |
