| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dapagliflozin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dapagliflozin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.107686 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0744552 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.074248 |
| VIM | vimentin | 0.0719286 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0716344 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0711127 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0556972 |
| FTL | ferritin, light polypeptide | 0.0496298 |
| NDRG1 | N-myc downstream regulated 1 | 0.0479029 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0473869 |
| CD44 | CD44 molecule (Indian blood group) | 0.0461069 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460309 |
| SPAG9 | sperm associated antigen 9 | 0.0416366 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0411632 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0407762 |
| MT2A | metallothionein 2A | 0.0382212 |
| ERBIN | erbb2 interacting protein | 0.0382122 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0378361 |
| HLA-A | major histocompatibility complex, class I, A | 0.0377903 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0375869 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0373863 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336969 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0330112 |
| PKM | pyruvate kinase, muscle | 0.0329896 |
| TMEM165 | transmembrane protein 165 | 0.0325494 |
| FLNA | filamin A, alpha | 0.0318246 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0307092 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0293217 |
| PLEC | plectin | 0.0290347 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0284691 |
| CALD1 | caldesmon 1 | 0.0282296 |
| RPS8 | ribosomal protein S8 | 0.0277221 |
| SEPTIN9 | septin 9 | 0.027315 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0271933 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0271558 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0271016 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0271009 |
| WASHC4 | WASH complex subunit 4 | 0.0270682 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0268844 |
| ENO1 | enolase 1, (alpha) | 0.0267538 |
| GOLGA4 | golgin A4 | 0.0265498 |
| RTN4 | reticulon 4 | 0.026466 |
| SERINC1 | serine incorporator 1 | 0.0264079 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0260895 |
| GLG1 | golgi glycoprotein 1 | 0.0260771 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0260726 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0260626 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.025941 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0258434 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0258091 |
| HIP1 | huntingtin interacting protein 1 | 0.0257908 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0255895 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0255716 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0254683 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0253326 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0252685 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0251843 |
| TMSB10 | thymosin beta 10 | 0.025149 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0250183 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0247792 |
| SEC24D | SEC24 family member D | 0.0238491 |
| C1D | C1D nuclear receptor corepressor | 0.0238012 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0237919 |
| ARCN1 | archain 1 | 0.0236324 |
| ZNF207 | zinc finger protein 207 | 0.022859 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0227767 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0226255 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0224314 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0224053 |
| EGFR | epidermal growth factor receptor | 0.0223384 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0221677 |
| BRD2 | bromodomain containing 2 | 0.0221585 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0221468 |
| ACTN4 | actinin, alpha 4 | 0.022045 |
| RPL35A | ribosomal protein L35a | 0.0220319 |
| COG5 | component of oligomeric golgi complex 5 | 0.0220304 |
| QKI | QKI, KH domain containing, RNA binding | 0.0216865 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.0215564 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0214574 |
| RPS3 | ribosomal protein S3 | 0.0214359 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0212721 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0212497 |
| RNF24 | ring finger protein 24 | 0.0212227 |
| CADM1 | cell adhesion molecule 1 | 0.0210611 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0207152 |
| CUL4A | cullin 4A | 0.0206768 |
| ZNF654 | zinc finger protein 654 | 0.0206292 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0205738 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0204923 |
| CCDC47 | coiled-coil domain containing 47 | 0.0204367 |
| S100A9 | S100 calcium binding protein A9 | 0.0204307 |
| TMEM39A | transmembrane protein 39A | 0.0203826 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.020269 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0202439 |
| PTN | pleiotrophin | 0.0202405 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.020234 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0202191 |
| YEATS2 | YEATS domain containing 2 | 0.0202085 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0201747 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0201168 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.168231 |
| HMGA2 | high mobility group AT-hook 2 | -0.0656147 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601896 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0566447 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.052034 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0382543 |
| TNS3 | tensin 3 | -0.0372398 |
| LOX | lysyl oxidase | -0.0349488 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0342454 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0307257 |
| GLIS3 | GLIS family zinc finger 3 | -0.0301178 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0298198 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0288271 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0276472 |
| NRXN3 | neurexin 3 | -0.0274563 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0273751 |
| STC1 | stanniocalcin 1 | -0.0265664 |
| VCL | vinculin | -0.0261729 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0261228 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0254599 |
| HPCAL1 | hippocalcin-like 1 | -0.0252907 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0251141 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248292 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0239487 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0237952 |
| VEGFA | vascular endothelial growth factor A | -0.0234507 |
| RAD51B | RAD51 paralog B | -0.0233425 |
| NUCB2 | nucleobindin 2 | -0.0232134 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0231315 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0228476 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0227602 |
| MEF2A | myocyte enhancer factor 2A | -0.022422 |
| CDH13 | cadherin 13 | -0.022154 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0220947 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0220265 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0214931 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0213907 |
| TGFB1 | transforming growth factor, beta 1 | -0.0213443 |
| COL1A2 | collagen, type I, alpha 2 | -0.0211911 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0211196 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0210989 |
| ECE1 | endothelin converting enzyme 1 | -0.0210821 |
| COL5A1 | collagen, type V, alpha 1 | -0.0208582 |
| GOLM2 | golgi membrane protein 2 | -0.0207547 |
| FAM120A | family with sequence similarity 120A | -0.0206242 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0205626 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0204357 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0202458 |
| RUNX1 | runt-related transcription factor 1 | -0.0202125 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0202028 |
| JUN | jun proto-oncogene | -0.0200354 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0196997 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.0196906 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0196388 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0193124 |
| EXOC4 | exocyst complex component 4 | -0.0193088 |
| CCND1 | cyclin D1 | -0.0192602 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0190617 |
| SMYD3 | SET and MYND domain containing 3 | -0.0190073 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0190013 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0189304 |
| MT1X | metallothionein 1X | -0.0189024 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0188794 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0188453 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0187325 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0182885 |
| CCNI | cyclin I | -0.0181762 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.01805 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0179755 |
| ACTN1 | actinin, alpha 1 | -0.0179728 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0179534 |
| RPL28 | ribosomal protein L28 | -0.0179409 |
| MYO1E | myosin IE | -0.0179206 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0177559 |
| DOCK1 | dedicator of cytokinesis 1 | -0.01772 |
| NABP1 | nucleic acid binding protein 1 | -0.0175766 |
| ASPH | aspartate beta-hydroxylase | -0.0175672 |
| COPE | coatomer protein complex, subunit epsilon | -0.0174814 |
| TPR | translocated promoter region, nuclear basket protein | -0.0174185 |
| BSG | basigin (Ok blood group) | -0.0173003 |
| CEP290 | centrosomal protein 290kDa | -0.0172885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0172151 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.016892 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0168811 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0168789 |
| SMAD3 | SMAD family member 3 | -0.0168582 |
| TANK | TRAF family member-associated NFKB activator | -0.0166314 |
| SUCO | SUN domain containing ossification factor | -0.0165947 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0165552 |
| CAVIN1 | caveolae associated protein 1 | -0.0164296 |
| ANO6 | anoctamin 6 | -0.0164202 |
| CMIP | c-Maf inducing protein | -0.0163132 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.016255 |
| WWOX | WW domain containing oxidoreductase | -0.0161028 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0160514 |
| DENND4C | DENN/MADD domain containing 4C | -0.0160512 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0160141 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0159919 |
| S100A10 | S100 calcium binding protein A10 | -0.0159546 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0159357 |
