Dapiprazole Gene Set

Dataset DeepCoverMOA Drug Mechanisms of Action
Category proteomics
Type drug perturbation
External Link https://pubchem.ncbi.nlm.nih.gov/compound/3033538
Similar Terms
Downloads & Tools

Genes

198 proteins with high or low expression in Dapiprazole relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

high expression

Symbol Name Standardized Value
ZNF160 zinc finger protein 160 0.79
FN1 fibronectin 1 0.66
CORO1A coronin, actin binding protein, 1A 0.51
TSLIG1 tRNA splicing ligase complex subunit 1 0.47
CELF1 CUGBP, Elav-like family member 1 0.47
VIM vimentin 0.46
DCLRE1A DNA cross-link repair 1A 0.45
ENO1 enolase 1, (alpha) 0.44
HES1 hes family bHLH transcription factor 1 0.44
MSH5 mutS homolog 5 0.43
STARD4 StAR-related lipid transfer (START) domain containing 4 0.42
DDN dendrin 0.42
IFFO2 intermediate filament family orphan 2 0.42
SYT17 synaptotagmin XVII 0.4
ZNRD1 zinc ribbon domain containing 1 0.4
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.39
NOTCH3 notch 3 0.39
ZNF696 zinc finger protein 696 0.38
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 0.38
MBOAT1 membrane bound O-acyltransferase domain containing 1 0.37
ICOSLG inducible T-cell co-stimulator ligand 0.36
RAB27B RAB27B, member RAS oncogene family 0.35
CRTC3 CREB regulated transcription coactivator 3 0.35
HINFP histone H4 transcription factor 0.34
CCND3 cyclin D3 0.34
TSPAN9 tetraspanin 9 0.34
EVA1C eva-1 homolog C (C. elegans) 0.34
DEPDC7 DEP domain containing 7 0.33
NCKAP5L NCK-associated protein 5-like 0.33
COL13A1 collagen, type XIII, alpha 1 0.33
CTTN cortactin 0.33
ZNF652 zinc finger protein 652 0.33
DCAF10 DDB1 and CUL4 associated factor 10 0.32
DESI2 desumoylating isopeptidase 2 0.32
KRT8 keratin 8, type II 0.32
HIPK1 homeodomain interacting protein kinase 1 0.32
C12ORF57 chromosome 12 open reading frame 57 0.32
SOX7 SRY (sex determining region Y)-box 7 0.32
CCP110 centriolar coiled coil protein 110kDa 0.31
ATXN7L3B ataxin 7-like 3B 0.31
CA8 carbonic anhydrase VIII 0.31
KLHL29 kelch-like family member 29 0.31
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.3
YAE1 YAE1 maturation factor of ABCE1 0.3
ACSL6 acyl-CoA synthetase long-chain family member 6 0.3
PWWP2B PWWP domain containing 2B 0.29
VAMP3 vesicle-associated membrane protein 3 0.29
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 0.29
MLF1 myeloid leukemia factor 1 0.29
RTN4RL2 reticulon 4 receptor-like 2 0.28
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.28
AXIN1 axin 1 0.28
SPDL1 spindle apparatus coiled-coil protein 1 0.27
FGF19 fibroblast growth factor 19 0.27
ZNF618 zinc finger protein 618 0.27
CDKN3 cyclin-dependent kinase inhibitor 3 0.27
FGFR1OP2 FGFR1 oncogene partner 2 0.27
ZIC2 Zic family member 2 0.27
RXYLT1 ribitol xylosyltransferase 1 0.27
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.27
UNC13A unc-13 homolog A (C. elegans) 0.27
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.26
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 0.25
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.25
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.25
MEX3C mex-3 RNA binding family member C 0.25
CMC1 C-x(9)-C motif containing 1 0.25
NFE2L2 nuclear factor, erythroid 2-like 2 0.25
GLRX glutaredoxin (thioltransferase) 0.25
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.25
CDC25A cell division cycle 25A 0.25
S100A5 S100 calcium binding protein A5 0.25
ZNF516 zinc finger protein 516 0.24
PANK1 pantothenate kinase 1 0.24
KLHDC3 kelch domain containing 3 0.24
BTG3 BTG family, member 3 0.24
SYK spleen tyrosine kinase 0.24
CDCA4 cell division cycle associated 4 0.24
HIPK3 homeodomain interacting protein kinase 3 0.24
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.24
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.24
TMEM177 transmembrane protein 177 0.24
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 0.24
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.24
ODF2L outer dense fiber of sperm tails 2-like 0.24
ARL16 ADP-ribosylation factor-like 16 0.24
TM7SF3 transmembrane 7 superfamily member 3 0.24
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.23
NECTIN3 nectin cell adhesion molecule 3 0.23
SPTB spectrin, beta, erythrocytic 0.23
RGS19 regulator of G-protein signaling 19 0.23
ATG4D autophagy related 4D, cysteine peptidase 0.23
CECR2 cat eye syndrome chromosome region, candidate 2 0.23
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.23
SLC22A23 solute carrier family 22, member 23 0.23
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.23
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.23
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.23
ABLIM3 actin binding LIM protein family, member 3 0.22

low expression

Symbol Name Standardized Value
NALCN sodium leak channel, non selective -4.42
ALPK3 alpha-kinase 3 -2.38
SEPTIN4 septin 4 -1.81
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -1.26
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -1.23
SMC1B structural maintenance of chromosomes 1B -1.11
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -0.93
SUMO1 small ubiquitin-like modifier 1 -0.73
TMEM175 transmembrane protein 175 -0.61
XIRP1 xin actin binding repeat containing 1 -0.58
RPL26 ribosomal protein L26 -0.56
TBX3 T-box 3 -0.54
CKM creatine kinase, muscle -0.51
PIP prolactin-induced protein -0.49
RNF4 ring finger protein 4 -0.47
SET SET nuclear proto-oncogene -0.47
CAV2 caveolin 2 -0.47
KIAA1210 KIAA1210 -0.45
LRP10 low density lipoprotein receptor-related protein 10 -0.45
EPHA4 EPH receptor A4 -0.42
PCTP phosphatidylcholine transfer protein -0.4
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.38
LMBR1 limb development membrane protein 1 -0.38
JAGN1 jagunal homolog 1 (Drosophila) -0.38
DNAH9 dynein, axonemal, heavy chain 9 -0.36
ASB8 ankyrin repeat and SOCS box containing 8 -0.36
ARG2 arginase 2 -0.36
MT-CO1 cytochrome c oxidase subunit I -0.34
PAQR7 progestin and adipoQ receptor family member VII -0.34
SOCS2 suppressor of cytokine signaling 2 -0.34
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.34
ATP9A ATPase, class II, type 9A -0.33
HIPK2 homeodomain interacting protein kinase 2 -0.33
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -0.33
PEX7 peroxisomal biogenesis factor 7 -0.31
ZNF175 zinc finger protein 175 -0.31
TRIM38 tripartite motif containing 38 -0.31
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -0.3
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.3
ATP5IF1 ATP synthase inhibitory factor subunit 1 -0.3
DTX2 deltex 2, E3 ubiquitin ligase -0.3
OPTN optineurin -0.29
YBX3 Y box binding protein 3 -0.29
ZDHHC23 zinc finger, DHHC-type containing 23 -0.29
SS18 synovial sarcoma translocation, chromosome 18 -0.29
ZNF729 zinc finger protein 729 -0.29
BRD7 bromodomain containing 7 -0.28
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.27
RNF146 ring finger protein 146 -0.27
FJX1 four jointed box 1 (Drosophila) -0.26
BCO2 beta-carotene oxygenase 2 -0.26
MFSD6 major facilitator superfamily domain containing 6 -0.26
TTC9 tetratricopeptide repeat domain 9 -0.25
SEC23A Sec23 homolog A (S. cerevisiae) -0.25
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -0.25
TST thiosulfate sulfurtransferase (rhodanese) -0.24
CEP57 centrosomal protein 57kDa -0.24
PKM pyruvate kinase, muscle -0.24
RPL29 ribosomal protein L29 -0.24
KLK7 kallikrein-related peptidase 7 -0.24
RHOD ras homolog family member D -0.23
SVIP small VCP/p97-interacting protein -0.23
TIMP3 TIMP metallopeptidase inhibitor 3 -0.23
TMED2 transmembrane emp24 domain trafficking protein 2 -0.23
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -0.23
RPL18A ribosomal protein L18a -0.23
ICAM1 intercellular adhesion molecule 1 -0.23
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -0.23
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -0.23
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.22
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -0.22
PECR peroxisomal trans-2-enoyl-CoA reductase -0.22
CASZ1 castor zinc finger 1 -0.22
MOB1B MOB kinase activator 1B -0.22
ZNRD2 zinc ribbon domain containing 2 -0.22
ACTA1 actin, alpha 1, skeletal muscle -0.22
ZDHHC9 zinc finger, DHHC-type containing 9 -0.22
TMEM59 transmembrane protein 59 -0.22
RPL31 ribosomal protein L31 -0.22
CD274 CD274 molecule -0.22
CHRD chordin -0.22
MYH9 myosin, heavy chain 9, non-muscle -0.21
TRIM68 tripartite motif containing 68 -0.21
AARSD1 alanyl-tRNA synthetase domain containing 1 -0.21
STK16 serine/threonine kinase 16 -0.21
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.21
SIDT2 SID1 transmembrane family, member 2 -0.21
LETMD1 LETM1 domain containing 1 -0.21
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.2
PCNP PEST proteolytic signal containing nuclear protein -0.2
RAB26 RAB26, member RAS oncogene family -0.2
UST uronyl-2-sulfotransferase -0.2
GEM GTP binding protein overexpressed in skeletal muscle -0.2
PDIA3 protein disulfide isomerase family A, member 3 -0.2
HINT2 histidine triad nucleotide binding protein 2 -0.2
CYBA cytochrome b-245, alpha polypeptide -0.2
GGT2 gamma-glutamyltransferase 2 -0.2
TACSTD2 tumor-associated calcium signal transducer 2 -0.2
EZR ezrin -0.2