Dapsone Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. (Chemical Entities of Biological Interest Ontology, CHEBI_4325)
External Link http://www.drugbank.ca/drugs/DB00250
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Genes

13 interacting proteins for the Dapsone drug from the curated DrugBank Drug Targets dataset.

Symbol Name
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
FMO3 flavin containing monooxygenase 3
MPO myeloperoxidase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)