| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daptomycin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.250045 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.186963 |
| DST | dystonin | 0.141585 |
| DPYD | dihydropyrimidine dehydrogenase | 0.124101 |
| ANXA1 | annexin A1 | 0.115568 |
| AREG | amphiregulin | 0.107024 |
| TXNRD1 | thioredoxin reductase 1 | 0.101687 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.100611 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0995399 |
| CLDN1 | claudin 1 | 0.0956585 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.095199 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0950259 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0871745 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0848876 |
| CCN2 | cellular communication network factor 2 | 0.0766092 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0760537 |
| NLGN1 | neuroligin 1 | 0.0736119 |
| PLK2 | polo-like kinase 2 | 0.0696958 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0696678 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0692278 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0681693 |
| RASAL2 | RAS protein activator like 2 | 0.0668848 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0643335 |
| EDN1 | endothelin 1 | 0.0632224 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.062447 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0618929 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0617852 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0588588 |
| DTNA | dystrobrevin, alpha | 0.0586342 |
| CALD1 | caldesmon 1 | 0.0577651 |
| EZR | ezrin | 0.0571822 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0556322 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0546938 |
| YBX3 | Y box binding protein 3 | 0.0546327 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0534378 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0506873 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0490243 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0486453 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.046411 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0460962 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0457265 |
| EGFR | epidermal growth factor receptor | 0.0450926 |
| PCDH7 | protocadherin 7 | 0.0440901 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0440736 |
| MKI67 | marker of proliferation Ki-67 | 0.0438619 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0435833 |
| TPM3 | tropomyosin 3 | 0.0413267 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0407158 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0404056 |
| RTN4 | reticulon 4 | 0.0400546 |
| CCNL1 | cyclin L1 | 0.0395701 |
| UBC | ubiquitin C | 0.0387633 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383985 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0372017 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0370569 |
| PRR16 | proline rich 16 | 0.0369291 |
| SPAG9 | sperm associated antigen 9 | 0.0368945 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0367379 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0366288 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0363359 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0359313 |
| ERBIN | erbb2 interacting protein | 0.035095 |
| SBF2 | SET binding factor 2 | 0.0343497 |
| RPL3 | ribosomal protein L3 | 0.033914 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0338996 |
| KLC1 | kinesin light chain 1 | 0.0331071 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0312613 |
| NEGR1 | neuronal growth regulator 1 | 0.0312442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0298015 |
| ACTG1 | actin gamma 1 | 0.0297853 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0291932 |
| MGAT4C | MGAT4 family, member C | 0.0290658 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0290201 |
| KIF5B | kinesin family member 5B | 0.0289991 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0287058 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284087 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0281911 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0280004 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0279313 |
| DSPP | dentin sialophosphoprotein | 0.027303 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0270872 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0268483 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.026826 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0267084 |
| LMO7 | LIM domain 7 | 0.026428 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0262318 |
| CEP192 | centrosomal protein 192kDa | 0.0260598 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0260593 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0258695 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0257088 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0255154 |
| XPOT | exportin, tRNA | 0.025478 |
| ZNF804A | zinc finger protein 804A | 0.0252877 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251387 |
| KIF1B | kinesin family member 1B | 0.0250356 |
| MYPN | myopalladin | 0.0246861 |
| HDGF | hepatoma-derived growth factor | 0.0246403 |
| FMNL2 | formin-like 2 | 0.0242266 |
| MAP1B | microtubule-associated protein 1B | 0.0241444 |
| EXOC6B | exocyst complex component 6B | 0.0240048 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.116866 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0952032 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0701805 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0663614 |
| RPL35A | ribosomal protein L35a | -0.0630617 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547692 |
| NHSL1 | NHS-like 1 | -0.0517989 |
| LDHA | lactate dehydrogenase A | -0.0514794 |
| HMGA1 | high mobility group AT-hook 1 | -0.0459851 |
| EGR1 | early growth response 1 | -0.0430234 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0429812 |
| TUBA1B | tubulin, alpha 1b | -0.0421068 |
| HMGA2 | high mobility group AT-hook 2 | -0.0414138 |
| FTL | ferritin, light polypeptide | -0.0410816 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0408457 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0404691 |
| YAP1 | Yes-associated protein 1 | -0.0396997 |
| TUBB | tubulin, beta class I | -0.0361697 |
| RRM2 | ribonucleotide reductase M2 | -0.0346601 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0343078 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0329178 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318854 |
| RPS21 | ribosomal protein S21 | -0.0315415 |
| PGK1 | phosphoglycerate kinase 1 | -0.0301029 |
| EDARADD | EDAR-associated death domain | -0.0300552 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0288609 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0288485 |
| RPS20 | ribosomal protein S20 | -0.0287825 |
| PTMA | prothymosin, alpha | -0.0286873 |
| RPS24 | ribosomal protein S24 | -0.0280032 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.027592 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0270951 |
| EHBP1 | EH domain binding protein 1 | -0.0270099 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266541 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0263598 |
| HMGB1 | high mobility group box 1 | -0.0262491 |
| ZNF638 | zinc finger protein 638 | -0.0261145 |
| ADIPOR2 | adiponectin receptor 2 | -0.0258673 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.02569 |
| RAD51B | RAD51 paralog B | -0.0255874 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0253887 |
| CDK17 | cyclin-dependent kinase 17 | -0.0250581 |
| USP34 | ubiquitin specific peptidase 34 | -0.0243883 |
| MMP12 | matrix metallopeptidase 12 | -0.0239753 |
| INTS6 | integrator complex subunit 6 | -0.0233086 |
| RPS29 | ribosomal protein S29 | -0.0232094 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0226541 |
| RPS23 | ribosomal protein S23 | -0.0226299 |
| RPLP0 | ribosomal protein, large, P0 | -0.0221428 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0219877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0218026 |
| RPL7 | ribosomal protein L7 | -0.0213746 |
| MED13 | mediator complex subunit 13 | -0.0209448 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0206509 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0205997 |
| RPL34 | ribosomal protein L34 | -0.0205772 |
| RPS8 | ribosomal protein S8 | -0.0204719 |
| SMYD3 | SET and MYND domain containing 3 | -0.0203415 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0200321 |
| SQSTM1 | sequestosome 1 | -0.0196166 |
| RPL26 | ribosomal protein L26 | -0.0194895 |
| WWOX | WW domain containing oxidoreductase | -0.0194394 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0193219 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0193067 |
| PEG10 | paternally expressed 10 | -0.0192177 |
| RPS19 | ribosomal protein S19 | -0.019015 |
| RPL36 | ribosomal protein L36 | -0.0188986 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0188923 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0184841 |
| RTN3 | reticulon 3 | -0.0183152 |
| GCG | glucagon | -0.0182707 |
| ZNF217 | zinc finger protein 217 | -0.0180655 |
| VCL | vinculin | -0.0178924 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0178235 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0174615 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0174365 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0173783 |
| HELLS | helicase, lymphoid-specific | -0.0172852 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0171488 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0170885 |
| DEK | DEK proto-oncogene | -0.0168597 |
| KLHL24 | kelch-like family member 24 | -0.0165475 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0164545 |
| ETV6 | ets variant 6 | -0.0163411 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0162783 |
| RPS16 | ribosomal protein S16 | -0.0162614 |
| TMEM41B | transmembrane protein 41B | -0.0162504 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0162284 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0159528 |
| POU2F1 | POU class 2 homeobox 1 | -0.0158929 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0158902 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0157849 |
| NEBL | nebulette | -0.0157739 |
| FGF20 | fibroblast growth factor 20 | -0.0156024 |
| RPL9 | ribosomal protein L9 | -0.0154644 |
| YBX1 | Y box binding protein 1 | -0.0153495 |
| FAF2 | Fas associated factor family member 2 | -0.015299 |
| TMEM123 | transmembrane protein 123 | -0.0152414 |
| RPS13 | ribosomal protein S13 | -0.0152058 |
| H3-3B | H3.3 histone B | -0.0152021 |
