| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCKAP5 | NCK-associated protein 5 | 0.145456 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.106064 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0833645 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0822725 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0557129 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0512622 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.049157 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0481545 |
| DST | dystonin | 0.0474655 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0453514 |
| H1-0 | H1.0 linker histone | 0.0417506 |
| CANX | calnexin | 0.0404688 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0387254 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0372182 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0355527 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0349381 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.034301 |
| RNF43 | ring finger protein 43 | 0.0342075 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0337862 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0331098 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0329717 |
| USP54 | ubiquitin specific peptidase 54 | 0.0320059 |
| DUSP16 | dual specificity phosphatase 16 | 0.0315419 |
| MKI67 | marker of proliferation Ki-67 | 0.0314249 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0313463 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.030683 |
| UBC | ubiquitin C | 0.0302479 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0296199 |
| IFNGR1 | interferon gamma receptor 1 | 0.0293694 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0292895 |
| MUC20 | mucin 20, cell surface associated | 0.0287543 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0282855 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0274659 |
| ARRDC3 | arrestin domain containing 3 | 0.0270654 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0270301 |
| TNNC1 | troponin C type 1 (slow) | 0.0269979 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0268952 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.026693 |
| OGA | O-GlcNAcase | 0.0264424 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0263468 |
| STEAP2 | STEAP family member 2, metalloreductase | 0.0259171 |
| ATP10B | ATPase, class V, type 10B | 0.0251781 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0250814 |
| CALR | calreticulin | 0.024994 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.024827 |
| RUNX1 | runt-related transcription factor 1 | 0.0244385 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0242751 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0241599 |
| POF1B | premature ovarian failure, 1B | 0.0241574 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0239827 |
| PRELID2 | PRELI domain containing 2 | 0.0239515 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0239049 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0238477 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0238051 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0234462 |
| AHNAK | AHNAK nucleoprotein | 0.023186 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0231041 |
| EHF | ets homologous factor | 0.023004 |
| JMJD1C | jumonji domain containing 1C | 0.0227721 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0226921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0225654 |
| KIAA1217 | KIAA1217 | 0.022324 |
| CENPF | centromere protein F, 350/400kDa | 0.022179 |
| MECOM | MDS1 and EVI1 complex locus | 0.0221011 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0220861 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0217217 |
| TC2N | tandem C2 domains, nuclear | 0.0212979 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0212749 |
| ATXN1 | ataxin 1 | 0.0212419 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0211402 |
| NCALD | neurocalcin delta | 0.0210501 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.020463 |
| FAAH2 | fatty acid amide hydrolase 2 | 0.0203817 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0201846 |
| APP | amyloid beta (A4) precursor protein | 0.02013 |
| ITGB6 | integrin, beta 6 | 0.0198693 |
| RTN4 | reticulon 4 | 0.0197892 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0197466 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0197397 |
| CD44 | CD44 molecule (Indian blood group) | 0.0196396 |
| PHF3 | PHD finger protein 3 | 0.0194848 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0191984 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0191886 |
| IFT88 | intraflagellar transport 88 | 0.0191827 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0191742 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.0187468 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0187266 |
| ATM | ATM serine/threonine kinase | 0.0187201 |
| LIPH | lipase, member H | 0.0187128 |
| ALPK1 | alpha-kinase 1 | 0.0186083 |
| PRSS3 | protease, serine, 3 | 0.0184899 |
| IL20RA | interleukin 20 receptor, alpha | 0.0182873 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.018194 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0181827 |
| PDZD8 | PDZ domain containing 8 | 0.0181032 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0180991 |
| ASPH | aspartate beta-hydroxylase | 0.0180138 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.0178158 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0177747 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0177521 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.16216 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.125134 |
| ERBIN | erbb2 interacting protein | -0.123222 |
| EGR1 | early growth response 1 | -0.0986219 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0956832 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0944289 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0901547 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0876205 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.077672 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0722585 |
| LYZ | lysozyme | -0.0722211 |
| PTMA | prothymosin, alpha | -0.068236 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0660537 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0633293 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0616555 |
| PKM | pyruvate kinase, muscle | -0.0603924 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.060272 |
| NPSR1 | neuropeptide S receptor 1 | -0.0600249 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0598964 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0596558 |
| AREG | amphiregulin | -0.0587364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0583665 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0570259 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0565449 |
| RNF213 | ring finger protein 213 | -0.0560868 |
| FTL | ferritin, light polypeptide | -0.0552766 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0544806 |
| RPL35A | ribosomal protein L35a | -0.054316 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0500414 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0479707 |
| TJP1 | tight junction protein 1 | -0.0479482 |
| MAP7 | microtubule-associated protein 7 | -0.0466477 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046383 |
| MX2 | MX dynamin-like GTPase 2 | -0.0455825 |
| HLA-B | major histocompatibility complex, class I, B | -0.0446357 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0433697 |
| MT2A | metallothionein 2A | -0.0432872 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0422384 |
| ITGA6 | integrin, alpha 6 | -0.0421906 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0420482 |
| DIAPH1 | diaphanous-related formin 1 | -0.0419913 |
| POTEF | POTE ankyrin domain family, member F | -0.0416175 |
| LOC112694756 | uncharaterized LOC112694756 | -0.040505 |
| TMSB10 | thymosin beta 10 | -0.0398622 |
| TMC5 | transmembrane channel-like 5 | -0.0393853 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0389256 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0372813 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0369255 |
| RIGI | RNA sensor RIG-I | -0.036776 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0367356 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0350273 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0349786 |
| BCL2L1 | BCL2-like 1 | -0.0346876 |
| TNS4 | tensin 4 | -0.0342715 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0341286 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340382 |
| RPLP1 | ribosomal protein, large, P1 | -0.0335344 |
| HM13 | histocompatibility (minor) 13 | -0.033331 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0329788 |
| UBAP2 | ubiquitin associated protein 2 | -0.0329782 |
| RPL34 | ribosomal protein L34 | -0.0327549 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0324481 |
| MSI2 | musashi RNA-binding protein 2 | -0.0321504 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0321481 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0321421 |
| KRT19 | keratin 19, type I | -0.0319878 |
| RPL23 | ribosomal protein L23 | -0.0314991 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.031084 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.03099 |
| ACTG1 | actin gamma 1 | -0.0307425 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0302187 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.029939 |
| S100P | S100 calcium binding protein P | -0.0296547 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0291503 |
| ATF4 | activating transcription factor 4 | -0.0290539 |
| RPS6 | ribosomal protein S6 | -0.0290446 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0282386 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0281825 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0281191 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0279989 |
| EFHD2 | EF-hand domain family, member D2 | -0.027245 |
| HLA-A | major histocompatibility complex, class I, A | -0.0268225 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.026819 |
| CTSD | cathepsin D | -0.02675 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0267207 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0266927 |
| SERINC5 | serine incorporator 5 | -0.0266225 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0265655 |
| INTS6 | integrator complex subunit 6 | -0.0265486 |
| SP100 | SP100 nuclear antigen | -0.0264819 |
| RPS8 | ribosomal protein S8 | -0.0264403 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0263277 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0262529 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0262377 |
| MCL1 | myeloid cell leukemia 1 | -0.026158 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259944 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0259229 |
| RPS24 | ribosomal protein S24 | -0.0257942 |
| TOB1 | transducer of ERBB2, 1 | -0.0257325 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0254503 |
