| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.24796 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.221587 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.174312 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.155558 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.153652 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.150081 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.112411 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108575 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.103541 |
| ATP13A3 | ATPase type 13A3 | 0.0902503 |
| TPM4 | tropomyosin 4 | 0.0896158 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0876031 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0838294 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0825796 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0812408 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0793377 |
| FN1 | fibronectin 1 | 0.0670648 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0667503 |
| CALD1 | caldesmon 1 | 0.066326 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0660758 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0653535 |
| CADM1 | cell adhesion molecule 1 | 0.0623156 |
| CALR | calreticulin | 0.0593739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0531065 |
| GOLGA4 | golgin A4 | 0.0531036 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0527546 |
| CDH13 | cadherin 13 | 0.0516609 |
| FLNA | filamin A, alpha | 0.0500498 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0491404 |
| ADM | adrenomedullin | 0.0490258 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0440606 |
| FMNL2 | formin-like 2 | 0.0423091 |
| LOX | lysyl oxidase | 0.0410208 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0407909 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0403834 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0399943 |
| INHBA | inhibin, beta A | 0.0399708 |
| NAV2 | neuron navigator 2 | 0.0395029 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0383742 |
| DST | dystonin | 0.0352453 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0347423 |
| ZNF292 | zinc finger protein 292 | 0.0345523 |
| UBC | ubiquitin C | 0.0332813 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0327152 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0325531 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0323797 |
| RASA2 | RAS p21 protein activator 2 | 0.0321432 |
| PRELID2 | PRELI domain containing 2 | 0.0317974 |
| CALU | calumenin | 0.0314268 |
| PTK2 | protein tyrosine kinase 2 | 0.0310765 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0310014 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0308513 |
| CCNL1 | cyclin L1 | 0.030658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300621 |
| MYO10 | myosin X | 0.0296019 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.029316 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0289824 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0289677 |
| SPAG9 | sperm associated antigen 9 | 0.0287234 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0284293 |
| HYOU1 | hypoxia up-regulated 1 | 0.0278695 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0278636 |
| RPS6 | ribosomal protein S6 | 0.0275078 |
| QKI | QKI, KH domain containing, RNA binding | 0.0274435 |
| COG5 | component of oligomeric golgi complex 5 | 0.0266508 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.026165 |
| PLEC | plectin | 0.0255498 |
| RUNX1 | runt-related transcription factor 1 | 0.0254864 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.024881 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0248196 |
| MRTFA | myocardin related transcription factor A | 0.0246786 |
| OGA | O-GlcNAcase | 0.0246698 |
| ACTG1 | actin gamma 1 | 0.0246306 |
| RPL3 | ribosomal protein L3 | 0.0244939 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0244582 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0236091 |
| SLTM | SAFB-like, transcription modulator | 0.0233652 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0227596 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0225193 |
| CLINT1 | clathrin interactor 1 | 0.0224874 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0224843 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0223378 |
| TFG | TRK-fused gene | 0.0222897 |
| CANX | calnexin | 0.0221211 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0217995 |
| PDE8A | phosphodiesterase 8A | 0.0216081 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0214428 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0213997 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0212313 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0211275 |
| FLNB | filamin B, beta | 0.0206516 |
| HELZ | helicase with zinc finger | 0.0203032 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0201025 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0200742 |
| USP3 | ubiquitin specific peptidase 3 | 0.020058 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0199226 |
| MYO1B | myosin IB | 0.0196747 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0196618 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0196344 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0196116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241251 |
| COL1A1 | collagen, type I, alpha 1 | -0.174122 |
| MT2A | metallothionein 2A | -0.156082 |
| CD44 | CD44 molecule (Indian blood group) | -0.141072 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.131075 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.119074 |
| VIM | vimentin | -0.115034 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.108201 |
| TMSB10 | thymosin beta 10 | -0.0970458 |
| LDHA | lactate dehydrogenase A | -0.0930525 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0847746 |
| GLIS3 | GLIS family zinc finger 3 | -0.074037 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0608604 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0590167 |
| SDC2 | syndecan 2 | -0.0568279 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0552773 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0542191 |
| ECE1 | endothelin converting enzyme 1 | -0.0511155 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0502149 |
| NDRG1 | N-myc downstream regulated 1 | -0.0498037 |
| EGR1 | early growth response 1 | -0.0492554 |
| HLA-B | major histocompatibility complex, class I, B | -0.0474492 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0470348 |
| FTL | ferritin, light polypeptide | -0.046206 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0449811 |
| ASPH | aspartate beta-hydroxylase | -0.042714 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0414657 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0393164 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0373949 |
| RPL35A | ribosomal protein L35a | -0.0373792 |
| HAS2 | hyaluronan synthase 2 | -0.0372938 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.037091 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.03695 |
| FBN1 | fibrillin 1 | -0.0365894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0348282 |
| NRP1 | neuropilin 1 | -0.0343752 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0333138 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0331297 |
| TUBB | tubulin, beta class I | -0.0330854 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0325814 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0321955 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0321903 |
| HMGA2 | high mobility group AT-hook 2 | -0.0318403 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0310781 |
| MTSS1 | metastasis suppressor 1 | -0.0306736 |
| TUBA1B | tubulin, alpha 1b | -0.0300942 |
| RIGI | RNA sensor RIG-I | -0.0297495 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296377 |
| PALLD | palladin, cytoskeletal associated protein | -0.0295521 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.02836 |
| MYADM | myeloid-associated differentiation marker | -0.0280985 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0279361 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0276023 |
| MT1X | metallothionein 1X | -0.0275457 |
| CPQ | carboxypeptidase Q | -0.0275436 |
| HMGA1 | high mobility group AT-hook 1 | -0.0268719 |
| NAV1 | neuron navigator 1 | -0.0267933 |
| SMAD3 | SMAD family member 3 | -0.0267303 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0265816 |
| DUSP6 | dual specificity phosphatase 6 | -0.0257279 |
| FAM20C | family with sequence similarity 20, member C | -0.0257163 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0254792 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0254075 |
| EBF1 | early B-cell factor 1 | -0.0253659 |
| TAPBP | TAP binding protein (tapasin) | -0.0250601 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0250338 |
| LOXL2 | lysyl oxidase-like 2 | -0.0247901 |
| B2M | beta-2-microglobulin | -0.0247394 |
| JAG1 | jagged 1 | -0.0245668 |
| HLA-A | major histocompatibility complex, class I, A | -0.0243786 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0243595 |
| NREP | neuronal regeneration related protein | -0.0243273 |
| JAK2 | Janus kinase 2 | -0.0235499 |
| MX2 | MX dynamin-like GTPase 2 | -0.0233867 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0231922 |
| TAGLN2 | transgelin 2 | -0.0228673 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0222821 |
| VCL | vinculin | -0.0218898 |
| SVIL | supervillin | -0.0217437 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.021703 |
| ANTXR2 | anthrax toxin receptor 2 | -0.02144 |
| PKM | pyruvate kinase, muscle | -0.021362 |
| VEGFA | vascular endothelial growth factor A | -0.0213124 |
| RPLP1 | ribosomal protein, large, P1 | -0.021305 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0209922 |
| S100A6 | S100 calcium binding protein A6 | -0.0203766 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0202506 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0200336 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0199447 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0199253 |
| AOPEP | aminopeptidase O (putative) | -0.0198383 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0197203 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0194326 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0193887 |
| PGK1 | phosphoglycerate kinase 1 | -0.0191504 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0187686 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0186374 |
| ANXA2 | annexin A2 | -0.0186224 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.018363 |
| RPL36 | ribosomal protein L36 | -0.018223 |
