| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | 0.188443 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.183455 |
| C3 | complement component 3 | 0.103431 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0940245 |
| FN1 | fibronectin 1 | 0.0881967 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0654006 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0566403 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0542525 |
| DSPP | dentin sialophosphoprotein | 0.0445851 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0395631 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0391337 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0387621 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0372126 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0351612 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0346876 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0345664 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303947 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.029145 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0289915 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0282676 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0270709 |
| PEG3 | paternally expressed 3 | 0.0263603 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0262398 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0254127 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0253765 |
| RPS6 | ribosomal protein S6 | 0.0237938 |
| TRIM26 | tripartite motif containing 26 | 0.0235748 |
| PRELID2 | PRELI domain containing 2 | 0.0232742 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0229204 |
| SVIL | supervillin | 0.0227156 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0219169 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0216115 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0214281 |
| CFB | complement factor B | 0.0214042 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0210564 |
| UBC | ubiquitin C | 0.0204353 |
| RPS12 | ribosomal protein S12 | 0.0200974 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0198813 |
| YAP1 | Yes-associated protein 1 | 0.0191156 |
| NFIA | nuclear factor I/A | 0.0190819 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.018861 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0185195 |
| MKI67 | marker of proliferation Ki-67 | 0.0183756 |
| ITGA1 | integrin, alpha 1 | 0.0182822 |
| CRLS1 | cardiolipin synthase 1 | 0.0180543 |
| OSMR | oncostatin M receptor | 0.0179959 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0177267 |
| DOCK5 | dedicator of cytokinesis 5 | 0.017634 |
| GOLGA4 | golgin A4 | 0.0171635 |
| ZNF292 | zinc finger protein 292 | 0.0169692 |
| WWC2 | WW and C2 domain containing 2 | 0.0169621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0166329 |
| RPL3 | ribosomal protein L3 | 0.0161872 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.0161855 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0159238 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0155025 |
| PTK2 | protein tyrosine kinase 2 | 0.0154517 |
| PTMA | prothymosin, alpha | 0.015319 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0152941 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0149931 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0145718 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0144501 |
| RRBP1 | ribosome binding protein 1 | 0.0144327 |
| HLF | hepatic leukemia factor | 0.0143607 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0143022 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0141168 |
| OGA | O-GlcNAcase | 0.0138862 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0138631 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0138199 |
| PKP4 | plakophilin 4 | 0.0137961 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.013647 |
| FAT1 | FAT atypical cadherin 1 | 0.0134951 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0132247 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0131217 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0128326 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0128271 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0127349 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.012718 |
| FHIT | fragile histidine triad | 0.0125041 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0124945 |
| FBXO11 | F-box protein 11 | 0.0124623 |
| CFDP1 | craniofacial development protein 1 | 0.0124023 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.0122978 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0122953 |
| CCNL1 | cyclin L1 | 0.0122648 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0122076 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0120092 |
| PCM1 | pericentriolar material 1 | 0.0120087 |
| ALPK2 | alpha-kinase 2 | 0.0119278 |
| BPTF | bromodomain PHD finger transcription factor | 0.0118939 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0118362 |
| LAMB1 | laminin, beta 1 | 0.0118123 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0117468 |
| NCKAP1 | NCK-associated protein 1 | 0.0116432 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0115818 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0114907 |
| CALR | calreticulin | 0.0114413 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0113557 |
| TXNRD1 | thioredoxin reductase 1 | 0.0113508 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0113207 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.505665 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.196615 |
| AHSG | alpha-2-HS-glycoprotein | -0.0504585 |
| GPC6 | glypican 6 | -0.0424798 |
| HMGA1 | high mobility group AT-hook 1 | -0.03888 |
| ASPH | aspartate beta-hydroxylase | -0.0373262 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.037155 |
| GK | glycerol kinase | -0.0349207 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0333908 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0323452 |
| SDC4 | syndecan 4 | -0.0310811 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0294135 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0288617 |
| CP | ceruloplasmin (ferroxidase) | -0.0273783 |
| PLIN2 | perilipin 2 | -0.0257607 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0253625 |
| INTS6 | integrator complex subunit 6 | -0.0245573 |
| APOA2 | apolipoprotein A-II | -0.0233392 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0227843 |
| RPL35A | ribosomal protein L35a | -0.0225252 |
| RPS24 | ribosomal protein S24 | -0.0223574 |
| TMSB10 | thymosin beta 10 | -0.0219095 |
| FAM107B | family with sequence similarity 107, member B | -0.0219052 |
| EGR1 | early growth response 1 | -0.021339 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0209661 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0207841 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0204892 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0201053 |
| PERP | PERP, TP53 apoptosis effector | -0.0195533 |
| DTNA | dystrobrevin, alpha | -0.019527 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0191171 |
| ATXN1 | ataxin 1 | -0.0187356 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0186976 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0175627 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0173897 |
| NPR2 | natriuretic peptide receptor 2 | -0.0172684 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0171821 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0166984 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0165119 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0162967 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.016288 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0161229 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0160304 |
| GPC3 | glypican 3 | -0.0147897 |
| LDHA | lactate dehydrogenase A | -0.0146768 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0145999 |
| LYZ | lysozyme | -0.0145775 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.014383 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0142076 |
| SQSTM1 | sequestosome 1 | -0.0140512 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0139197 |
| TMEM123 | transmembrane protein 123 | -0.0137094 |
| PARD3 | par-3 family cell polarity regulator | -0.0136277 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0135408 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0134517 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0134397 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0133065 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0131463 |
| FLNB | filamin B, beta | -0.012992 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0128416 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0125743 |
| TPM4 | tropomyosin 4 | -0.0125722 |
| STK17A | serine/threonine kinase 17a | -0.0125306 |
| HLA-A | major histocompatibility complex, class I, A | -0.012475 |
| DIAPH1 | diaphanous-related formin 1 | -0.0123587 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0122908 |
| RPL9 | ribosomal protein L9 | -0.0120636 |
| NDRG1 | N-myc downstream regulated 1 | -0.0119602 |
| FMNL2 | formin-like 2 | -0.0119487 |
| CLIC4 | chloride intracellular channel 4 | -0.011946 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0119445 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0117762 |
| ATP10A | ATPase, class V, type 10A | -0.0117667 |
| RIGI | RNA sensor RIG-I | -0.0115542 |
| S100P | S100 calcium binding protein P | -0.0115331 |
| CD63 | CD63 molecule | -0.011371 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0113442 |
| ATF6 | activating transcription factor 6 | -0.0111124 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0111082 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0109836 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.01098 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0109661 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0108585 |
| HPCAL1 | hippocalcin-like 1 | -0.0108207 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0107805 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0106429 |
| MAP1B | microtubule-associated protein 1B | -0.0106199 |
| ITGA6 | integrin, alpha 6 | -0.0106149 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0105743 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0105281 |
| PGK1 | phosphoglycerate kinase 1 | -0.0104991 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0104059 |
| MYO1E | myosin IE | -0.0104011 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.010241 |
| MYO6 | myosin VI | -0.0100761 |
| RPS20 | ribosomal protein S20 | -0.0100646 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0100521 |
| KLF6 | Kruppel-like factor 6 | -0.00998257 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.00995475 |
| MT2A | metallothionein 2A | -0.00984864 |
