| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.165656 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0899511 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0807483 |
| FLNA | filamin A, alpha | 0.0685975 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0601737 |
| PLEC | plectin | 0.052628 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0520091 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0499238 |
| NRG1 | neuregulin 1 | 0.0482319 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0480708 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0417594 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417167 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0387436 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.038021 |
| SLTM | SAFB-like, transcription modulator | 0.0380112 |
| PLK2 | polo-like kinase 2 | 0.0367692 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0364743 |
| CALR | calreticulin | 0.0344884 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0335256 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0332578 |
| MKI67 | marker of proliferation Ki-67 | 0.0332355 |
| CAVIN1 | caveolae associated protein 1 | 0.0330467 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0327359 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0321588 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.030933 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0309029 |
| ITGA6 | integrin, alpha 6 | 0.0275125 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270831 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.027069 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0267888 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0250744 |
| AMOTL1 | angiomotin like 1 | 0.0250639 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0250218 |
| CENPF | centromere protein F, 350/400kDa | 0.0247816 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0238598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238047 |
| KRT6A | keratin 6A, type II | 0.0237514 |
| PLAT | plasminogen activator, tissue | 0.0227584 |
| RASA3 | RAS p21 protein activator 3 | 0.022637 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0224539 |
| PCDH1 | protocadherin 1 | 0.02242 |
| ANXA3 | annexin A3 | 0.0216137 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0202637 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0197939 |
| EPHA2 | EPH receptor A2 | 0.0195977 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0193888 |
| NMT2 | N-myristoyltransferase 2 | 0.0192125 |
| YOD1 | YOD1 deubiquitinase | 0.019177 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0191473 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0187781 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.018557 |
| GOLGA4 | golgin A4 | 0.0184819 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0183202 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.018156 |
| CNN3 | calponin 3, acidic | 0.0177047 |
| TNS3 | tensin 3 | 0.017402 |
| EHBP1 | EH domain binding protein 1 | 0.0173225 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0172398 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0170929 |
| RASAL2 | RAS protein activator like 2 | 0.0166777 |
| LAMC2 | laminin, gamma 2 | 0.0166484 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0164709 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0164291 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0162555 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0161683 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0161548 |
| RPL3 | ribosomal protein L3 | 0.0160909 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0159769 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0159473 |
| COG6 | component of oligomeric golgi complex 6 | 0.0159471 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0158181 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0158034 |
| USP47 | ubiquitin specific peptidase 47 | 0.015691 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0156126 |
| BDNF | brain-derived neurotrophic factor | 0.0155776 |
| THBS1 | thrombospondin 1 | 0.0153889 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.015282 |
| QKI | QKI, KH domain containing, RNA binding | 0.015187 |
| FOSL1 | FOS-like antigen 1 | 0.0148473 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0148053 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0147696 |
| AFAP1 | actin filament associated protein 1 | 0.0146856 |
| LAMB1 | laminin, beta 1 | 0.0146674 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0146414 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0145866 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.014469 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0144345 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0144318 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0143863 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0143776 |
| TGFB2 | transforming growth factor, beta 2 | 0.0142956 |
| SAV1 | salvador family WW domain containing protein 1 | 0.0142714 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0142619 |
| TXNRD1 | thioredoxin reductase 1 | 0.0142479 |
| MYO10 | myosin X | 0.0141777 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.014099 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0140553 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0139345 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0138844 |
| ARF4 | ADP-ribosylation factor 4 | 0.0137018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | -0.186109 |
| NDRG1 | N-myc downstream regulated 1 | -0.179711 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.118384 |
| MEF2A | myocyte enhancer factor 2A | -0.113896 |
| LDHA | lactate dehydrogenase A | -0.107563 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.106829 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0928983 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0889221 |
| CD44 | CD44 molecule (Indian blood group) | -0.0797952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0741115 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0720988 |
| B2M | beta-2-microglobulin | -0.0707588 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0697559 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0648956 |
| LMO7 | LIM domain 7 | -0.0639958 |
| RIGI | RNA sensor RIG-I | -0.0616043 |
| RPS21 | ribosomal protein S21 | -0.0591084 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0572807 |
| PGK1 | phosphoglycerate kinase 1 | -0.0565852 |
| FOXO1 | forkhead box O1 | -0.0521796 |
| TXNIP | thioredoxin interacting protein | -0.0507059 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0496806 |
| KIAA1217 | KIAA1217 | -0.0469317 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0464023 |
| FOXP1 | forkhead box P1 | -0.0463797 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0452116 |
| RAI14 | retinoic acid induced 14 | -0.0449095 |
| RPLP1 | ribosomal protein, large, P1 | -0.0448651 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0447888 |
| HLA-B | major histocompatibility complex, class I, B | -0.0444922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0440423 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0437837 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0436883 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0433171 |
| DOK5 | docking protein 5 | -0.0431116 |
| ASPH | aspartate beta-hydroxylase | -0.0424864 |
| LMNA | lamin A/C | -0.0420176 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0419932 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0417554 |
| MSN | moesin | -0.0417246 |
| IFI44 | interferon-induced protein 44 | -0.0408565 |
| SEPTIN9 | septin 9 | -0.0406385 |
| PLS3 | plastin 3 | -0.0405721 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0400392 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0398298 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0393884 |
| JMJD1C | jumonji domain containing 1C | -0.0393479 |
| STC1 | stanniocalcin 1 | -0.0390199 |
| PALLD | palladin, cytoskeletal associated protein | -0.0380083 |
| CLU | clusterin | -0.0379939 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0376709 |
| IFI44L | interferon-induced protein 44-like | -0.0375105 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0373498 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0371255 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0368075 |
| EMP1 | epithelial membrane protein 1 | -0.0365854 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0365826 |
| MT2A | metallothionein 2A | -0.0362392 |
| AOPEP | aminopeptidase O (putative) | -0.0360845 |
| RPS8 | ribosomal protein S8 | -0.0355822 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0354813 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0353856 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0346435 |
| RPS2 | ribosomal protein S2 | -0.0345541 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0344044 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0342504 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0342081 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0338941 |
| MYOF | myoferlin | -0.0338186 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0337567 |
| SULF2 | sulfatase 2 | -0.0336933 |
| YBX3 | Y box binding protein 3 | -0.0330497 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0330118 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0328758 |
| CD9 | CD9 molecule | -0.0328019 |
| RAB10 | RAB10, member RAS oncogene family | -0.0326663 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0322255 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0319181 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0314325 |
| RPS13 | ribosomal protein S13 | -0.0313893 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0312528 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0311959 |
| DIAPH1 | diaphanous-related formin 1 | -0.0299403 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0299363 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0298582 |
| RBM39 | RNA binding motif protein 39 | -0.0295869 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0294915 |
| PKM | pyruvate kinase, muscle | -0.0294777 |
| TGM2 | transglutaminase 2 | -0.0294327 |
| DSG2 | desmoglein 2 | -0.0293361 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0293089 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0292646 |
| MCL1 | myeloid cell leukemia 1 | -0.0291046 |
| ANXA1 | annexin A1 | -0.0289949 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0288409 |
| TAGLN2 | transgelin 2 | -0.0287059 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0285813 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0284164 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0280055 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0279221 |
