| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daptomycin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.203486 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.190638 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.149627 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.140067 |
| TXNRD1 | thioredoxin reductase 1 | 0.110164 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.110029 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.108193 |
| FLNB | filamin B, beta | 0.0939547 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0885486 |
| RAI1 | retinoic acid induced 1 | 0.0882076 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0822004 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0804588 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0801215 |
| FMNL2 | formin-like 2 | 0.0790439 |
| PLK2 | polo-like kinase 2 | 0.0763972 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0762235 |
| EZR | ezrin | 0.0716387 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0707079 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.069744 |
| EREG | epiregulin | 0.0689384 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0688786 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0681334 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0674618 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0661122 |
| MKI67 | marker of proliferation Ki-67 | 0.0655661 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0649365 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0636714 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0617187 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0598816 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0596002 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0591507 |
| ENO1 | enolase 1, (alpha) | 0.0583569 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0560036 |
| CENPF | centromere protein F, 350/400kDa | 0.0559764 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0553181 |
| DST | dystonin | 0.0551161 |
| CD44 | CD44 molecule (Indian blood group) | 0.054828 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0547569 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0544219 |
| CMIP | c-Maf inducing protein | 0.0540882 |
| DIAPH3 | diaphanous-related formin 3 | 0.05373 |
| FERMT1 | fermitin family member 1 | 0.0536197 |
| RTN4 | reticulon 4 | 0.0533056 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0500876 |
| KRT18 | keratin 18, type I | 0.0499083 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0488292 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0476777 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0475764 |
| SET | SET nuclear proto-oncogene | 0.0469216 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0467277 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0458918 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0458715 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0458008 |
| TPM3 | tropomyosin 3 | 0.0449499 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0440712 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.042847 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0421078 |
| RASA2 | RAS p21 protein activator 2 | 0.0420776 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0419804 |
| FUS | FUS RNA binding protein | 0.041675 |
| TPM4 | tropomyosin 4 | 0.0393175 |
| WDR43 | WD repeat domain 43 | 0.0390343 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0387175 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.03861 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0380756 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0380182 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0375112 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0373264 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0372399 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0370656 |
| AREG | amphiregulin | 0.0367939 |
| PODXL | podocalyxin-like | 0.0362869 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0360736 |
| SRPK1 | SRSF protein kinase 1 | 0.0358232 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0357566 |
| RASAL2 | RAS protein activator like 2 | 0.035385 |
| TFRC | transferrin receptor | 0.0341822 |
| RPS12 | ribosomal protein S12 | 0.0340248 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0339026 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0338125 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0336294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0335664 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0334598 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333027 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0329822 |
| RPLP2 | ribosomal protein, large, P2 | 0.0329109 |
| RBM25 | RNA binding motif protein 25 | 0.0329004 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0326526 |
| CAPRIN2 | caprin family member 2 | 0.0325159 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0321362 |
| CEP170 | centrosomal protein 170kDa | 0.0320922 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0315669 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0314665 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0313428 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0310882 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0310872 |
| RPS6 | ribosomal protein S6 | 0.0303071 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0298292 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0296266 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0292674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22279 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.108636 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.100295 |
| VIM | vimentin | -0.0993035 |
| LDHA | lactate dehydrogenase A | -0.0827466 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0785069 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0779525 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0726024 |
| TMSB10 | thymosin beta 10 | -0.0665138 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0636224 |
| PGK1 | phosphoglycerate kinase 1 | -0.0574139 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0524673 |
| TP63 | tumor protein p63 | -0.0514905 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476193 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0466748 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0456675 |
| EGR1 | early growth response 1 | -0.0422014 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0414643 |
| RPL35A | ribosomal protein L35a | -0.0390144 |
| RIGI | RNA sensor RIG-I | -0.0376854 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0360579 |
| HDAC9 | histone deacetylase 9 | -0.035789 |
| SQSTM1 | sequestosome 1 | -0.0351659 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0329935 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0326111 |
| TUBB | tubulin, beta class I | -0.032012 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0310327 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0299736 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0298271 |
| PHF21A | PHD finger protein 21A | -0.0295731 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0289784 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0287868 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0283585 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0281581 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0277754 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0277703 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0276907 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0275059 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0270664 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0264766 |
| TAPBP | TAP binding protein (tapasin) | -0.0262816 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0262083 |
| RPLP1 | ribosomal protein, large, P1 | -0.02538 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.025214 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.024808 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0247241 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0246998 |
| FTL | ferritin, light polypeptide | -0.0243059 |
| PTMA | prothymosin, alpha | -0.0240075 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.023466 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0233171 |
| AHNAK | AHNAK nucleoprotein | -0.0232011 |
| TUT4 | terminal uridylyl transferase 4 | -0.0231002 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0230243 |
| PHF3 | PHD finger protein 3 | -0.0224832 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0224027 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0220447 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0219288 |
| SMYD3 | SET and MYND domain containing 3 | -0.0216511 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0215009 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0214457 |
| ANGPTL4 | angiopoietin-like 4 | -0.0212942 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0212745 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0208386 |
| MT1X | metallothionein 1X | -0.0207104 |
| KLHL24 | kelch-like family member 24 | -0.0205801 |
| NBEAL1 | neurobeachin-like 1 | -0.02051 |
| STAG2 | stromal antigen 2 | -0.0201822 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0199809 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0199299 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0198347 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0195241 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0195105 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0194745 |
| ARRDC3 | arrestin domain containing 3 | -0.0194368 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0194169 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0191316 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0189967 |
| TMEM123 | transmembrane protein 123 | -0.0189178 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.018823 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0188149 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.018704 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186502 |
| ZNF292 | zinc finger protein 292 | -0.0183732 |
| LASP1 | LIM and SH3 protein 1 | -0.0183601 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0183366 |
| ERBIN | erbb2 interacting protein | -0.0183338 |
| ITGB4 | integrin, beta 4 | -0.0183191 |
| RTN3 | reticulon 3 | -0.0183002 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0182774 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0182682 |
| LRRC49 | leucine rich repeat containing 49 | -0.0182645 |
| TRERF1 | transcriptional regulating factor 1 | -0.0182076 |
| DENND5B | DENN/MADD domain containing 5B | -0.0181559 |
| SNX14 | sorting nexin 14 | -0.018066 |
| CD109 | CD109 molecule | -0.017984 |
| MED13 | mediator complex subunit 13 | -0.0178153 |
| UBE4B | ubiquitination factor E4B | -0.0175812 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0175629 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0174588 |
