| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daptomycin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | 0.131794 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.120134 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.117659 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0900971 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0846252 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.077317 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0676677 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0636005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0588704 |
| THBS1 | thrombospondin 1 | 0.0558883 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0538481 |
| FMNL2 | formin-like 2 | 0.0517165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0510074 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0456435 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0453355 |
| TPM3 | tropomyosin 3 | 0.0444429 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.04404 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0437196 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0433579 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0432359 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0426769 |
| CAVIN1 | caveolae associated protein 1 | 0.042016 |
| CALR | calreticulin | 0.0413775 |
| QKI | QKI, KH domain containing, RNA binding | 0.0394894 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0394712 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0394497 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.039078 |
| GOLGA4 | golgin A4 | 0.0390406 |
| FLNA | filamin A, alpha | 0.0388349 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0387283 |
| DST | dystonin | 0.0355038 |
| STC1 | stanniocalcin 1 | 0.0345437 |
| RPS2 | ribosomal protein S2 | 0.0341714 |
| NRG1 | neuregulin 1 | 0.0326942 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0324914 |
| PTMA | prothymosin, alpha | 0.0323842 |
| APP | amyloid beta (A4) precursor protein | 0.0323574 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0320914 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0320863 |
| UBC | ubiquitin C | 0.0315904 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.030535 |
| EGFR | epidermal growth factor receptor | 0.0302998 |
| ACTG1 | actin gamma 1 | 0.0301151 |
| CANX | calnexin | 0.029559 |
| KIF5B | kinesin family member 5B | 0.0293932 |
| MYOF | myoferlin | 0.029051 |
| AHR | aryl hydrocarbon receptor | 0.0285669 |
| ANXA1 | annexin A1 | 0.0285164 |
| COG5 | component of oligomeric golgi complex 5 | 0.0283117 |
| RPS6 | ribosomal protein S6 | 0.0282485 |
| CCNL1 | cyclin L1 | 0.0281822 |
| FGB | fibrinogen beta chain | 0.0281461 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0277594 |
| RPL19 | ribosomal protein L19 | 0.0276003 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0272685 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.027143 |
| RPL4 | ribosomal protein L4 | 0.0270835 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0270324 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0268273 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0265933 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0263802 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0260467 |
| ADM | adrenomedullin | 0.0259826 |
| KLC1 | kinesin light chain 1 | 0.0256773 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0255186 |
| PAPOLA | poly(A) polymerase alpha | 0.0253631 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0253042 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0253037 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0250665 |
| RASAL2 | RAS protein activator like 2 | 0.0248025 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0246997 |
| RPS27A | ribosomal protein S27a | 0.0245775 |
| AHNAK | AHNAK nucleoprotein | 0.0244043 |
| NCKAP1 | NCK-associated protein 1 | 0.0242203 |
| FLNB | filamin B, beta | 0.0237992 |
| SPAG9 | sperm associated antigen 9 | 0.0235974 |
| RPL38 | ribosomal protein L38 | 0.0235024 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0230549 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0228636 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0228174 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0226154 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0226107 |
| JAK1 | Janus kinase 1 | 0.0224656 |
| S100A10 | S100 calcium binding protein A10 | 0.0220144 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0220107 |
| NUP153 | nucleoporin 153kDa | 0.0220034 |
| CALU | calumenin | 0.0219584 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0218666 |
| TGFB2 | transforming growth factor, beta 2 | 0.0216375 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0214178 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0214064 |
| FNBP1L | formin binding protein 1-like | 0.0213718 |
| BRD2 | bromodomain containing 2 | 0.0213608 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0213422 |
| NOB1 | NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) | 0.021229 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0212057 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.021167 |
| SLC38A2 | solute carrier family 38, member 2 | 0.020792 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0207832 |
| CLU | clusterin | 0.0207679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.279317 |
| PM20D1 | peptidase M20 domain containing 1 | -0.167873 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.140031 |
| GRAMD1B | GRAM domain containing 1B | -0.109138 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.077086 |
| EGR1 | early growth response 1 | -0.0754514 |
| TMSB10 | thymosin beta 10 | -0.0741275 |
| POTEF | POTE ankyrin domain family, member F | -0.0709381 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0595253 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0576771 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0546476 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0545987 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0485376 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476596 |
| RPL35A | ribosomal protein L35a | -0.047434 |
| RPLP1 | ribosomal protein, large, P1 | -0.0398887 |
| LDHA | lactate dehydrogenase A | -0.0380129 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0362341 |
| RPL7 | ribosomal protein L7 | -0.03609 |
| FAM107B | family with sequence similarity 107, member B | -0.0351433 |
| KYNU | kynureninase | -0.0345396 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.034109 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0338784 |
| PKM | pyruvate kinase, muscle | -0.0319918 |
| TUBB | tubulin, beta class I | -0.0309129 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0296439 |
| FTL | ferritin, light polypeptide | -0.0284296 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282131 |
| YBX1 | Y box binding protein 1 | -0.0279736 |
| TAGLN2 | transgelin 2 | -0.0276091 |
| RPS21 | ribosomal protein S21 | -0.027417 |
| RHOA | ras homolog family member A | -0.0269298 |
| RAD51B | RAD51 paralog B | -0.0267501 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0267265 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0263817 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0263776 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0254804 |
| HDAC9 | histone deacetylase 9 | -0.0254365 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0253651 |
| ECT2 | epithelial cell transforming 2 | -0.0247938 |
| CMIP | c-Maf inducing protein | -0.0246778 |
| SVIL | supervillin | -0.0243152 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0238023 |
| NHSL1 | NHS-like 1 | -0.0236334 |
| TUBA1B | tubulin, alpha 1b | -0.0235031 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0228062 |
| ATP5F1A | ATP synthase F1 subunit alpha | -0.0225401 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.022339 |
| RPL23 | ribosomal protein L23 | -0.0223313 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0219569 |
| RPS20 | ribosomal protein S20 | -0.0216691 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0214392 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0209586 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0208476 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.020638 |
| RPS23 | ribosomal protein S23 | -0.0203735 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0196498 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0195467 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0193211 |
| PFN1 | profilin 1 | -0.0192976 |
| DEK | DEK proto-oncogene | -0.0192433 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0187923 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0183936 |
| HMGB1 | high mobility group box 1 | -0.0179596 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0178693 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.01773 |
| CENPE | centromere protein E, 312kDa | -0.0174361 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.017237 |
| PLS3 | plastin 3 | -0.016847 |
| OSMR | oncostatin M receptor | -0.0167206 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0166178 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0166159 |
| MORF4L2 | mortality factor 4 like 2 | -0.0166045 |
| NUP98 | nucleoporin 98kDa | -0.0165321 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0164714 |
| GPATCH2L | G patch domain containing 2-like | -0.0163384 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0161968 |
| NUP58 | nucleoporin 58 | -0.0160019 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0157714 |
| EFNA5 | ephrin-A5 | -0.015698 |
| NTN4 | netrin 4 | -0.0156326 |
| MCL1 | myeloid cell leukemia 1 | -0.0154855 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0154447 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0153579 |
| RPL27 | ribosomal protein L27 | -0.0151963 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.015166 |
| PRDX1 | peroxiredoxin 1 | -0.0150194 |
| S100A11 | S100 calcium binding protein A11 | -0.0148189 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0147833 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0147802 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0145829 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0145576 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0145007 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0144229 |
| RPS29 | ribosomal protein S29 | -0.0143992 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0143949 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | -0.0142895 |
| RRM2 | ribonucleotide reductase M2 | -0.0142513 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.014049 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0140114 |
