| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.100506 |
| DST | dystonin | 0.0957572 |
| PTK2 | protein tyrosine kinase 2 | 0.0678745 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0648486 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0638153 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0621423 |
| PRELID2 | PRELI domain containing 2 | 0.0568673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0560774 |
| BBX | bobby sox homolog (Drosophila) | 0.0533414 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0527662 |
| AREG | amphiregulin | 0.0503793 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0499154 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0493653 |
| GPC6 | glypican 6 | 0.0482174 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0471308 |
| TPR | translocated promoter region, nuclear basket protein | 0.0468069 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0466932 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0465618 |
| NCKAP1 | NCK-associated protein 1 | 0.0462579 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0457802 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0417403 |
| RTN4 | reticulon 4 | 0.0413897 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0411722 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0410517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.040232 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0401798 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0394302 |
| SERINC5 | serine incorporator 5 | 0.0391028 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0374706 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0374483 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0370346 |
| MKI67 | marker of proliferation Ki-67 | 0.0368265 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0365346 |
| OXR1 | oxidation resistance 1 | 0.0363276 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0361728 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0360766 |
| CENPF | centromere protein F, 350/400kDa | 0.0360175 |
| SCEL | sciellin | 0.0358047 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0354086 |
| DENND4C | DENN/MADD domain containing 4C | 0.0352987 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.034817 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0346798 |
| TPD52 | tumor protein D52 | 0.0346153 |
| ENO1 | enolase 1, (alpha) | 0.0343591 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0342997 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0339393 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0338226 |
| NEK7 | NIMA-related kinase 7 | 0.0336311 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0334339 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0334268 |
| EXOC4 | exocyst complex component 4 | 0.0333084 |
| COPA | coatomer protein complex, subunit alpha | 0.0331552 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0329792 |
| COL5A2 | collagen, type V, alpha 2 | 0.0327636 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0324449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0323326 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.032324 |
| VMP1 | vacuole membrane protein 1 | 0.0322023 |
| SETD5 | SET domain containing 5 | 0.0317807 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315946 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0315601 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0315515 |
| PYGL | phosphorylase, glycogen, liver | 0.0312477 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0309303 |
| TFG | TRK-fused gene | 0.0305321 |
| TPM3 | tropomyosin 3 | 0.0303607 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0303531 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0299863 |
| CA12 | carbonic anhydrase XII | 0.029873 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0298585 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0295333 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0295217 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0287559 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0285929 |
| SRPK2 | SRSF protein kinase 2 | 0.0284608 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0284005 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0282334 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0281779 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0281729 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0280759 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.027873 |
| PHF21A | PHD finger protein 21A | 0.0277728 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0277198 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0276269 |
| UBE3C | ubiquitin protein ligase E3C | 0.0273503 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0272803 |
| PDE10A | phosphodiesterase 10A | 0.0271098 |
| FAM168A | family with sequence similarity 168, member A | 0.0269883 |
| NKTR | natural killer cell triggering receptor | 0.0268568 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0267553 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0265576 |
| LAMA4 | laminin, alpha 4 | 0.0264417 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0264392 |
| OXSR1 | oxidative stress responsive 1 | 0.026303 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0262677 |
| ZNF654 | zinc finger protein 654 | 0.0262202 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0260138 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258641 |
| SMYD3 | SET and MYND domain containing 3 | 0.0258526 |
| CD44 | CD44 molecule (Indian blood group) | 0.025826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.180909 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.137737 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.125521 |
| IGF2 | insulin-like growth factor 2 | -0.108872 |
| ATOSA | atos homolog A | -0.10231 |
| LAMB3 | laminin, beta 3 | -0.0983986 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.090018 |
| MT2A | metallothionein 2A | -0.0882751 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0842082 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0820085 |
| TMSB10 | thymosin beta 10 | -0.0729805 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0717585 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0690243 |
| MUC16 | mucin 16, cell surface associated | -0.0682953 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0664244 |
| SVIL | supervillin | -0.0629319 |
| ABHD17C | abhydrolase domain containing 17C | -0.0590266 |
| RBM47 | RNA binding motif protein 47 | -0.0583887 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0569241 |
| FTL | ferritin, light polypeptide | -0.056824 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0547328 |
| KYNU | kynureninase | -0.0537048 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0527215 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0522398 |
| MYO1E | myosin IE | -0.0521181 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0500852 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0497781 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0495636 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0492608 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0477836 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0472214 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0471773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0468021 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0457882 |
| EGFR | epidermal growth factor receptor | -0.0455481 |
| SQSTM1 | sequestosome 1 | -0.0448183 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0430218 |
| RPS16 | ribosomal protein S16 | -0.0430012 |
| ERBIN | erbb2 interacting protein | -0.0414832 |
| USP34 | ubiquitin specific peptidase 34 | -0.0413323 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0408317 |
| EFNA5 | ephrin-A5 | -0.0407801 |
| CD2AP | CD2-associated protein | -0.0397278 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0396374 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0388386 |
| RAB10 | RAB10, member RAS oncogene family | -0.0387318 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0381029 |
| MEF2A | myocyte enhancer factor 2A | -0.0379397 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0378804 |
| ZNF638 | zinc finger protein 638 | -0.0377026 |
| TXNRD1 | thioredoxin reductase 1 | -0.0374727 |
| VIM | vimentin | -0.0373616 |
| EZR | ezrin | -0.0359767 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0357343 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0352853 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0351526 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0351007 |
| LOXL2 | lysyl oxidase-like 2 | -0.0346949 |
| OSMR | oncostatin M receptor | -0.0344977 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034325 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0340167 |
| C3 | complement component 3 | -0.0338714 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.033737 |
| CDK13 | cyclin-dependent kinase 13 | -0.0333355 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0332395 |
| AHNAK | AHNAK nucleoprotein | -0.0331457 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0329006 |
| NPTN | neuroplastin | -0.0322564 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0320515 |
| DUSP16 | dual specificity phosphatase 16 | -0.0318445 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0317113 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0315893 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0315006 |
| STC1 | stanniocalcin 1 | -0.0310888 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0310281 |
| BPTF | bromodomain PHD finger transcription factor | -0.0310132 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0309996 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0300562 |
| KLF6 | Kruppel-like factor 6 | -0.0300166 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0299755 |
| RPL11 | ribosomal protein L11 | -0.0295752 |
| FOXO1 | forkhead box O1 | -0.0294725 |
| KIAA1217 | KIAA1217 | -0.0291341 |
| TJP1 | tight junction protein 1 | -0.0291022 |
| SNX6 | sorting nexin 6 | -0.0290953 |
| ZNF207 | zinc finger protein 207 | -0.0290168 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0289974 |
| FAM13A | family with sequence similarity 13, member A | -0.0288502 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0287551 |
| RPS14 | ribosomal protein S14 | -0.0281849 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0281481 |
| TUSC3 | tumor suppressor candidate 3 | -0.0280795 |
| ITGB4 | integrin, beta 4 | -0.0276295 |
| MYO5C | myosin VC | -0.0271237 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0270321 |
| USP6NL | USP6 N-terminal like | -0.0268888 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0267707 |
| RPL37A | ribosomal protein L37a | -0.0266498 |
| RPL31 | ribosomal protein L31 | -0.0265776 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0264643 |
