| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daptomycin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.259527 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.110641 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108274 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.106827 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0877143 |
| LAMC2 | laminin, gamma 2 | 0.0833686 |
| UBC | ubiquitin C | 0.0712256 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0710019 |
| NAV2 | neuron navigator 2 | 0.0701272 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.066229 |
| DTNA | dystrobrevin, alpha | 0.0536567 |
| DSPP | dentin sialophosphoprotein | 0.0526205 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0517232 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0500741 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0469784 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0438205 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0429586 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0428334 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0428194 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0425098 |
| TPM3 | tropomyosin 3 | 0.0424746 |
| CALR | calreticulin | 0.042164 |
| MAP1B | microtubule-associated protein 1B | 0.0419128 |
| MX1 | MX dynamin-like GTPase 1 | 0.0410598 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0390788 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.038965 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0382982 |
| MSN | moesin | 0.0375293 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0336546 |
| ENO1 | enolase 1, (alpha) | 0.0330138 |
| SLTM | SAFB-like, transcription modulator | 0.0326541 |
| TXNRD1 | thioredoxin reductase 1 | 0.0324917 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0324532 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0321873 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0320132 |
| CENPF | centromere protein F, 350/400kDa | 0.0312155 |
| FLNA | filamin A, alpha | 0.0306146 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303634 |
| RPL3 | ribosomal protein L3 | 0.0301502 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0292786 |
| PLEC | plectin | 0.029164 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.028442 |
| MKI67 | marker of proliferation Ki-67 | 0.0278747 |
| TMSB4X | thymosin beta 4, X-linked | 0.0278188 |
| CCNL1 | cyclin L1 | 0.0266057 |
| EFNA5 | ephrin-A5 | 0.0265075 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0265075 |
| TMF1 | TATA element modulatory factor 1 | 0.0264709 |
| HDGF | hepatoma-derived growth factor | 0.0264432 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0259837 |
| CDCP1 | CUB domain containing protein 1 | 0.0248821 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0248732 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0246523 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0245331 |
| MYO5B | myosin VB | 0.0243568 |
| RAD51B | RAD51 paralog B | 0.0241697 |
| SP100 | SP100 nuclear antigen | 0.0240139 |
| VEGFA | vascular endothelial growth factor A | 0.0238708 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0236998 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0234061 |
| ASPH | aspartate beta-hydroxylase | 0.0232804 |
| FHIT | fragile histidine triad | 0.0228436 |
| FLNB | filamin B, beta | 0.0227312 |
| RNF213 | ring finger protein 213 | 0.0224116 |
| DST | dystonin | 0.0221602 |
| FBXO32 | F-box protein 32 | 0.0219497 |
| CTSB | cathepsin B | 0.0216403 |
| RPS3A | ribosomal protein S3A | 0.0214359 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0213168 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.021208 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0208353 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0207879 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0206946 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203665 |
| ADM | adrenomedullin | 0.0201834 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0196913 |
| FMNL2 | formin-like 2 | 0.0196083 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.019495 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0190728 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0190459 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0188221 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0184598 |
| MYO6 | myosin VI | 0.0183801 |
| CTSS | cathepsin S | 0.0182337 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.018219 |
| TPM4 | tropomyosin 4 | 0.0180915 |
| GOLGB1 | golgin B1 | 0.0180317 |
| SET | SET nuclear proto-oncogene | 0.0179466 |
| ADAR | adenosine deaminase, RNA-specific | 0.0177208 |
| RPS6 | ribosomal protein S6 | 0.0176482 |
| CTTN | cortactin | 0.0176067 |
| IFI44L | interferon-induced protein 44-like | 0.0170788 |
| CNN3 | calponin 3, acidic | 0.0167208 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0167016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0166173 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0164823 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.016325 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.016085 |
| CKAP5 | cytoskeleton associated protein 5 | 0.015995 |
| CD151 | CD151 molecule (Raph blood group) | 0.0159735 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.207955 |
| RPL35A | ribosomal protein L35a | -0.121087 |
| FN1 | fibronectin 1 | -0.11181 |
| TMSB10 | thymosin beta 10 | -0.10761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0964533 |
| HMGA1 | high mobility group AT-hook 1 | -0.0961818 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0855119 |
| RPLP1 | ribosomal protein, large, P1 | -0.0805691 |
| PTMA | prothymosin, alpha | -0.078874 |
| LDHA | lactate dehydrogenase A | -0.0779161 |
| NDRG1 | N-myc downstream regulated 1 | -0.0701002 |
| ACTG1 | actin gamma 1 | -0.0680734 |
| POTEF | POTE ankyrin domain family, member F | -0.065394 |
| ANXA2 | annexin A2 | -0.0649303 |
| FTL | ferritin, light polypeptide | -0.0628883 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0610955 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0597755 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0591508 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0588033 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0580141 |
| HMGB2 | high mobility group box 2 | -0.0566873 |
| RPL34 | ribosomal protein L34 | -0.0526673 |
| PGK1 | phosphoglycerate kinase 1 | -0.0523052 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0516419 |
| S100A6 | S100 calcium binding protein A6 | -0.0507633 |
| RHOA | ras homolog family member A | -0.0504835 |
| SDC4 | syndecan 4 | -0.0504593 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0488554 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0460645 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0458916 |
| LAMB3 | laminin, beta 3 | -0.0451987 |
| MT2A | metallothionein 2A | -0.0442643 |
| NEK7 | NIMA-related kinase 7 | -0.0435349 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0427425 |
| RPL23 | ribosomal protein L23 | -0.0418458 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0413901 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0411083 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.040519 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0404743 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.040019 |
| TUBA1B | tubulin, alpha 1b | -0.0398475 |
| RPL30 | ribosomal protein L30 | -0.0396061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395636 |
| RHEB | Ras homolog enriched in brain | -0.0390753 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0389026 |
| RBM39 | RNA binding motif protein 39 | -0.0387168 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0385616 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0385592 |
| RPS23 | ribosomal protein S23 | -0.0379467 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0377453 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0375365 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0372904 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0363371 |
| USP3 | ubiquitin specific peptidase 3 | -0.0358839 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0358726 |
| RPL7 | ribosomal protein L7 | -0.0355445 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0353385 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0346062 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0344488 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0342084 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0337311 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.032856 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0324522 |
| TFG | TRK-fused gene | -0.0324037 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0320098 |
| PKM | pyruvate kinase, muscle | -0.0317132 |
| MEF2A | myocyte enhancer factor 2A | -0.0316907 |
| USP15 | ubiquitin specific peptidase 15 | -0.0316215 |
| RPS19 | ribosomal protein S19 | -0.0315608 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0312016 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0310559 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0309931 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0309076 |
| TUBB | tubulin, beta class I | -0.0308863 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.030852 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0306319 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0305774 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0303826 |
| TJP1 | tight junction protein 1 | -0.0303423 |
| TKT | transketolase | -0.0301669 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300065 |
| RPS24 | ribosomal protein S24 | -0.0300047 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0296782 |
| CERT1 | ceramide transporter 1 | -0.0292881 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0291693 |
| GNAS | GNAS complex locus | -0.0291046 |
| H3-3B | H3.3 histone B | -0.0284798 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.028468 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0283792 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0276623 |
| DEK | DEK proto-oncogene | -0.0275665 |
| RPS13 | ribosomal protein S13 | -0.0275158 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0274559 |
| RPL8 | ribosomal protein L8 | -0.0273483 |
| RPL27A | ribosomal protein L27a | -0.0273237 |
| ARF1 | ADP-ribosylation factor 1 | -0.0273004 |
| EGR1 | early growth response 1 | -0.0271337 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0270146 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0267622 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0261836 |
