| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.143676 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.102489 |
| TXNRD1 | thioredoxin reductase 1 | 0.0917508 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0901683 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0755952 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0736413 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0659418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0650335 |
| MKI67 | marker of proliferation Ki-67 | 0.0640138 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0633368 |
| GRAMD1B | GRAM domain containing 1B | 0.0618105 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0598997 |
| FN1 | fibronectin 1 | 0.0571608 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0514985 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0510131 |
| CANX | calnexin | 0.0491408 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0472554 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0468107 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0458859 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0450123 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0442172 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0427517 |
| CENPF | centromere protein F, 350/400kDa | 0.0406698 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0388086 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0376247 |
| NEK7 | NIMA-related kinase 7 | 0.035429 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0354129 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0347632 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0341007 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0335939 |
| FLNA | filamin A, alpha | 0.0335694 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0335471 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.033467 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0333094 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0330685 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0329321 |
| FUS | FUS RNA binding protein | 0.0324661 |
| GDA | guanine deaminase | 0.0313722 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0309858 |
| ASPH | aspartate beta-hydroxylase | 0.0306096 |
| SET | SET nuclear proto-oncogene | 0.0305953 |
| PRKD3 | protein kinase D3 | 0.0304979 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0299825 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0290544 |
| RPL4 | ribosomal protein L4 | 0.028946 |
| RPL38 | ribosomal protein L38 | 0.0288517 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283156 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0281345 |
| ZNF804A | zinc finger protein 804A | 0.0281116 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.027979 |
| TPM3 | tropomyosin 3 | 0.0274737 |
| LAMB1 | laminin, beta 1 | 0.0270177 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0269609 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0267534 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.0265693 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0264604 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0263793 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0254982 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.025475 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0254109 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0253211 |
| ENAH | enabled homolog (Drosophila) | 0.0251469 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0250438 |
| LAMA1 | laminin, alpha 1 | 0.0249747 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0244019 |
| CDK6 | cyclin-dependent kinase 6 | 0.0238619 |
| TMSB4X | thymosin beta 4, X-linked | 0.0238137 |
| PTGR1 | prostaglandin reductase 1 | 0.023701 |
| GOLGA4 | golgin A4 | 0.0235312 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0233502 |
| CHML | choroideremia-like (Rab escort protein 2) | 0.0231989 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0230471 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0230039 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0228662 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0228626 |
| RPS3A | ribosomal protein S3A | 0.0226826 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0226496 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0225517 |
| NCKAP1 | NCK-associated protein 1 | 0.0222877 |
| MTAP | methylthioadenosine phosphorylase | 0.0220007 |
| PAPOLA | poly(A) polymerase alpha | 0.0217326 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0217022 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0215963 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0214356 |
| RPS2 | ribosomal protein S2 | 0.0213829 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0212566 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0212435 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0208747 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0207813 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0207037 |
| CBFB | core-binding factor, beta subunit | 0.0205795 |
| AHR | aryl hydrocarbon receptor | 0.0204496 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0204174 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0203884 |
| MYOF | myoferlin | 0.020326 |
| PDE10A | phosphodiesterase 10A | 0.0202846 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0201731 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0201445 |
| USP15 | ubiquitin specific peptidase 15 | 0.0201116 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0200422 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.165597 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.10629 |
| RPLP1 | ribosomal protein, large, P1 | -0.0988328 |
| TMSB10 | thymosin beta 10 | -0.0827192 |
| RPL35A | ribosomal protein L35a | -0.0774274 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0770798 |
| LDHA | lactate dehydrogenase A | -0.0673197 |
| VIM | vimentin | -0.0587971 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.05786 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0575846 |
| MT2A | metallothionein 2A | -0.0562642 |
| FTL | ferritin, light polypeptide | -0.0559063 |
| RPS23 | ribosomal protein S23 | -0.0558803 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0543997 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0525349 |
| STC1 | stanniocalcin 1 | -0.0508944 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0508686 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0472084 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0466439 |
| MCL1 | myeloid cell leukemia 1 | -0.0463954 |
| AUTS2 | autism susceptibility candidate 2 | -0.0463793 |
| NDRG1 | N-myc downstream regulated 1 | -0.0451941 |
| RPL7 | ribosomal protein L7 | -0.0450834 |
| RACK1 | receptor for activated C kinase 1 | -0.0432168 |
| B2M | beta-2-microglobulin | -0.0429509 |
| RPL31 | ribosomal protein L31 | -0.0426601 |
| RPL23 | ribosomal protein L23 | -0.0421239 |
| S100A6 | S100 calcium binding protein A6 | -0.0405153 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0403868 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0401183 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0393272 |
| HLA-A | major histocompatibility complex, class I, A | -0.0391576 |
| RPS8 | ribosomal protein S8 | -0.037873 |
| RPS19 | ribosomal protein S19 | -0.0378236 |
| KRT19 | keratin 19, type I | -0.0374852 |
| COL5A2 | collagen, type V, alpha 2 | -0.0361829 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0360007 |
| PYGL | phosphorylase, glycogen, liver | -0.0348864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0347481 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0343492 |
| RPLP0 | ribosomal protein, large, P0 | -0.0337509 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0336225 |
| RPL26 | ribosomal protein L26 | -0.0331361 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331052 |
| EGR1 | early growth response 1 | -0.0319727 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0318249 |
| RPL9 | ribosomal protein L9 | -0.0317478 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0314054 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0308542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.030528 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0304787 |
| TUBA1B | tubulin, alpha 1b | -0.0303874 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295695 |
| RHOA | ras homolog family member A | -0.0293722 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291842 |
| DTNA | dystrobrevin, alpha | -0.0291524 |
| RPS27 | ribosomal protein S27 | -0.0291193 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0290414 |
| RPS21 | ribosomal protein S21 | -0.0283765 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0282952 |
| RPS29 | ribosomal protein S29 | -0.0279228 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0278616 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0278056 |
| RPL36 | ribosomal protein L36 | -0.0275847 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274057 |
| LSAMP | limbic system-associated membrane protein | -0.0272482 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0269217 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0266689 |
| RPS13 | ribosomal protein S13 | -0.026609 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0264091 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0259712 |
| MAP7 | microtubule-associated protein 7 | -0.0258505 |
| RPS14 | ribosomal protein S14 | -0.0257544 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0256873 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0254499 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0253941 |
| RPS20 | ribosomal protein S20 | -0.0251755 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0250293 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0248868 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0248165 |
| YBX1 | Y box binding protein 1 | -0.0242804 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0241211 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0240137 |
| PCBP2 | poly(rC) binding protein 2 | -0.0239646 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0238777 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0237288 |
| LAMA5 | laminin, alpha 5 | -0.0234157 |
| RPS24 | ribosomal protein S24 | -0.0234048 |
| RPS4X | ribosomal protein S4, X-linked | -0.0230549 |
| ANXA2 | annexin A2 | -0.0229632 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.022741 |
| SMYD3 | SET and MYND domain containing 3 | -0.0223041 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0222218 |
| RPL37A | ribosomal protein L37a | -0.0220543 |
| RPL37 | ribosomal protein L37 | -0.0219976 |
| TUBB | tubulin, beta class I | -0.021787 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.021418 |
| RPL12 | ribosomal protein L12 | -0.0213572 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0212774 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.021142 |
