| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101804 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.100565 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0861238 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0813195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0765045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.076273 |
| DST | dystonin | 0.073638 |
| MKI67 | marker of proliferation Ki-67 | 0.0693871 |
| THBS1 | thrombospondin 1 | 0.066773 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0579807 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0533913 |
| ANXA1 | annexin A1 | 0.0531895 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0531417 |
| CFL2 | cofilin 2 (muscle) | 0.0464642 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0461371 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0459834 |
| TPM3 | tropomyosin 3 | 0.0438402 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0417085 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0394259 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0393428 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0377422 |
| H1-4 | H1.4 linker histone, cluster member | 0.0372877 |
| CCNL1 | cyclin L1 | 0.0369044 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0363635 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0359527 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0355634 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0354709 |
| PDGFC | platelet derived growth factor C | 0.0348692 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0348264 |
| SET | SET nuclear proto-oncogene | 0.0348216 |
| WDR43 | WD repeat domain 43 | 0.0347996 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0342349 |
| PCBP2 | poly(rC) binding protein 2 | 0.0339633 |
| COL5A2 | collagen, type V, alpha 2 | 0.0333072 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.032934 |
| RBM25 | RNA binding motif protein 25 | 0.0328585 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0326396 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0324523 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0322094 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0319799 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0319704 |
| TMSB4X | thymosin beta 4, X-linked | 0.0317911 |
| CENPF | centromere protein F, 350/400kDa | 0.0314927 |
| SRP54 | signal recognition particle 54kDa | 0.0314064 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0311076 |
| POTEF | POTE ankyrin domain family, member F | 0.0308137 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0307942 |
| CKAP2 | cytoskeleton associated protein 2 | 0.030678 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0303416 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0300705 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0300522 |
| CRY1 | cryptochrome circadian clock 1 | 0.0295256 |
| TFG | TRK-fused gene | 0.0294481 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0293308 |
| HMGA2 | high mobility group AT-hook 2 | 0.02915 |
| USP3 | ubiquitin specific peptidase 3 | 0.0291163 |
| SPAG9 | sperm associated antigen 9 | 0.0290481 |
| ANLN | anillin, actin binding protein | 0.0289948 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0285176 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0283153 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0280053 |
| MATR3 | matrin 3 | 0.0279201 |
| IL6ST | interleukin 6 signal transducer | 0.0279125 |
| CANX | calnexin | 0.0276914 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0276694 |
| MB21D2 | Mab-21 domain containing 2 | 0.0275585 |
| FLNA | filamin A, alpha | 0.0272431 |
| KIF5B | kinesin family member 5B | 0.0271095 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0270971 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0268489 |
| ENAH | enabled homolog (Drosophila) | 0.0268403 |
| RPL3 | ribosomal protein L3 | 0.0267827 |
| RTN4 | reticulon 4 | 0.0267369 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.0266451 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0263264 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0262513 |
| ZNF292 | zinc finger protein 292 | 0.0260422 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0260239 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0259173 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0258042 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0257855 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0257271 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0254746 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0254484 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0249655 |
| RHEB | Ras homolog enriched in brain | 0.0248063 |
| CTPS1 | CTP synthase 1 | 0.0241491 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0240517 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0239308 |
| PAPOLA | poly(A) polymerase alpha | 0.0237835 |
| FLNB | filamin B, beta | 0.02365 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0236338 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0236012 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023593 |
| SIK3 | SIK family kinase 3 | 0.0235407 |
| NCKAP1 | NCK-associated protein 1 | 0.0233759 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0233698 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0232903 |
| ZFR | zinc finger RNA binding protein | 0.0231068 |
| LCA5 | Leber congenital amaurosis 5 | 0.0228147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.194314 |
| GPC3 | glypican 3 | -0.175063 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.174965 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.168821 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.162557 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.130449 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.123167 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0981119 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0922554 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0900007 |
| PCDH9 | protocadherin 9 | -0.0885801 |
| NTM | neurotrimin | -0.0867172 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0859661 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0843218 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0801258 |
| CADM2 | cell adhesion molecule 2 | -0.0776858 |
| LRRC4C | leucine rich repeat containing 4C | -0.0734311 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0718502 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0689144 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0681572 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0673514 |
| PHIP | pleckstrin homology domain interacting protein | -0.0628114 |
| COL3A1 | collagen, type III, alpha 1 | -0.0591375 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0587426 |
| TENM3 | teneurin transmembrane protein 3 | -0.0577004 |
| CDH19 | cadherin 19, type 2 | -0.053139 |
| RPS8 | ribosomal protein S8 | -0.049283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0491917 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0487392 |
| TENM2 | teneurin transmembrane protein 2 | -0.0478912 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0466071 |
| MEIS2 | Meis homeobox 2 | -0.0453989 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0444869 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0439488 |
| PRELID2 | PRELI domain containing 2 | -0.0438981 |
| PLPP1 | phospholipid phosphatase 1 | -0.0434706 |
| LPIN2 | lipin 2 | -0.0434621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0431289 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0426232 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0421155 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0415562 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414749 |
| RFPL4B | ret finger protein-like 4B | -0.0414477 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0394862 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0394207 |
| NHSL1 | NHS-like 1 | -0.0389273 |
| PCDH7 | protocadherin 7 | -0.0381797 |
| FOXP2 | forkhead box P2 | -0.037479 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0371851 |
| RPS16 | ribosomal protein S16 | -0.0369785 |
| FST | follistatin | -0.0366964 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366876 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.036607 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0359867 |
| RAD51B | RAD51 paralog B | -0.035685 |
| TMSB10 | thymosin beta 10 | -0.0354593 |
| RBM20 | RNA binding motif protein 20 | -0.0354471 |
| TOX | thymocyte selection-associated high mobility group box | -0.0351413 |
| ZNF385D | zinc finger protein 385D | -0.034356 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0337946 |
| SNX6 | sorting nexin 6 | -0.0336303 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331738 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0331403 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0327642 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0326659 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0325342 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0318698 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0314773 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0312605 |
| MAP4 | microtubule-associated protein 4 | -0.0311779 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0310053 |
| COL1A2 | collagen, type I, alpha 2 | -0.0309467 |
| MED12L | mediator complex subunit 12-like | -0.030931 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0303262 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0302753 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0302117 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0301281 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0301155 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0301149 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0299861 |
| TRIM2 | tripartite motif containing 2 | -0.0296813 |
| THOC2 | THO complex 2 | -0.0296033 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0293101 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0292409 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0292197 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0290204 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.028989 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0288152 |
| RPLP0 | ribosomal protein, large, P0 | -0.0286698 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0285721 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285201 |
| GRM1 | glutamate receptor, metabotropic 1 | -0.0282969 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0280491 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0278771 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0278479 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0276132 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0274889 |
| PRTG | protogenin | -0.0271629 |
| GLI3 | GLI family zinc finger 3 | -0.0267992 |
