| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0706053 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0617802 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0567937 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0525362 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0524195 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0515343 |
| MKI67 | marker of proliferation Ki-67 | 0.0501201 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0495787 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0492535 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0460721 |
| SPAG9 | sperm associated antigen 9 | 0.0454511 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.036582 |
| ANLN | anillin, actin binding protein | 0.0346454 |
| CENPF | centromere protein F, 350/400kDa | 0.0332319 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0316313 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0311164 |
| ADM | adrenomedullin | 0.0300886 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.028841 |
| FLNA | filamin A, alpha | 0.0283796 |
| DIAPH3 | diaphanous-related formin 3 | 0.0281361 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0276343 |
| FN1 | fibronectin 1 | 0.027551 |
| UBC | ubiquitin C | 0.0274699 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0268767 |
| NAV2 | neuron navigator 2 | 0.0262249 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0245106 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0236463 |
| ARRDC3 | arrestin domain containing 3 | 0.0234598 |
| OGA | O-GlcNAcase | 0.0231057 |
| MXI1 | MAX interactor 1, dimerization protein | 0.022838 |
| CKAP5 | cytoskeleton associated protein 5 | 0.02269 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0225563 |
| TPX2 | TPX2, microtubule-associated | 0.0225211 |
| TXNRD1 | thioredoxin reductase 1 | 0.0224379 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0214518 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0211998 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0211537 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0201398 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0199349 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0199147 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0196703 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0187749 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0187575 |
| KIF4A | kinesin family member 4A | 0.0186905 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0186821 |
| SET | SET nuclear proto-oncogene | 0.0181486 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0179925 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0177174 |
| TPM3 | tropomyosin 3 | 0.0176586 |
| SERINC1 | serine incorporator 1 | 0.0166316 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0163192 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.016032 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0160225 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0159849 |
| CALR | calreticulin | 0.0156328 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0153438 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0152931 |
| RPL3 | ribosomal protein L3 | 0.0151938 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0150559 |
| CALD1 | caldesmon 1 | 0.0150355 |
| YBX1 | Y box binding protein 1 | 0.0148836 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0147869 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0147857 |
| MSN | moesin | 0.0147592 |
| PHIP | pleckstrin homology domain interacting protein | 0.0147464 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.014697 |
| KLF6 | Kruppel-like factor 6 | 0.0146901 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0140869 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0139189 |
| SDC4 | syndecan 4 | 0.0138296 |
| KIF18A | kinesin family member 18A | 0.013806 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0135982 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0135386 |
| NONO | non-POU domain containing, octamer-binding | 0.0135193 |
| TTK | TTK protein kinase | 0.0130974 |
| ADAR | adenosine deaminase, RNA-specific | 0.0130677 |
| ARF4 | ADP-ribosylation factor 4 | 0.012976 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0128294 |
| GOLGA4 | golgin A4 | 0.0126786 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0126117 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0125942 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0124605 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0124333 |
| CNN3 | calponin 3, acidic | 0.0122394 |
| RPS2 | ribosomal protein S2 | 0.0121876 |
| CDCP1 | CUB domain containing protein 1 | 0.0121504 |
| CCNL1 | cyclin L1 | 0.0120985 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0120388 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0120053 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0119964 |
| NUP58 | nucleoporin 58 | 0.0119833 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0118962 |
| KIF11 | kinesin family member 11 | 0.0118806 |
| RPS12 | ribosomal protein S12 | 0.0118187 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0118023 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0117366 |
| RACK1 | receptor for activated C kinase 1 | 0.011583 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0113736 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0113635 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0112983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.248112 |
| VIM | vimentin | -0.191302 |
| GLIS3 | GLIS family zinc finger 3 | -0.176308 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.172388 |
| COL6A3 | collagen, type VI, alpha 3 | -0.152413 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.146238 |
| PDE10A | phosphodiesterase 10A | -0.13716 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.132623 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.120993 |
| CD44 | CD44 molecule (Indian blood group) | -0.109234 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.105171 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102762 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0926398 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0893531 |
| TNS3 | tensin 3 | -0.0891162 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0861637 |
| HMGA2 | high mobility group AT-hook 2 | -0.0848415 |
| VCAN | versican | -0.0848031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0839706 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0826247 |
| HLA-B | major histocompatibility complex, class I, B | -0.0805005 |
| CDH13 | cadherin 13 | -0.0792362 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0780507 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0769067 |
| VCL | vinculin | -0.0757096 |
| TMSB10 | thymosin beta 10 | -0.0744049 |
| NAV1 | neuron navigator 1 | -0.0701442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0665335 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0610815 |
| RAI14 | retinoic acid induced 14 | -0.0606423 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0605148 |
| NDRG1 | N-myc downstream regulated 1 | -0.0600602 |
| SMAD3 | SMAD family member 3 | -0.0600151 |
| DIAPH2 | diaphanous-related formin 2 | -0.0589121 |
| LDHA | lactate dehydrogenase A | -0.0587516 |
| SEPTIN9 | septin 9 | -0.0583331 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0577964 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.055371 |
| IER3 | immediate early response 3 | -0.0551918 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0549752 |
| VEGFA | vascular endothelial growth factor A | -0.0547628 |
| BICC1 | BicC family RNA binding protein 1 | -0.0523443 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0520426 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0518833 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0516834 |
| EFNA5 | ephrin-A5 | -0.0515835 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0510268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0508674 |
| CTSD | cathepsin D | -0.0507723 |
| MYOF | myoferlin | -0.050302 |
| EGFR | epidermal growth factor receptor | -0.0499934 |
| BNC2 | basonuclin 2 | -0.0490818 |
| ASPH | aspartate beta-hydroxylase | -0.0487469 |
| CADM1 | cell adhesion molecule 1 | -0.0483279 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0482131 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0478241 |
| COL5A1 | collagen, type V, alpha 1 | -0.0473897 |
| HLA-A | major histocompatibility complex, class I, A | -0.0472275 |
| SMYD3 | SET and MYND domain containing 3 | -0.0465848 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.046131 |
| ATXN1 | ataxin 1 | -0.0455238 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0447922 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0446854 |
| FAM20C | family with sequence similarity 20, member C | -0.0442511 |
| FTL | ferritin, light polypeptide | -0.0441348 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0440929 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0439621 |
| INTS6 | integrator complex subunit 6 | -0.043656 |
| HDAC9 | histone deacetylase 9 | -0.0433217 |
| RAD51B | RAD51 paralog B | -0.0430098 |
| SLC35F3 | solute carrier family 35, member F3 | -0.042567 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0421636 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0417302 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0417264 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0410401 |
| FBXO11 | F-box protein 11 | -0.0397847 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0397721 |
| TENM2 | teneurin transmembrane protein 2 | -0.0396576 |
| PRKCA | protein kinase C, alpha | -0.0395937 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0394519 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392021 |
| TMEM132D | transmembrane protein 132D | -0.0390471 |
| EGR1 | early growth response 1 | -0.0384149 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0382414 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0381203 |
| PGK1 | phosphoglycerate kinase 1 | -0.0377787 |
| GPC6 | glypican 6 | -0.036023 |
| LRRC7 | leucine rich repeat containing 7 | -0.0356241 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0354559 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0353945 |
| PRR16 | proline rich 16 | -0.0347211 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0346224 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0342005 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0341655 |
| RNF213 | ring finger protein 213 | -0.034016 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0339944 |
| PHF21A | PHD finger protein 21A | -0.0338685 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0337124 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0336658 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0333832 |
