| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Daptomycin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.125999 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.112205 |
| MKI67 | marker of proliferation Ki-67 | 0.0860731 |
| CENPF | centromere protein F, 350/400kDa | 0.0844415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.077865 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0654205 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.064337 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0637251 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0589358 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.052719 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0501887 |
| PTMA | prothymosin, alpha | 0.0461575 |
| SGO2 | shugoshin 2 | 0.0441194 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.043631 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0432889 |
| SET | SET nuclear proto-oncogene | 0.0429156 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0425833 |
| FLNA | filamin A, alpha | 0.0422342 |
| PRELID2 | PRELI domain containing 2 | 0.0422202 |
| TPX2 | TPX2, microtubule-associated | 0.0410486 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0401782 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0387106 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0382372 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.037905 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0378029 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0370855 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0360902 |
| CALU | calumenin | 0.0351656 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0349226 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0347996 |
| UBC | ubiquitin C | 0.0345517 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0341085 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330107 |
| H1-4 | H1.4 linker histone, cluster member | 0.0325625 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0324925 |
| RPL4 | ribosomal protein L4 | 0.0322573 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.031907 |
| CANX | calnexin | 0.0316608 |
| SPAG9 | sperm associated antigen 9 | 0.0313281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0312846 |
| RPL32 | ribosomal protein L32 | 0.0312316 |
| KIF5B | kinesin family member 5B | 0.0311759 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.030918 |
| RPS6 | ribosomal protein S6 | 0.0307124 |
| CPNE1 | copine I | 0.0300537 |
| MCL1 | myeloid cell leukemia 1 | 0.0295464 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0292177 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0289156 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0288009 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0286195 |
| COG5 | component of oligomeric golgi complex 5 | 0.0284121 |
| GPR107 | G protein-coupled receptor 107 | 0.027896 |
| GOLGB1 | golgin B1 | 0.0276669 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.02726 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268791 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0266797 |
| ZNF292 | zinc finger protein 292 | 0.0264089 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0261722 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0261034 |
| FANCD2 | Fanconi anemia, complementation group D2 | 0.0261022 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0259625 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0257923 |
| PANX1 | pannexin 1 | 0.0254883 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0254444 |
| CEP192 | centrosomal protein 192kDa | 0.0253472 |
| GOLGA4 | golgin A4 | 0.0252367 |
| DEK | DEK proto-oncogene | 0.0250567 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0250555 |
| OGA | O-GlcNAcase | 0.0245974 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0244511 |
| SAMD8 | sterile alpha motif domain containing 8 | 0.0244196 |
| KIF23 | kinesin family member 23 | 0.0243059 |
| SEPTIN10 | septin 10 | 0.0241234 |
| DIAPH3 | diaphanous-related formin 3 | 0.0240945 |
| PDS5B | PDS5 cohesin associated factor B | 0.024067 |
| ANXA1 | annexin A1 | 0.0237753 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0237122 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0236394 |
| CEP250 | centrosomal protein 250kDa | 0.0236155 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0235202 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.0233626 |
| TMF1 | TATA element modulatory factor 1 | 0.0231546 |
| SIK3 | SIK family kinase 3 | 0.0229804 |
| FANCC | Fanconi anemia, complementation group C | 0.0229689 |
| RPL5 | ribosomal protein L5 | 0.0229461 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0229176 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0228389 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0228274 |
| TPM3 | tropomyosin 3 | 0.0227684 |
| SSH2 | slingshot protein phosphatase 2 | 0.0224949 |
| NONO | non-POU domain containing, octamer-binding | 0.0223764 |
| SP3 | Sp3 transcription factor | 0.0223666 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0223569 |
| USP47 | ubiquitin specific peptidase 47 | 0.022176 |
| KIF20B | kinesin family member 20B | 0.0221444 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0221118 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0220304 |
| TMPO | thymopoietin | 0.0220118 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0219673 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0219534 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.141398 |
| TMSB10 | thymosin beta 10 | -0.112705 |
| FNDC3B | fibronectin type III domain containing 3B | -0.100128 |
| LDHA | lactate dehydrogenase A | -0.0881841 |
| RIGI | RNA sensor RIG-I | -0.0821873 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.073302 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0726243 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0658477 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0656798 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0648425 |
| MT2A | metallothionein 2A | -0.0601802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0572348 |
| ANGPTL4 | angiopoietin-like 4 | -0.0557091 |
| ATXN1 | ataxin 1 | -0.0543324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0530016 |
| PRR16 | proline rich 16 | -0.0517766 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0504954 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.050012 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0494155 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0490931 |
| DST | dystonin | -0.0485738 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0484474 |
| RPLP1 | ribosomal protein, large, P1 | -0.0478802 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0463838 |
| AHNAK | AHNAK nucleoprotein | -0.0458319 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0447001 |
| GPC6 | glypican 6 | -0.0439141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0419752 |
| PKM | pyruvate kinase, muscle | -0.0414748 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0413243 |
| EGR1 | early growth response 1 | -0.0410715 |
| PYGL | phosphorylase, glycogen, liver | -0.039949 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0398758 |
| DENND5B | DENN/MADD domain containing 5B | -0.0394748 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0393523 |
| HMGA2 | high mobility group AT-hook 2 | -0.0388798 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0383652 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0371831 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0370825 |
| MYO9B | myosin IXB | -0.0369481 |
| SVIL | supervillin | -0.035866 |
| PCED1B | PC-esterase domain containing 1B | -0.03564 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0352351 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0351967 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0349347 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0345352 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0341897 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0341365 |
| SMAP1 | small ArfGAP 1 | -0.0338602 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0335875 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0335182 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0328715 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.031916 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0318917 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0318799 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0318446 |
| MED13 | mediator complex subunit 13 | -0.0317071 |
| PRSS23 | protease, serine, 23 | -0.0316379 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0313049 |
| NALCN | sodium leak channel, non selective | -0.0297732 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0294149 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0291483 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.029135 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0290324 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.028414 |
| RPL35A | ribosomal protein L35a | -0.0282042 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0281077 |
| RNF213 | ring finger protein 213 | -0.0280085 |
| IGF2 | insulin-like growth factor 2 | -0.027848 |
| B2M | beta-2-microglobulin | -0.0277155 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0276775 |
| ATG7 | autophagy related 7 | -0.0276455 |
| FMNL2 | formin-like 2 | -0.0273935 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0273893 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0271392 |
| EGFR | epidermal growth factor receptor | -0.0270065 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0267981 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0267409 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0267253 |
| LAMA5 | laminin, alpha 5 | -0.0264073 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0263644 |
| GNAS | GNAS complex locus | -0.0262279 |
| KIAA1549L | KIAA1549-like | -0.0259966 |
| DTNA | dystrobrevin, alpha | -0.0259844 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0259637 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0257033 |
| RAI14 | retinoic acid induced 14 | -0.0255396 |
| FTL | ferritin, light polypeptide | -0.0255156 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0255082 |
| VIM | vimentin | -0.0254975 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0254875 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0254475 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0251493 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0251177 |
| MYOF | myoferlin | -0.0251074 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0248443 |
| ANXA2 | annexin A2 | -0.0247385 |
| HLA-A | major histocompatibility complex, class I, A | -0.0247117 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.024638 |
| TUT7 | terminal uridylyl transferase 7 | -0.0244948 |
