| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Daptomycin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Daptomycin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.140939 |
| CENPF | centromere protein F, 350/400kDa | 0.13418 |
| MKI67 | marker of proliferation Ki-67 | 0.115713 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0705985 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0651072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0648366 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0561747 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0538542 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0509872 |
| ANLN | anillin, actin binding protein | 0.04783 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0460381 |
| RACK1 | receptor for activated C kinase 1 | 0.0454209 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0450441 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0441514 |
| TXNRD1 | thioredoxin reductase 1 | 0.0436723 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0432077 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0429783 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0427121 |
| RPS6 | ribosomal protein S6 | 0.0420437 |
| OGA | O-GlcNAcase | 0.0409878 |
| FLNA | filamin A, alpha | 0.0401201 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0389228 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0374849 |
| HDGF | hepatoma-derived growth factor | 0.0368031 |
| CENPE | centromere protein E, 312kDa | 0.0365164 |
| TPX2 | TPX2, microtubule-associated | 0.036396 |
| CANX | calnexin | 0.034978 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0347543 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0346299 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0345201 |
| KIF14 | kinesin family member 14 | 0.0343695 |
| KIF5B | kinesin family member 5B | 0.0339971 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0324645 |
| NUP58 | nucleoporin 58 | 0.0312881 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0311215 |
| RNF145 | ring finger protein 145 | 0.0309702 |
| TPM3 | tropomyosin 3 | 0.0308367 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0307766 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0307187 |
| NEK7 | NIMA-related kinase 7 | 0.0303521 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0297183 |
| SGO2 | shugoshin 2 | 0.0292549 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0290996 |
| PAPOLA | poly(A) polymerase alpha | 0.0286576 |
| GOLGA4 | golgin A4 | 0.0286199 |
| RBM25 | RNA binding motif protein 25 | 0.0282709 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0278553 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0277651 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0274922 |
| CALR | calreticulin | 0.0270025 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0266391 |
| NCKAP1 | NCK-associated protein 1 | 0.0264348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0263774 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0259745 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0253763 |
| XPO1 | exportin 1 | 0.0253552 |
| SLTM | SAFB-like, transcription modulator | 0.025301 |
| TPR | translocated promoter region, nuclear basket protein | 0.0252376 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0244336 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0243147 |
| RPS12 | ribosomal protein S12 | 0.0242762 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0242187 |
| WDR45B | WD repeat domain 45B | 0.0238278 |
| AHR | aryl hydrocarbon receptor | 0.0237776 |
| ZFR | zinc finger RNA binding protein | 0.0236165 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0232484 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.022951 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0229066 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0228527 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0227878 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0223943 |
| OSMR | oncostatin M receptor | 0.0223082 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0221649 |
| PRR11 | proline rich 11 | 0.0219918 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0218097 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0217925 |
| SPAG9 | sperm associated antigen 9 | 0.0214717 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0214123 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0214049 |
| FBXO32 | F-box protein 32 | 0.0213491 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0212649 |
| KIF11 | kinesin family member 11 | 0.0211347 |
| PHIP | pleckstrin homology domain interacting protein | 0.0206648 |
| FNBP1 | formin binding protein 1 | 0.0206259 |
| OTUD7B | OTU deubiquitinase 7B | 0.0205576 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0204848 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0203673 |
| PNN | pinin, desmosome associated protein | 0.020314 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0202623 |
| ZNF292 | zinc finger protein 292 | 0.0202461 |
| RPS2 | ribosomal protein S2 | 0.0201519 |
| CEP192 | centrosomal protein 192kDa | 0.0198501 |
| EREG | epiregulin | 0.019785 |
| SUCO | SUN domain containing ossification factor | 0.0197712 |
| CCNB1 | cyclin B1 | 0.0197331 |
| RBM39 | RNA binding motif protein 39 | 0.0197233 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0196473 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0196385 |
| MATR3 | matrin 3 | 0.0196172 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0193999 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.342247 |
| NRG1 | neuregulin 1 | -0.333488 |
| HMGA2 | high mobility group AT-hook 2 | -0.16534 |
| ASPH | aspartate beta-hydroxylase | -0.127481 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0929221 |
| GLIS3 | GLIS family zinc finger 3 | -0.0865279 |
| EFNA5 | ephrin-A5 | -0.0834864 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0789796 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0756967 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0736557 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.073332 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0724654 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0718549 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.071709 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0704603 |
| SQSTM1 | sequestosome 1 | -0.0691669 |
| RAI14 | retinoic acid induced 14 | -0.0645766 |
| PLIN2 | perilipin 2 | -0.0629878 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.061757 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0616764 |
| VCL | vinculin | -0.0613183 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0598397 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0596197 |
| INTS6 | integrator complex subunit 6 | -0.0585574 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0585318 |
| TMSB10 | thymosin beta 10 | -0.0571453 |
| AEBP2 | AE binding protein 2 | -0.0563312 |
| NDRG1 | N-myc downstream regulated 1 | -0.0535529 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.050132 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0476953 |
| SYT1 | synaptotagmin I | -0.0470029 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0468576 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0466955 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0441435 |
| HLA-B | major histocompatibility complex, class I, B | -0.04339 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0416057 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0409953 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0401213 |
| ITGA1 | integrin, alpha 1 | -0.0400714 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.039815 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0387225 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0385894 |
| GPC6 | glypican 6 | -0.0383263 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0378958 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0377675 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0371089 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0368327 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0368093 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0365396 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0356622 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0355146 |
| TENM4 | teneurin transmembrane protein 4 | -0.0353295 |
| LOXL2 | lysyl oxidase-like 2 | -0.0353291 |
| RASAL2 | RAS protein activator like 2 | -0.0350029 |
| CADM1 | cell adhesion molecule 1 | -0.0347515 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0344088 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0341935 |
| RAD51B | RAD51 paralog B | -0.0340585 |
| PRKCA | protein kinase C, alpha | -0.0334917 |
| TNS3 | tensin 3 | -0.0330982 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.032613 |
| POTEF | POTE ankyrin domain family, member F | -0.0322676 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0318014 |
| HMGA1 | high mobility group AT-hook 1 | -0.0317568 |
| PALLD | palladin, cytoskeletal associated protein | -0.0316307 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0315021 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0310756 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0308016 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0305697 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0304901 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0303909 |
| TMEM165 | transmembrane protein 165 | -0.0302266 |
| ACTG1 | actin gamma 1 | -0.0295665 |
| OXR1 | oxidation resistance 1 | -0.0294721 |
| LRRC23 | leucine rich repeat containing 23 | -0.0294259 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0288136 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0287841 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0287295 |
| S100A6 | S100 calcium binding protein A6 | -0.0286828 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0283731 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.027968 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0275848 |
| CTBP2 | C-terminal binding protein 2 | -0.0273601 |
| TGFA | transforming growth factor, alpha | -0.0273362 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0273335 |
| FTL | ferritin, light polypeptide | -0.0267706 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0264137 |
| GPATCH2L | G patch domain containing 2-like | -0.0261862 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0259726 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0252362 |
| GLUL | glutamate-ammonia ligase | -0.0251041 |
| EGR1 | early growth response 1 | -0.0249983 |
| TGFB1 | transforming growth factor, beta 1 | -0.0247362 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0245053 |
| AOPEP | aminopeptidase O (putative) | -0.0242506 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0241874 |
| NPAS2 | neuronal PAS domain protein 2 | -0.024124 |
| NTN4 | netrin 4 | -0.0240041 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.023922 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0238717 |
