| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.152045 |
| TLE4 | transducin-like enhancer of split 4 | 0.0928851 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0718799 |
| FMN1 | formin 1 | 0.0697437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0652098 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0628882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0600071 |
| LSAMP | limbic system-associated membrane protein | 0.0508567 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.04508 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.045056 |
| TPM1 | tropomyosin 1 (alpha) | 0.0414096 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.039364 |
| GLCCI1 | glucocorticoid induced 1 | 0.0368282 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353796 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0351821 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0344761 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0327167 |
| TRIB2 | tribbles pseudokinase 2 | 0.0321579 |
| PDE10A | phosphodiesterase 10A | 0.0316996 |
| THBS1 | thrombospondin 1 | 0.0310129 |
| PLPP1 | phospholipid phosphatase 1 | 0.0308396 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303633 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0300886 |
| ACTG1 | actin gamma 1 | 0.0298885 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0293861 |
| STK38L | serine/threonine kinase 38 like | 0.0290235 |
| KLHL13 | kelch-like family member 13 | 0.0290013 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0278698 |
| MRTFA | myocardin related transcription factor A | 0.0278082 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0276822 |
| SIK2 | salt-inducible kinase 2 | 0.0275766 |
| TENM4 | teneurin transmembrane protein 4 | 0.0266993 |
| PCBP3 | poly(rC) binding protein 3 | 0.0265768 |
| FAM107B | family with sequence similarity 107, member B | 0.0262805 |
| VMP1 | vacuole membrane protein 1 | 0.0260328 |
| HOMER1 | homer scaffolding protein 1 | 0.0260283 |
| RNF213 | ring finger protein 213 | 0.025255 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0251878 |
| AHNAK | AHNAK nucleoprotein | 0.0249098 |
| ANTXR1 | anthrax toxin receptor 1 | 0.024807 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0233426 |
| FERMT2 | fermitin family member 2 | 0.0231837 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0224352 |
| MYO1E | myosin IE | 0.0224349 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0224112 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0222488 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0213264 |
| INTS6 | integrator complex subunit 6 | 0.0211821 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0211031 |
| MED13 | mediator complex subunit 13 | 0.0205079 |
| RIGI | RNA sensor RIG-I | 0.0203863 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0202809 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0200945 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0193332 |
| AMOTL1 | angiomotin like 1 | 0.0192339 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191206 |
| IRS1 | insulin receptor substrate 1 | 0.0188403 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0188039 |
| ACTN1 | actinin, alpha 1 | 0.0185306 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0183677 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0182068 |
| TPM4 | tropomyosin 4 | 0.0181637 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0177341 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0175652 |
| RPL4 | ribosomal protein L4 | 0.0171223 |
| SQSTM1 | sequestosome 1 | 0.0169869 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0165796 |
| KLF6 | Kruppel-like factor 6 | 0.0164857 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0164498 |
| LPIN1 | lipin 1 | 0.0161126 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0160564 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0159686 |
| MYO6 | myosin VI | 0.0159332 |
| SMAD3 | SMAD family member 3 | 0.0158944 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0158651 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0158401 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0157729 |
| PRKCA | protein kinase C, alpha | 0.0157635 |
| GSE1 | Gse1 coiled-coil protein | 0.0157059 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0154769 |
| DNM3 | dynamin 3 | 0.0153455 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0153058 |
| CUL3 | cullin 3 | 0.0152803 |
| PALLD | palladin, cytoskeletal associated protein | 0.015254 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0151905 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0151774 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.015174 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0151382 |
| ASPH | aspartate beta-hydroxylase | 0.0151138 |
| RPL23 | ribosomal protein L23 | 0.0150495 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0150302 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0149885 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0149846 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0149491 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0149421 |
| SET | SET nuclear proto-oncogene | 0.014932 |
| PARD3 | par-3 family cell polarity regulator | 0.0149045 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0147656 |
| SYNPO2 | synaptopodin 2 | 0.0146639 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.014607 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.462141 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.220803 |
| NRG1 | neuregulin 1 | -0.104258 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0703809 |
| NDRG1 | N-myc downstream regulated 1 | -0.0601685 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0601413 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0594784 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.058148 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0577932 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.056719 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0487839 |
| MAP1B | microtubule-associated protein 1B | -0.0463783 |
| GPC5 | glypican 5 | -0.0455625 |
| MEF2A | myocyte enhancer factor 2A | -0.0435592 |
| GDF15 | growth differentiation factor 15 | -0.0434737 |
| GOLGA4 | golgin A4 | -0.0431624 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0423931 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0409979 |
| SYT1 | synaptotagmin I | -0.040787 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0406145 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0394186 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0388499 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378503 |
| ZNF292 | zinc finger protein 292 | -0.0350414 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0327855 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0320488 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0309764 |
| WDR45B | WD repeat domain 45B | -0.0302595 |
| COPA | coatomer protein complex, subunit alpha | -0.0298158 |
| STC1 | stanniocalcin 1 | -0.0296011 |
| USP34 | ubiquitin specific peptidase 34 | -0.0281389 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0280628 |
| CADM2 | cell adhesion molecule 2 | -0.0276492 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.026728 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0257355 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0251781 |
| ZNF148 | zinc finger protein 148 | -0.025059 |
| HELZ | helicase with zinc finger | -0.0249227 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0246682 |
| FAM13A | family with sequence similarity 13, member A | -0.0245416 |
| SETD5 | SET domain containing 5 | -0.0244635 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0242741 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0242671 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0241342 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0237629 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0237064 |
| DPH6 | diphthamine biosynthesis 6 | -0.0236823 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231853 |
| RTN4 | reticulon 4 | -0.0228304 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0224448 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0223785 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0220935 |
| MTSS2 | MTSS I-BAR domain containing 2 | -0.022031 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0217218 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0215471 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0214221 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.021274 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0204764 |
| CENPF | centromere protein F, 350/400kDa | -0.0202693 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.020147 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.020024 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0199674 |
| SRP54 | signal recognition particle 54kDa | -0.0198747 |
| RHOA | ras homolog family member A | -0.0194529 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0192332 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0189215 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0188793 |
| PRTG | protogenin | -0.0185376 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0184226 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0183236 |
| PTMA | prothymosin, alpha | -0.0182652 |
| FNBP1 | formin binding protein 1 | -0.0182551 |
| NUP58 | nucleoporin 58 | -0.0181345 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0180983 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0180789 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.018023 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0179425 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0179262 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0175818 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0175392 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0174151 |
| USP3 | ubiquitin specific peptidase 3 | -0.0173324 |
| YEATS2 | YEATS domain containing 2 | -0.0172724 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0172695 |
| SLC39A11 | solute carrier family 39, member 11 | -0.017238 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0171462 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0170872 |
| ANGPT1 | angiopoietin 1 | -0.0170062 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0168595 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0167714 |
| CBX3 | chromobox homolog 3 | -0.0165987 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0164221 |
| SMC4 | structural maintenance of chromosomes 4 | -0.016178 |
| SEPTIN2 | septin 2 | -0.0160728 |
| HMGA1 | high mobility group AT-hook 1 | -0.0160603 |
| NBAS | neuroblastoma amplified sequence | -0.0160572 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0158805 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0158529 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0157803 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0157435 |
