| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0691854 |
| TMSB10 | thymosin beta 10 | 0.0564134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0556516 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0541813 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0521607 |
| VCL | vinculin | 0.0432301 |
| RPS12 | ribosomal protein S12 | 0.0416656 |
| INTS6 | integrator complex subunit 6 | 0.0377903 |
| B2M | beta-2-microglobulin | 0.0362341 |
| RPS3 | ribosomal protein S3 | 0.0352808 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0322936 |
| MSN | moesin | 0.0315393 |
| BCL2L1 | BCL2-like 1 | 0.0248867 |
| RPS19 | ribosomal protein S19 | 0.02371 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0234807 |
| BRD2 | bromodomain containing 2 | 0.0227893 |
| CLU | clusterin | 0.0216414 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0215987 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0215972 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0214707 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0210025 |
| PTMA | prothymosin, alpha | 0.020918 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0206492 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0205013 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0202767 |
| CORO2A | coronin, actin binding protein, 2A | 0.0201763 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.020156 |
| FNDC3B | fibronectin type III domain containing 3B | 0.019948 |
| CALR | calreticulin | 0.0199269 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0199023 |
| ANGPTL4 | angiopoietin-like 4 | 0.0196811 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0194579 |
| MCL1 | myeloid cell leukemia 1 | 0.0192682 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0191573 |
| SFTPA2 | surfactant protein A2 | 0.018973 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0189688 |
| RPL23 | ribosomal protein L23 | 0.0186598 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0185238 |
| RPL37A | ribosomal protein L37a | 0.0181546 |
| RPS17 | ribosomal protein S17 | 0.0180215 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0179604 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0179104 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0178642 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0178024 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0176253 |
| TNS4 | tensin 4 | 0.0174203 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0174133 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173461 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0170148 |
| ANKRD12 | ankyrin repeat domain 12 | 0.016978 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0166539 |
| RPS2 | ribosomal protein S2 | 0.016115 |
| NUCB2 | nucleobindin 2 | 0.0160695 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0159689 |
| LUZP1 | leucine zipper protein 1 | 0.0159615 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.015764 |
| COG5 | component of oligomeric golgi complex 5 | 0.0157619 |
| SETX | senataxin | 0.0157353 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0157215 |
| RNF145 | ring finger protein 145 | 0.0157079 |
| CHMP5 | charged multivesicular body protein 5 | 0.0156417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155454 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0155265 |
| YTHDC1 | YTH domain containing 1 | 0.0155233 |
| KRT17 | keratin 17, type I | 0.0154546 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0154194 |
| MGP | matrix Gla protein | 0.0153372 |
| USO1 | USO1 vesicle transport factor | 0.0153042 |
| CUL3 | cullin 3 | 0.0152812 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0151506 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.015114 |
| KRT6A | keratin 6A, type II | 0.015014 |
| RPL21 | ribosomal protein L21 | 0.0150042 |
| TOP1 | topoisomerase (DNA) I | 0.0149575 |
| METTL15 | methyltransferase like 15 | 0.0149125 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0148192 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0147918 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0147367 |
| STC1 | stanniocalcin 1 | 0.0147026 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0145783 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0145193 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0145026 |
| RPL9 | ribosomal protein L9 | 0.0143759 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0142207 |
| YBX3 | Y box binding protein 3 | 0.0142134 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0141399 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0140278 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0140218 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0139812 |
| NBEA | neurobeachin | 0.0139402 |
| MIDN | midnolin | 0.0139087 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0138971 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0137348 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0136121 |
| ATF4 | activating transcription factor 4 | 0.0135866 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0135309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0135238 |
| PSEN1 | presenilin 1 | 0.0135096 |
| DUSP4 | dual specificity phosphatase 4 | 0.0134808 |
| FRMD8 | FERM domain containing 8 | 0.0134588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.246799 |
| MTSS1 | metastasis suppressor 1 | -0.225462 |
| RAI14 | retinoic acid induced 14 | -0.131156 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.116762 |
| CD44 | CD44 molecule (Indian blood group) | -0.0984065 |
| SULF1 | sulfatase 1 | -0.0975179 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0822539 |
| AHNAK | AHNAK nucleoprotein | -0.0817148 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0794681 |
| S100A10 | S100 calcium binding protein A10 | -0.0749297 |
| PODXL | podocalyxin-like | -0.0743654 |
| NAV2 | neuron navigator 2 | -0.0742899 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0732635 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0724633 |
| MEF2A | myocyte enhancer factor 2A | -0.072125 |
| SLC35F3 | solute carrier family 35, member F3 | -0.064762 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0615132 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.061428 |
| LAMC2 | laminin, gamma 2 | -0.058682 |
| EMP1 | epithelial membrane protein 1 | -0.057151 |
| MKI67 | marker of proliferation Ki-67 | -0.0558694 |
| ANXA2 | annexin A2 | -0.0556616 |
| PGK1 | phosphoglycerate kinase 1 | -0.0549119 |
| DOK5 | docking protein 5 | -0.0536253 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0530706 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0516132 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.051407 |
| SULF2 | sulfatase 2 | -0.050963 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0492804 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0484605 |
| CALB1 | calbindin 1, 28kDa | -0.0475132 |
| TPM4 | tropomyosin 4 | -0.0470625 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0458251 |
| CDK6 | cyclin-dependent kinase 6 | -0.0456394 |
| LDHA | lactate dehydrogenase A | -0.0443837 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0439788 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0438052 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0435743 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0431414 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0428193 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.042682 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0426129 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0416728 |
| MYOF | myoferlin | -0.0406285 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.040532 |
| TNS3 | tensin 3 | -0.0400341 |
| RIGI | RNA sensor RIG-I | -0.0398214 |
| OSMR | oncostatin M receptor | -0.0396413 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0388104 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0385225 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0377885 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0375328 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0369102 |
| NDRG1 | N-myc downstream regulated 1 | -0.0366546 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0361507 |
| PTK2 | protein tyrosine kinase 2 | -0.0359521 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0356172 |
| FN1 | fibronectin 1 | -0.0353853 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0347896 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0345273 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.033626 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0327515 |
| ENO1 | enolase 1, (alpha) | -0.0326438 |
| PLS3 | plastin 3 | -0.0324538 |
| MYO10 | myosin X | -0.0323644 |
| XPO1 | exportin 1 | -0.0323328 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0320232 |
| RNF217 | ring finger protein 217 | -0.0318367 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0314044 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0308127 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0307956 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0305028 |
| CDCP1 | CUB domain containing protein 1 | -0.030358 |
| CUX1 | cut-like homeobox 1 | -0.030338 |
| ACTN4 | actinin, alpha 4 | -0.029808 |
| TXNRD1 | thioredoxin reductase 1 | -0.0296028 |
| IGF2 | insulin-like growth factor 2 | -0.0293934 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0293759 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0292241 |
| SMYD3 | SET and MYND domain containing 3 | -0.0286159 |
| RAD51B | RAD51 paralog B | -0.0285023 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0284154 |
| TMSB4X | thymosin beta 4, X-linked | -0.0283334 |
| HMGA2 | high mobility group AT-hook 2 | -0.0270804 |
| ASPH | aspartate beta-hydroxylase | -0.027032 |
| HLA-E | major histocompatibility complex, class I, E | -0.0269419 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0267338 |
| UBC | ubiquitin C | -0.0265661 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0264302 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0260271 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0257277 |
| LDLR | low density lipoprotein receptor | -0.0254878 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0252251 |
| UTRN | utrophin | -0.0251167 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0251058 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0250188 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0249516 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0248788 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248398 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0248248 |
