| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.137312 |
| LMO7 | LIM domain 7 | 0.117952 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.10354 |
| MYO1E | myosin IE | 0.0949981 |
| MT2A | metallothionein 2A | 0.0775224 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0761352 |
| FAT1 | FAT atypical cadherin 1 | 0.072069 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0700411 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0654996 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0622013 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0544961 |
| EZR | ezrin | 0.0544601 |
| ASPH | aspartate beta-hydroxylase | 0.0539558 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0498824 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0496917 |
| AHNAK | AHNAK nucleoprotein | 0.049195 |
| EGFR | epidermal growth factor receptor | 0.0489652 |
| EMP1 | epithelial membrane protein 1 | 0.0481169 |
| ITGA6 | integrin, alpha 6 | 0.0468133 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0463268 |
| ACTG1 | actin gamma 1 | 0.0430434 |
| RPL7A | ribosomal protein L7a | 0.0428674 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0427439 |
| LAMA4 | laminin, alpha 4 | 0.0427242 |
| SVIL | supervillin | 0.0421366 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0413657 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0399765 |
| ANXA1 | annexin A1 | 0.0397664 |
| DSPP | dentin sialophosphoprotein | 0.0397261 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.039164 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0388851 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0385644 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0369067 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0364351 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0348982 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0347438 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0342902 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0341006 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0340063 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0334594 |
| MT1E | metallothionein 1E | 0.0330339 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0324943 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0320801 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0320508 |
| MT1X | metallothionein 1X | 0.0319321 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0319031 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313619 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0308362 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0307694 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0301718 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.030107 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0298679 |
| RIGI | RNA sensor RIG-I | 0.0297439 |
| CLOCK | clock circadian regulator | 0.0293951 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0293044 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0291052 |
| PIGR | polymeric immunoglobulin receptor | 0.0288578 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0284536 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0284173 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0280779 |
| POF1B | premature ovarian failure, 1B | 0.0269598 |
| RPL19 | ribosomal protein L19 | 0.0263198 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0262373 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261545 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0258367 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0257822 |
| PDLIM5 | PDZ and LIM domain 5 | 0.025649 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0254684 |
| INTS6 | integrator complex subunit 6 | 0.0248891 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0245523 |
| RPS29 | ribosomal protein S29 | 0.0245492 |
| TJP1 | tight junction protein 1 | 0.0240329 |
| PLEC | plectin | 0.0236001 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0235857 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0235312 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0235129 |
| CALR | calreticulin | 0.0234961 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0234305 |
| RNF217 | ring finger protein 217 | 0.023374 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0229939 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0229607 |
| MUC13 | mucin 13, cell surface associated | 0.0228909 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0227356 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.02267 |
| RPL34 | ribosomal protein L34 | 0.0226534 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0226068 |
| DUSP16 | dual specificity phosphatase 16 | 0.0226058 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0225668 |
| FHIT | fragile histidine triad | 0.0224486 |
| LDHA | lactate dehydrogenase A | 0.0220278 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0219701 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0218565 |
| UBN2 | ubinuclein 2 | 0.0218461 |
| H1-4 | H1.4 linker histone, cluster member | 0.0216944 |
| CDK13 | cyclin-dependent kinase 13 | 0.0216527 |
| ENO1 | enolase 1, (alpha) | 0.0213461 |
| AHI1 | Abelson helper integration site 1 | 0.0213189 |
| AEBP2 | AE binding protein 2 | 0.0211995 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.021138 |
| LAMC2 | laminin, gamma 2 | 0.021117 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.171596 |
| PTMA | prothymosin, alpha | -0.127943 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.123749 |
| TNS4 | tensin 4 | -0.114354 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.103681 |
| RNF43 | ring finger protein 43 | -0.0890972 |
| NDRG1 | N-myc downstream regulated 1 | -0.0879614 |
| GOLGA4 | golgin A4 | -0.081642 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0782818 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0771699 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0764142 |
| CD46 | CD46 molecule, complement regulatory protein | -0.074284 |
| ANXA2 | annexin A2 | -0.073908 |
| ZNF292 | zinc finger protein 292 | -0.0722182 |
| EREG | epiregulin | -0.0649962 |
| HMGA1 | high mobility group AT-hook 1 | -0.0622363 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0589867 |
| TRIM2 | tripartite motif containing 2 | -0.0586765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0548375 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0546468 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0534242 |
| SETD5 | SET domain containing 5 | -0.0531886 |
| FOSL1 | FOS-like antigen 1 | -0.0531169 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0524402 |
| MED13L | mediator complex subunit 13-like | -0.0517821 |
| RBM39 | RNA binding motif protein 39 | -0.050805 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.050231 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0501133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0499311 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0497398 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0490352 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0489692 |
| COG5 | component of oligomeric golgi complex 5 | -0.0478824 |
| TXNRD1 | thioredoxin reductase 1 | -0.0475527 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0460351 |
| WDR43 | WD repeat domain 43 | -0.0459967 |
| ETNK1 | ethanolamine kinase 1 | -0.0456949 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0446089 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0445196 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0442688 |
| PRSS3 | protease, serine, 3 | -0.0441503 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0437859 |
| POTEF | POTE ankyrin domain family, member F | -0.0429655 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.042553 |
| RNF145 | ring finger protein 145 | -0.0422355 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0421709 |
| ACTN4 | actinin, alpha 4 | -0.0414399 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0412354 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0411888 |
| USP3 | ubiquitin specific peptidase 3 | -0.040936 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0405498 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0405491 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0404686 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0402546 |
| GPHN | gephyrin | -0.0401053 |
| RREB1 | ras responsive element binding protein 1 | -0.0398001 |
| NUP58 | nucleoporin 58 | -0.0396964 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0396638 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0395036 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0393534 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0388845 |
| FAM13A | family with sequence similarity 13, member A | -0.0388105 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0387862 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0387854 |
| YBX1 | Y box binding protein 1 | -0.038778 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0386777 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0383358 |
| VEGFA | vascular endothelial growth factor A | -0.0379443 |
| RFX7 | regulatory factor X, 7 | -0.0378816 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0375194 |
| CCNL1 | cyclin L1 | -0.0371414 |
| CENPF | centromere protein F, 350/400kDa | -0.0371127 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.036605 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0364064 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.036369 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0359132 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0354875 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0354496 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0351735 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0350877 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0347258 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0344477 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0344207 |
| RPL23 | ribosomal protein L23 | -0.0341087 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0335336 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0334849 |
| OGA | O-GlcNAcase | -0.03343 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0333938 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0332859 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0332432 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0332411 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0327364 |
| RBM25 | RNA binding motif protein 25 | -0.0325999 |
| MATR3 | matrin 3 | -0.0325147 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0324482 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0323262 |
| PCBP2 | poly(rC) binding protein 2 | -0.0321659 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0320282 |
| NBAS | neuroblastoma amplified sequence | -0.0315608 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0315597 |
