| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Darinaparsin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.205841 |
| PTMA | prothymosin, alpha | 0.130419 |
| TMSB4X | thymosin beta 4, X-linked | 0.129694 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.106159 |
| DST | dystonin | 0.0883857 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0794664 |
| MT2A | metallothionein 2A | 0.0748249 |
| FMNL2 | formin-like 2 | 0.0707432 |
| CAPRIN2 | caprin family member 2 | 0.0701924 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.066301 |
| KLF6 | Kruppel-like factor 6 | 0.0614757 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0574601 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.051346 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0513009 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0495099 |
| TXNIP | thioredoxin interacting protein | 0.049489 |
| RPS8 | ribosomal protein S8 | 0.0490199 |
| FTL | ferritin, light polypeptide | 0.0471457 |
| RPL12 | ribosomal protein L12 | 0.0466043 |
| MT1X | metallothionein 1X | 0.046196 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0453447 |
| PRELID2 | PRELI domain containing 2 | 0.043332 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0424722 |
| VCL | vinculin | 0.0418588 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0390569 |
| SQSTM1 | sequestosome 1 | 0.0383338 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.03749 |
| OGA | O-GlcNAcase | 0.0365819 |
| MT1E | metallothionein 1E | 0.0365789 |
| PGK1 | phosphoglycerate kinase 1 | 0.0364346 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0361321 |
| SDC4 | syndecan 4 | 0.0351505 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.035141 |
| H1-0 | H1.0 linker histone | 0.0349992 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.034918 |
| RPL26 | ribosomal protein L26 | 0.0345484 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0342639 |
| EREG | epiregulin | 0.0341605 |
| AHNAK | AHNAK nucleoprotein | 0.0340896 |
| ANGPTL4 | angiopoietin-like 4 | 0.0337954 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0334608 |
| SPAG9 | sperm associated antigen 9 | 0.0323842 |
| SP100 | SP100 nuclear antigen | 0.0314761 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0313059 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0309686 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0305348 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0301665 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0297419 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.029607 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0295961 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0292643 |
| TPI1 | triosephosphate isomerase 1 | 0.0288578 |
| RPL35A | ribosomal protein L35a | 0.0287681 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0286591 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0276829 |
| RPS12 | ribosomal protein S12 | 0.027472 |
| PLK2 | polo-like kinase 2 | 0.0273917 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0272872 |
| TMSB10 | thymosin beta 10 | 0.0271834 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0266143 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.026403 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0262222 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025604 |
| PLEC | plectin | 0.0255857 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0253282 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0252342 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250512 |
| RPL19 | ribosomal protein L19 | 0.0243247 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0242282 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0237262 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0236904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0235426 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0234557 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0233168 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0233148 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0231122 |
| RPS27A | ribosomal protein S27a | 0.0231117 |
| RPLP1 | ribosomal protein, large, P1 | 0.0230697 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0230077 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0228818 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0225952 |
| RPL13A | ribosomal protein L13a | 0.0222446 |
| RLF | rearranged L-myc fusion | 0.0222325 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0221436 |
| HLA-E | major histocompatibility complex, class I, E | 0.0220812 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0218799 |
| CEP250 | centrosomal protein 250kDa | 0.021796 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.021787 |
| RPL31 | ribosomal protein L31 | 0.0217092 |
| TFRC | transferrin receptor | 0.0214754 |
| RPL7A | ribosomal protein L7a | 0.0209536 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0209182 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0209176 |
| RPL36 | ribosomal protein L36 | 0.0208885 |
| RAD51B | RAD51 paralog B | 0.0207123 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0202509 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0202081 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0201482 |
| ASPH | aspartate beta-hydroxylase | 0.0200681 |
| RIOK3 | RIO kinase 3 | 0.0199832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.248132 |
| POTEF | POTE ankyrin domain family, member F | -0.194029 |
| TXNRD1 | thioredoxin reductase 1 | -0.164055 |
| EGR1 | early growth response 1 | -0.103493 |
| HMGA1 | high mobility group AT-hook 1 | -0.0800433 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0789963 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0762948 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0750579 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0733684 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0664304 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.066383 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0582343 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0581826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.054681 |
| TAPBP | TAP binding protein (tapasin) | -0.0535505 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0526682 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0518253 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0498349 |
| MYADM | myeloid-associated differentiation marker | -0.0491943 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0480512 |
| CENPF | centromere protein F, 350/400kDa | -0.0468563 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0456396 |
| RTN4 | reticulon 4 | -0.0442449 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0430683 |
| VIM | vimentin | -0.0430573 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.042901 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414818 |
| LOXL2 | lysyl oxidase-like 2 | -0.0412558 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.040898 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0405746 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0398006 |
| PCBP2 | poly(rC) binding protein 2 | -0.0393376 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0379885 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0376382 |
| YEATS2 | YEATS domain containing 2 | -0.0375664 |
| FNIP1 | folliculin interacting protein 1 | -0.0370196 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0358937 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0355854 |
| RAI1 | retinoic acid induced 1 | -0.0349601 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0340784 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0337755 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0334174 |
| DENND1A | DENN/MADD domain containing 1A | -0.0330158 |
| MKI67 | marker of proliferation Ki-67 | -0.0328974 |
| MCL1 | myeloid cell leukemia 1 | -0.0321403 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0318368 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0315731 |
| TNS3 | tensin 3 | -0.0314808 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0314192 |
| POM121 | POM121 transmembrane nucleoporin | -0.0313111 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0308881 |
| USP34 | ubiquitin specific peptidase 34 | -0.030841 |
| FOSL1 | FOS-like antigen 1 | -0.0308122 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0306402 |
| MYO10 | myosin X | -0.0299736 |
| ACTG1 | actin gamma 1 | -0.0299586 |
| OSMR | oncostatin M receptor | -0.0298993 |
| PODXL | podocalyxin-like | -0.0296233 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0293303 |
| PTK2 | protein tyrosine kinase 2 | -0.0290696 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0289909 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0287854 |
| ETNK1 | ethanolamine kinase 1 | -0.028235 |
| FBXO11 | F-box protein 11 | -0.0282143 |
| CCNL1 | cyclin L1 | -0.0281639 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0281297 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0275987 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0274748 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0273967 |
| TUBB6 | tubulin, beta 6 class V | -0.0273798 |
| EFNA5 | ephrin-A5 | -0.0271875 |
| CD44 | CD44 molecule (Indian blood group) | -0.0271077 |
| TMEM41B | transmembrane protein 41B | -0.026997 |
| EHBP1 | EH domain binding protein 1 | -0.0266975 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0266453 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.026465 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0264328 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0260567 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0260485 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0259014 |
| ZNF644 | zinc finger protein 644 | -0.0258847 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0258604 |
| MAP4 | microtubule-associated protein 4 | -0.0256184 |
| FLNB | filamin B, beta | -0.0256029 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0249002 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0248592 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0245609 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0243587 |
| UBXN4 | UBX domain protein 4 | -0.0243469 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0227487 |
| CALD1 | caldesmon 1 | -0.0227444 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.022361 |
| CLTC | clathrin, heavy chain (Hc) | -0.022194 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0220371 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0219693 |
| ZNF91 | zinc finger protein 91 | -0.0219556 |
| BPTF | bromodomain PHD finger transcription factor | -0.0218222 |
| JMJD1C | jumonji domain containing 1C | -0.0214688 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212806 |
| LRRC49 | leucine rich repeat containing 49 | -0.021261 |
