| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.132348 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0995408 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0891899 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0886329 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0882774 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0866443 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0779652 |
| PCBP2 | poly(rC) binding protein 2 | 0.0749726 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.066533 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0607112 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0578016 |
| CD44 | CD44 molecule (Indian blood group) | 0.0557659 |
| MYO10 | myosin X | 0.0554864 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0548393 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0548002 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0537768 |
| TGM2 | transglutaminase 2 | 0.0528401 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515489 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.049647 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0484887 |
| ASPH | aspartate beta-hydroxylase | 0.0477292 |
| ECE1 | endothelin converting enzyme 1 | 0.0474487 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0467076 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0445893 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0444402 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0442955 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0383278 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0380632 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0370543 |
| NTN4 | netrin 4 | 0.0363982 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0359759 |
| STK38L | serine/threonine kinase 38 like | 0.0356916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0356649 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0347793 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0346763 |
| RUNX1 | runt-related transcription factor 1 | 0.0342437 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0341403 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335416 |
| RPS2 | ribosomal protein S2 | 0.0329476 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0329205 |
| MSN | moesin | 0.0324315 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0319989 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0314124 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0313442 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0313152 |
| ATXN1 | ataxin 1 | 0.0310395 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0303225 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.030278 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0296741 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0296051 |
| YBX3 | Y box binding protein 3 | 0.0294173 |
| ANGPTL4 | angiopoietin-like 4 | 0.0293136 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292811 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0284784 |
| KYNU | kynureninase | 0.0280009 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.027563 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0271188 |
| SIK3 | SIK family kinase 3 | 0.0270433 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0268585 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0268579 |
| TOP1 | topoisomerase (DNA) I | 0.02667 |
| MED13L | mediator complex subunit 13-like | 0.0266529 |
| KSR1 | kinase suppressor of ras 1 | 0.0266256 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.026413 |
| APP | amyloid beta (A4) precursor protein | 0.0259572 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0258126 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0256018 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0253004 |
| PKM | pyruvate kinase, muscle | 0.0250746 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0250391 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0250368 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0249784 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0248914 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0246771 |
| MEIS1 | Meis homeobox 1 | 0.0245466 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0242464 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.024166 |
| RPL3 | ribosomal protein L3 | 0.0240261 |
| AHR | aryl hydrocarbon receptor | 0.0238477 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0238292 |
| NAV2 | neuron navigator 2 | 0.0238262 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0237293 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0236015 |
| LOXL2 | lysyl oxidase-like 2 | 0.0235506 |
| TXNRD1 | thioredoxin reductase 1 | 0.0235284 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0234413 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0233652 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0232468 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0231216 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0230985 |
| MT2A | metallothionein 2A | 0.0230607 |
| PLEC | plectin | 0.0230155 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0230043 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0227308 |
| HELZ | helicase with zinc finger | 0.0227043 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0225008 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0223866 |
| SET | SET nuclear proto-oncogene | 0.0222744 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0222578 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0222153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.183687 |
| TMSB10 | thymosin beta 10 | -0.141645 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.117388 |
| VIM | vimentin | -0.112767 |
| CDH13 | cadherin 13 | -0.108704 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.107103 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0998215 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0900861 |
| LOX | lysyl oxidase | -0.0885498 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.084505 |
| STC1 | stanniocalcin 1 | -0.0843943 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0743398 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0673011 |
| MEF2A | myocyte enhancer factor 2A | -0.0666252 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0657739 |
| OSMR | oncostatin M receptor | -0.0656551 |
| FN1 | fibronectin 1 | -0.0636974 |
| MTSS1 | metastasis suppressor 1 | -0.0634938 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0630342 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0625231 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0624932 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0618727 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0587602 |
| FAM20C | family with sequence similarity 20, member C | -0.0584287 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0549473 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0545438 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0544413 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.053673 |
| S100A6 | S100 calcium binding protein A6 | -0.0531388 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0527368 |
| RPL35A | ribosomal protein L35a | -0.0526019 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0521822 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0511121 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0509218 |
| RAI14 | retinoic acid induced 14 | -0.0494604 |
| TMEM165 | transmembrane protein 165 | -0.0492519 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0491177 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0483691 |
| HM13 | histocompatibility (minor) 13 | -0.0477659 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0473134 |
| NRG1 | neuregulin 1 | -0.0468457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0468186 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0460572 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0454538 |
| PTMA | prothymosin, alpha | -0.0450066 |
| IER3 | immediate early response 3 | -0.0449487 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0447335 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0437634 |
| GOLGA4 | golgin A4 | -0.0435174 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0421133 |
| DENND4A | DENN/MADD domain containing 4A | -0.0420008 |
| HLA-B | major histocompatibility complex, class I, B | -0.0415963 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.038927 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0384628 |
| PYGL | phosphorylase, glycogen, liver | -0.0384046 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0372588 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0362025 |
| RPLP1 | ribosomal protein, large, P1 | -0.036176 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0358962 |
| CALU | calumenin | -0.0358347 |
| TMEM263 | transmembrane protein 263 | -0.0357852 |
| IL1B | interleukin 1, beta | -0.0349385 |
| ENOSF1 | enolase superfamily member 1 | -0.0346771 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0340877 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0336613 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0333882 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0331766 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0326264 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0324695 |
| OXR1 | oxidation resistance 1 | -0.0322661 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0322002 |
| PRRX1 | paired related homeobox 1 | -0.0318838 |
| RUNX2 | runt-related transcription factor 2 | -0.0317103 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0316334 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0311769 |
| CLMP | CXADR-like membrane protein | -0.0311143 |
| DNER | delta/notch-like EGF repeat containing | -0.0310434 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.030826 |
| FTL | ferritin, light polypeptide | -0.0305635 |
| EHBP1 | EH domain binding protein 1 | -0.0301584 |
| AOPEP | aminopeptidase O (putative) | -0.0299686 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0298861 |
| SNX9 | sorting nexin 9 | -0.0294828 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.029274 |
| RPL34 | ribosomal protein L34 | -0.0291783 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0289201 |
| CUX1 | cut-like homeobox 1 | -0.0284916 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0282928 |
| NLRP1 | NLR family, pyrin domain containing 1 | -0.0281978 |
| ETV6 | ets variant 6 | -0.0281926 |
| DIAPH2 | diaphanous-related formin 2 | -0.0281458 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0280903 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0280134 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0279667 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0278901 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.027841 |
| NGLY1 | N-glycanase 1 | -0.0277917 |
| ZNF804A | zinc finger protein 804A | -0.0276103 |
| ARF4 | ADP-ribosylation factor 4 | -0.0275728 |
| CDK14 | cyclin-dependent kinase 14 | -0.0275315 |
