| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Darinaparsin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.179237 |
| LMO7 | LIM domain 7 | 0.133043 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0995353 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0890442 |
| TMSB4X | thymosin beta 4, X-linked | 0.0816378 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0785926 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0776187 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0753067 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0730521 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0724273 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0716294 |
| LAMC2 | laminin, gamma 2 | 0.0661037 |
| DSPP | dentin sialophosphoprotein | 0.0635941 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0635884 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0607881 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0595807 |
| FBXO32 | F-box protein 32 | 0.0593434 |
| HMGB2 | high mobility group box 2 | 0.0582578 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0581406 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.057556 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0569633 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0511414 |
| SQSTM1 | sequestosome 1 | 0.0509851 |
| ENO1 | enolase 1, (alpha) | 0.0485609 |
| RNF213 | ring finger protein 213 | 0.0473734 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0462927 |
| AHNAK | AHNAK nucleoprotein | 0.0458352 |
| TMSB10 | thymosin beta 10 | 0.045803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0446805 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0440947 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0433659 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0431272 |
| EFNA5 | ephrin-A5 | 0.0429557 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0421255 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421011 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0415221 |
| RRBP1 | ribosome binding protein 1 | 0.041075 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0401336 |
| LAMB3 | laminin, beta 3 | 0.0400901 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0397207 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0396903 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0395766 |
| CCND1 | cyclin D1 | 0.0395553 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0383783 |
| ASPH | aspartate beta-hydroxylase | 0.0382384 |
| KRT18 | keratin 18, type I | 0.0363582 |
| LMNA | lamin A/C | 0.0339834 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0333947 |
| KRT7 | keratin 7, type II | 0.0311361 |
| S100A6 | S100 calcium binding protein A6 | 0.0307394 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0306979 |
| RAI14 | retinoic acid induced 14 | 0.0305571 |
| PLEC | plectin | 0.0304748 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0304682 |
| SLC38A1 | solute carrier family 38, member 1 | 0.030139 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.030068 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0297863 |
| STEAP4 | STEAP family member 4 | 0.0295038 |
| TPI1 | triosephosphate isomerase 1 | 0.02903 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0285148 |
| ACTG1 | actin gamma 1 | 0.0284626 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0282766 |
| GOLGB1 | golgin B1 | 0.0281818 |
| CANX | calnexin | 0.0281649 |
| MX2 | MX dynamin-like GTPase 2 | 0.0279054 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0273944 |
| CAVIN1 | caveolae associated protein 1 | 0.0270257 |
| RPS3 | ribosomal protein S3 | 0.0270152 |
| EPCAM | epithelial cell adhesion molecule | 0.0269277 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0267735 |
| RPS8 | ribosomal protein S8 | 0.0267138 |
| SVIL | supervillin | 0.0261044 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0260358 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0259124 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0258438 |
| VCL | vinculin | 0.025686 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0256841 |
| MYOF | myoferlin | 0.0254169 |
| ARF1 | ADP-ribosylation factor 1 | 0.0249954 |
| MX1 | MX dynamin-like GTPase 1 | 0.0249135 |
| HDLBP | high density lipoprotein binding protein | 0.0248751 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0247944 |
| CD63 | CD63 molecule | 0.0246352 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0243114 |
| MYO6 | myosin VI | 0.0240846 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0238911 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0238594 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0238544 |
| CTSB | cathepsin B | 0.0238155 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0236807 |
| RIGI | RNA sensor RIG-I | 0.0236276 |
| RPS24 | ribosomal protein S24 | 0.0235748 |
| ETV6 | ets variant 6 | 0.0235575 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0235302 |
| H1-0 | H1.0 linker histone | 0.0234424 |
| RPL26 | ribosomal protein L26 | 0.0233564 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232013 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0231758 |
| SP100 | SP100 nuclear antigen | 0.0230241 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0229634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.225308 |
| POTEF | POTE ankyrin domain family, member F | -0.1874 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13804 |
| FN1 | fibronectin 1 | -0.115049 |
| HMGA1 | high mobility group AT-hook 1 | -0.113092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0801135 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0711109 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0665367 |
| CCNL1 | cyclin L1 | -0.0609266 |
| FAM3C | family with sequence similarity 3, member C | -0.0578754 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0550095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.054507 |
| MT2A | metallothionein 2A | -0.0523092 |
| PCBP2 | poly(rC) binding protein 2 | -0.0504564 |
| RNF145 | ring finger protein 145 | -0.047877 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0477967 |
| GOLGA4 | golgin A4 | -0.0455031 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0433618 |
| CDCP1 | CUB domain containing protein 1 | -0.042211 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0421851 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0418738 |
| FNDC3B | fibronectin type III domain containing 3B | -0.041821 |
| TFG | TRK-fused gene | -0.0405343 |
| FOSL1 | FOS-like antigen 1 | -0.0395988 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0392169 |
| RTN4 | reticulon 4 | -0.0384408 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0381382 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0370704 |
| UPP1 | uridine phosphorylase 1 | -0.0368089 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0359451 |
| ZNF292 | zinc finger protein 292 | -0.0349327 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0340849 |
| DTNA | dystrobrevin, alpha | -0.033418 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0321922 |
| SLMAP | sarcolemma associated protein | -0.0319745 |
| ATP11B | ATPase, class VI, type 11B | -0.0297629 |
| RPS23 | ribosomal protein S23 | -0.0293813 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0293294 |
| PTK2 | protein tyrosine kinase 2 | -0.0292172 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0291178 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.028446 |
| TXNRD1 | thioredoxin reductase 1 | -0.0280776 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0279042 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0269867 |
| CLDN4 | claudin 4 | -0.0269528 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0263247 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0263034 |
| ANXA5 | annexin A5 | -0.0262544 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0259191 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0258971 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0257633 |
| RASA2 | RAS p21 protein activator 2 | -0.0255899 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0254814 |
| USP3 | ubiquitin specific peptidase 3 | -0.0250256 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0249535 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0249505 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0243376 |
| NUP58 | nucleoporin 58 | -0.0241719 |
| CPNE8 | copine VIII | -0.0238461 |
| TAPBP | TAP binding protein (tapasin) | -0.023789 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0236779 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0236689 |
| PAPOLA | poly(A) polymerase alpha | -0.0236558 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0233047 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0232309 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232224 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.023138 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0229211 |
| MEF2A | myocyte enhancer factor 2A | -0.022492 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0224857 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0222359 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0221249 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0220967 |
| RYBP | RING1 and YY1 binding protein | -0.0218487 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0217448 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0216734 |
| RBM39 | RNA binding motif protein 39 | -0.0216029 |
| EGR1 | early growth response 1 | -0.0216026 |
| ZNF654 | zinc finger protein 654 | -0.0215035 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0214059 |
| VEGFA | vascular endothelial growth factor A | -0.0213209 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0212926 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0212674 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0212369 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0212238 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0210832 |
| NEK7 | NIMA-related kinase 7 | -0.021035 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0208833 |
| AZIN1 | antizyme inhibitor 1 | -0.0207655 |
| NCKAP1 | NCK-associated protein 1 | -0.0206185 |
| IL6ST | interleukin 6 signal transducer | -0.0205141 |
| CDC73 | cell division cycle 73 | -0.0203665 |
| FTL | ferritin, light polypeptide | -0.0202717 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0202376 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0202289 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0200683 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0200424 |
| ERBIN | erbb2 interacting protein | -0.0200248 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0199844 |
| RPS6 | ribosomal protein S6 | -0.0196989 |
